YM-50001: A novel, potent and selective dopamine D4 receptor antagonist

NeuroReport

Volumn 7, Issue 15-17, 1996, Pages 2543-2546

  Hidaka, Kazuyuki ^a   Tada, Shoko ^a   Matsumoto, Mitsuyuki ^a   Ohmori, Junya ^a   Maeno, Kyoichi ^a   Yamaguchi, Tokio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Antagonist; D2 like receptor; D4 receptor; Dopamine receptor; YM 50001

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; HALOPERIDOL; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; YM 50001;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0029851987     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-199611040-00028     Document Type: Article

References (18)

1. Sibley DR and Monsma FJ. Trends Pharmacol Sci 15, 61-69 (1992).
2. Seeman P, Neuropsychopharmacology 7, 261-284 (1992).
3. Seeman P, Guan HC, Van Tol HHM et al. Nature 365, 441-445 (1993).
4. Sokoloff P and Schwartz JC. Trends Pharmacol Sci 16, 270-275 (1995).
5. Hidaka K, Tada S, Matsumolo M et al. Br J Pharmacol 117, 1625-1632 (1996).
6. Ohmori J, Maeno K, Hidaka K et al. J Med Chem 39, 2764-2772.
7. Hidaka K, Matsumoto M, Tada S et al. Neurosci Lett 186, 145-148 (1995).
8. Mizushima S and Nagata S. Nucleic Acids Res 18, 5322 (1990).
9. Coward DM, Br J Psychiat 160, 5-11 (1992).
10. Kerwin RW, Br J Psychiat 164, 141-148 (1994).
11. Kulagowski J, Broughton H, Curtis N et al. J Med Chem 39, 1941-1942(1996).
12. Rowley M, Broughton H, Collins I et al. J Med Chem 39, 1943-1945 (1996).
13. Boyfield I, Brown T, Coldwell M et al. J Med Chem 39, 1946-1948 (1996).
14. Reynolds GP and Mason SL. J Neurochem 63, 1576-1577 (1994).
15. O'Malley KL, Harmon S, Tang L et al. New Biol 4, 137-146 (1992).
16. Van Tol HHM, Bunzow JR, Guan HC et al. Nature 350, 610-614 (1991).
17. Mrzljak L, Bergson C, Pappy M et al. Nature 381, 245-248 (1996).
18. Matsumoto M, Hidaka K, Tada S et al. J Neurochem 66, 915-919 (1996).