Pharmacological characterisation of (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(4′- methylphenyl)nortropane (PE2I) binding to the rat neuronal dopamine transporter expressed in COS cells

Neurochemistry International

Volumn 40, Issue 2, 2002, Pages 105-113

  Page, Guylène ^a,b   Chalon, Sylvie ^c   Emond, Patrick ^c   Maloteaux, Jean Marie ^a   Hermans, Emmanuel ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UPRES EA 1223   (France)

^c INSERM   (France)

Author keywords

COS cells; DA uptake; GBR 12935; Neuronal dopamine transporter; PE2I; Selective inhibitor

Indexed keywords

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLALLYL)PIPERAZINE; 1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; COMPLEMENTARY DNA; CYTOCHROME P450; DESIPRAMINE; DOPAMINE; DOPAMINE TRANSPORTER; FLUPENTIXOL; N (3 IODOPROP 2 ENYL) 2BETA CARBOMETHOXY 3BETA (4' METHYLPHENYL)NORTROPANE; NOMIFENSINE; NORTROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL STRAIN COS1; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SEQUENCE; DOPAMINE UPTAKE; DRUG BINDING; DRUG POTENCY; DRUG PROTEIN BINDING; GENETIC CODE; GENETIC TRANSFECTION; HOMOGENATE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BIOLOGICAL TRANSPORT; CERCOPITHECUS AETHIOPS; COS CELLS; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; IODINE RADIOISOTOPES; KINETICS; LIGANDS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NEURONS; NORTROPANES; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RECOMBINANT PROTEINS; TRANSFECTION; TRITIUM;

EID: 0036139253     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(01)00086-9     Document Type: Article

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