Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: Implications for virus evolution

Journal of Virology

Volumn 70, Issue 4, 1996, Pages 2490-2496

  Burrows, J M ^a   Burrows, S R ^a   Poulsen, L M ^a   Sculley, T B ^a   Moss, D J ^a   Khanna, R ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HLA A ANTIGEN; HLA ANTIGEN CLASS 1; HLA B ANTIGEN; PHYTOHEMAGGLUTININ; SYNTHETIC PEPTIDE; VIRUS ANTIGEN;

AMINO ACID SUBSTITUTION; ARTICLE; CAUCASIAN; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS; EVOLUTION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; PAPUA NEW GUINEA; PRIORITY JOURNAL;

EID: 0030009308     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.4.2490-2496.1996     Document Type: Article

References (35)

1. Aitken, C., S. K. Sengupta, C. Aedes, D. J. Moss, and T. B. Sculley, 1994. Heterogeneity within the Epstein-Barr virus nuclear antigen 2 gene in different strains of Epstein-Barr virus. J. Gen. Virol. 75:95-100.
2. Bellwood, P. S. 1989. The colonization of the Pacific, some current hypotheses, p. 1-59. In A V. S. Hill and S. W. Serjeantson (ed.), The colonization of the Pacific a genetic trail. Clarendon Press, Oxford
3. Bertoletti, A., A. Sette, F. V. Chisari, A. Penna, M. Levrero, M. De Carli, F. Fiaccadori, and C. Ferrari. 1994. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T-cells Nature (London) 369:407-410
4. Bhatia, K., C. Jenkins, M. Prasad, G. Koki, and J. Lombange. 1989. Immunogenetic studies of two recently contacted populations from Papua New Guinea. Hum. Biol. 61:45-64.
5. Burrows, S. R., J. Gardner, R. Khanna, T. Steward, D. J. Moss, S. Rodda, and A. Suhrbier. 1994. Five new cytotoxic T cell epitopes identified within Epstein-Barr virus nuclear antigen 3. J. Gen Virol. 75:2489-2493.
6. Burrows, S. R., S. J. Rodda, A. Suhrbier, H. M. Geysen, and D. J. Moss. 1992. The specificity of recognition of a cytotoxic T lymphocyte epitope. Eur. J. Immunol. 22:191-195.
7. Byrne, J. A., and M. B. Oldstone. 1984. Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo. J. Virol. 51:682-686.
8. Couilln, I., B. Culmann-Penciolelli, E. Gomard, J. Choppin, J. P. Levy, J. G. Guillet, and S. Saragosti. 1994. Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein. J. Exp. Med. 180:1129-1134.
9. Crane, G., K. Bhatia, M. Honeyman, T. Doran, N. Messel, G. Hakos, D. Tarlinton, D. B. Amos, and H. Bashir. 1985. HLA studies of Highland and Coastal New Guineans. Hum. Immunol. 12:247-260.
10. Crawford, D. H., J. A. Thomas, G. Janossy, P. Sweny, O. N. Fernando, J. F. Moorhead, and J. H. Thompson. 1980. Epstein Barr virus nuclear antigen positive lymphoma after cyclosporin A treatment in patient with renal allograft. Lancet i:1355-1356.
11. + population Science 260:98-100.
12. de Campos-Lima, P. O., V. Levitsky, J. Brooks, S. P. Lee, L. F. Hu, A. B. Rickinson, and M. G. Masucci. 1994. T-cell responses and virus evolution: loss of HLA A11 restricted CTL epitopes in Epstein-Barr virus isolates from highly All-positive populations by selective mutation of anchor residues. J Exp. Med. 179:1297-1305.
13. Gavioli, R., M. G. Kurilla, P. O. de Campos-Lima, L. E. Wallace, R. Dolcetti, R. J. Murray, A. B. Rickinson, and M. G. Masucci. 1993. Multiple HLA All-restricted cytotoxic T-lymphocyte epitopes of different immunogenicities in the Epstein-Barr virus-encoded nuclear antigen 4. J. Virol 67:1572-1578.
14. Hill, A., A. Worth, T. Elliott, S. Rowland-Jones, J. Brooks, A. Rickinson, and A. McMichael. 1995. Characterization of two Epstein-Barr virus epitopes restricted by HLA-B7. Eur. J. Immunol. 25:18-24.
15. Hill, A. V. S., D. F. O'Shaughnessy, and J. B. Clegg. 1989. Haemoglobin and globin gene variants in the Pacific, p. 246-285. In A. V. S. Hill and S. W. Serjeantson (ed.), The colonization of the Pacific: a genetic trail. Clarendon Press, Oxford.
16. Khanna, R., S. R. Burrows, M. G. Kurilla, C. A. Jacob, I. S. Misko, T. B. Sculley, E. Kieff, and D. J. Moss. 1992. Localization of Epstein-Barr virus cytotoxic T-cell epitopes using recombinant vaccinia: implications for vaccine development. J. Exp. Med. 176:169-176.
17. Khanna, R., S. R. Burrows, and D. J. Moss. 1995. Immune regulation in Epstein-Barr virus-associated diseases. Microbiol. Rev. 59:387-405.
18. Kirk, S. L. 1989. Population genetic studies in the Pacific: red cell antigen, serum protein and enzyme systems, p 60-119. In A. V. S. Hill and S. W Serjeantson (ed), The colonization of the Pacific: a genetic trail. Clarendon Press, Oxford.
19. Klenerman, P., S. Rowland-Jones, S. McAdam, J. Edwards, S. Daenke, D. Lalloo, B. Koppe, W. Rosenberg, D. Boyd, A. Edwards, et al. 1994. Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants. Nature (London) 369:403-407.
20. Lang, D. J., R. M. Garruto, and D. C. Gajdusek 1977. Early acquisition of cytomegalovirus and Epstein-Barr virus in several isolated Melanesian populations Am J. Epidemiol. 105:480
21. Lee, S. P., S. Morgan, J. Skinner, W. A. Thomas, S. R. Jones, J. Sutton, R. Khanna, H. C. Whittle, and A. B. Rickinson. 1995. Epstein-Barr virus isolates with the major HLA B35.01-restricted cytotoxic T lymphocyte epitope are prevalent in a highly B35.01-positive African population. Eur. J. Immunol. 25:102-110.
22. Moss, D. J., I. S. Misko, S. R. Burrows, K. Burman, R. McCarthy, and T. B. Sculley. 1988. Cytotoxic T-cell clones discriminate between A- and B-type Epstein-Barr virus transformants. Nature (London) 331:719-721.
23. Phillips, R. E., S. Rowland-Jones, D. F. Nixon, F. M. Gotch, J. P. Edwards, A. O. Ogunlesi, J. G. Elvin, J. A. Rothbard, C. R. Bangham, C. R. Rizza, et al. 1991. Human immunodeficiency virus genetic variation that can escape cytotoxic T-cell recognition. Nature (London) 354:453-459.
24. Pircher, H., D. Moskophidis, U. Rohrer, K. Bürki, and H. Hengartner. 1990. Viral escape by selection of cytotoxic T-cell-resistant virus variants in vivo. Nature (London) 346:629-633.
25. Rickinson, A. B., S. Finerty, and M. A. Epstein. 1977. Comparative studies on adult donor lymphocytes infected by EB virus in vivo or in vitro: origin of transformed cells arising in co-cultures with foetal lymphocytes Int. J. Cancer 19:775-782.
26. Sample, J., and E. Kieff. 1990. Transcription of the Epstein-Barr virus genome during latency in growth-transformed lymphocytes. J Virol. 64:1667-1674.
27. Sculley, T. B., A. Apolloni, R. Stumm, D. J. Moss, N. Mueller-Lantzsch, I. S. Misko, and D. A. Cooper. 1989. Expression of Epstem-Barr virus nuclear antigens 3, 4, and 6 are altered in cell lines containing B-type virus Virology 171: 401-408.
28. Serjeantson, S., K. Bryson, D. Amato, and D. Babona. 1977 Malaria and hereditary ovalocytosis. Hum. Genet. 37:161-167.
29. Serjeantson, S. W., P. G. Board, and K. K. Bhatia. 1992. Population genetics in Papua New Guinea: a perspective on human evolution, p 198-233. In R. D. Attenborough and M. P. Alpers (ed.), Human biology in Papua New Guinea: the small cosmos. Clarendon Press, Oxford.
30. Serjeantson, S. W., and A. V. S. Hill. 1989. The colonization of the Pacific: the genetic evidence, p. 286-294. In A. V S. Hill and S. W. Serjeantson (ed.), The colonization of the Pacific: a genetic trail Clarendon Press, Oxford.
31. Smith, G. L. 1994. Virus strategies for evasion of the host response to infection. Trends Microbiol. 2:81-88.
32. Thomas, J. A., M. J. Allday, and D. H. Crawford. 1991. Epstem-Barr virus-associated lymphoproliferative disorders in immunocompromised individuals. Adv. Cancer Res. 57:329-380.
33. Tsubota, H., C. I. Lord, D. I. Watkins, C. Morimoto, and N. L. Lervin. 1989. A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes. J. Exp. Med. 169:1421-1434.
34. Valerio, R. M., M. Benstead. A. M. Bray, R. A. Campbell, and N. J. Maejio. 1991 Synthesis of peptide analogs using multipin peptide synthesis method. Anal Biochem 197:168-177.
35. Wurm, S. A. 1983. Linguistic prehistory in the New Guinea area. J. Hum. Evol. 12:25-35.