C-Jun modulates apoptosis but not terminal cell differentiation in murine erythroleukemia cells

Leukemia

Volumn 16, Issue 2, 2002, Pages 233-243

  Poindessous Jazat, V ^a   Augery Bourget, Y ^a   Robert Lezenes J ^a  

^a HÔPITAL PAUL BROUSSE   (France)

Author keywords

Apoptosis; c Jun; c Jun N terminal kinase; Erythroleukemia; Terminal differentiation

Indexed keywords

DIMETHYL SULFOXIDE; PROTEIN C JUN; PROTEIN KINASE; PROTEIN P21;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CLONE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL DIVISION; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ERYTHROLEUKEMIA CELL; GENE OVEREXPRESSION; GENETIC TRANSFECTION; LEUKEMIA CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; REGULATORY MECHANISM;

EID: 0036166594     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402350     Document Type: Article

References (56)

1. Dissecting the pathways to death
2. Differentiation primary response genes and proto-oncogenes as positive and negative regulators of terminal hematopoietic cell differentiation
3. Essential role of c-myc in ara-C-induced differentiation of human erythroleukemia cells
4. The proto-oncogene c-myc and apoptosis
5. Fos and Jun: The AP-1 connection
6. Jun: Oncogene and transcription factor
7. Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun
8. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
9. AP-1 function and regulation
10. AP-1 (Fos/Jun) transcription factors in hematopoietic differentiation and apoptosis
11. The fos and jun protein families are both required for cell cycle progression in fibroblasts
12. Protooncogenes of the fos-jun family of transcription factors are positive regulators of myeloid differentiation
13. The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation
14. + myelomonocytic leukemia cells induced by ectopic expression of the protooncogene c-jun
15. Antisense c-jun overcomes a differentiation block in a murine erythroleukemia cell line
16. Amplified expression of three jun family members inhibits erythroleukemia differentiation
17. Involvement of c-Jun in the regulation of terminal differentiation genes in normal and malignant keratinocytes
18. Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation
19. Expression of c-jun during macrophage differentiation of HL-60 cells
20. Constitutive cjun expression induces partial macrophage differentiation in U-937 cells
21. Increased erythroid potentiating activity/tissue inhibitor of metalloproteinases and jun/fos transcription factor complex characterize tumor promoter-induced megakaryoblastic differentiation of K562 leukemia cells
22. Protooncogene expression in response to anticancer drugs in K562 leukemia cells: Relationship to growth inhibition and erythroid differentiation
23. Diverse functions of JNK and c-Jun in stress response and apoptosis
24. Induction of apoptosis by the transcription factor c-Jun
25. c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
26. Activation of AP-1 is required for bufalin-induced apoptosis in human leukemia U937 cells
27. C-Jun involvement in vitamin E succinate induced apoptosis of reticuloendotheliosis virus transformed avian lymphoid cells
28. JNK-1: A arotein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
29. Stress signals for apoptosis: Ceramide and c-Jun kinase
30. Kinases: Positive and negative regulators of apoptosis
31. c-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure
32. c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms
33. Activation of the c-jun protooncogene in human myeloid leukemia cells treated with etoposide
34. Transcriptional regulation of c-jun gene expression by arabinofuranosylcytosine in human myeloid leukemia cells
35. Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells
36. Role of c-jun expression increased by heat-shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis
37. Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: Stimulation of erythroid differentiation by dimethyl sulfoxide
38. Molecular and cellular mechanisms of leukemic hemopoietic cell differentiation: An analysis of the Friend system
39. Induction of transformed cells to terminal differentiation and the modulation of gene expression
40. Cross resistance to rhodamine 123 in adriamycin and daunorubicin resistant Friend leukemia cells variants
41. NF-E2p18/mafK is required in DMSO-induced differentiation of Friend erythroleukemia cells by enhancing NF-E2 activity
42. L induction during terminal differentiation of Friend erythroleukemia cells correlates with delay of apoptosis and loss of proliferative capacity but not with hemoglobinization
43. Manipulating the onset of cell cycle withdrawal in differentiated erythroid cells with cyclin-dependent kinases and inhibitors
44. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
45. C-Jun NH2-terminal kinase-mediated activation of interleukin-1β converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis
46. Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies
47. Mechanisms of resistance to apoptosis in human AML blasts: The role of differentiation-induced perturbations of cell-cycle checkpoints
48. Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53
49. Regulation of c-jun expression during hypoxic and low-glucose stress
50. Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis
51. Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin
52. Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons
53. Selective interaction of JNK proteine kinase isoforms with transcription factors
54. Transforming growth factor-β1 suppresses serum deprivation-induced death of A549 cells through differential effects on c-Jun and JNK activities
55. Functions of c-Jun in liver and hearth development
56. AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells