Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: Evidence for receptor antagonism

Arthritis and Rheumatism

Volumn 46, Issue 2, 2002, Pages 494-506

  Kalajdzic, Tanja ^a   Faour, Wissam H ^a   He, Qing Wen ^b   Fahmi, Hassan ^b   Martel Pelletier, Johanne ^b   Pelletier, Jean Pierre ^b   Di Battista, John A ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ACYL COENZYME A OXIDASE; CIGLITAZONE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DNA BINDING PROTEIN; HLA DR1 ANTIGEN; LUCIFERASE; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID;

ARTICLE; CHIMERA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOMEGALOVIRUS; DNA BINDING; DRUG EFFECT; DRUG MECHANISM; ELECTROPHORETIC MOBILITY; ENHANCER REGION; FIBROBLAST CULTURE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNOVIOCYTE; SYNOVIUM; TRANSACTIVATION; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DNA-BINDING PROTEINS; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; LIGANDS; MEMBRANE PROTEINS; OSTEOARTHRITIS; PEROXISOME PROLIFERATORS; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRIMIDINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; SULFONAMIDES; SYNOVIAL MEMBRANE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 0036166465     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10055     Document Type: Article

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