The analytical approach to the nature of lipofuscin (age pigment)

Archives of Gerontology and Geriatrics

Volumn 34, Issue 3, 2002, Pages 205-217

  Jolly, Robert D ^a   Palmer, David N ^b   Dalefield, Rosalind R ^c  

^a MASSEY UNIVERSITY   (New Zealand)

^b LINCOLN UNIVERSITY   (New Zealand)

^c CSIRO   (Australia)

Author keywords

Analytical; Ceroid lipofuscinosis; Heart; Lipofuscin; Thyroid

Indexed keywords

CEROID; LIPID; LIPOFUSCIN; METAL; MITOCHONDRIAL ENZYME; PIGMENT; PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

CATTLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONFERENCE PAPER; ENZYME SUBUNIT; GLYCATION; HEART MUSCLE; HORSE; LIPID PEROXIDATION; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; PRIORITY JOURNAL; SHEEP; SOLUBILITY; THYROID GLAND;

BOVINAE; EQUIDAE; OVIS;

EID: 0036125868     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4943(01)00219-9     Document Type: Conference Paper

References (53)

1. Isolated lipofuscin granules-a survey of a new field
2. Corpora-amylacea and the family of polyglucosan diseases
3. Peroxidation of subcellular organelles: formation of lipofuscinlike fluorescent pigments
4. When lysosomes get old
5. Lipofuscin and abnormalities in colloid in the equine thyroid gland in relation to age
6. Questioning the nature of fluorophores in age pigments
7. Lipofuscin flurophore inhibits lysosomal degradation and may cause early stages of macular degeneration
8. The lipid peroxidation theory of lipofuscinogenesis cannot be yet confirmed
9. Tissue culture loading test with storage granules from animal models of neuronal ceroid-lipofuscinosis (Batten disease): testing their lysosomal degradability by normal and Batten cells
10. The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbomide-reactive proteolipid of mitochondrial ATP synthase
11. The role of mitochondrial genome mutations in neurodegenerative disease
12. Expression studies of CLN3 protein (Battenin) in fusion with the green fluorescent protein in mammalian cells in vitro
13. Aging: a theory based on free radical and radiation chemistry
14. The properties of isolated human cardiac age pigment, 1. Preparation and physical properties
15. The properties of human cardiac age pigment, II. Chemical and enzymatic properties
16. Palmitoyl-protein thioesterase and the molecular pathogenesis of infantile neuronal ceroid-lipofuscinosis
17. Genotype-phenotype correlations in neuronal ceroid lipofuscinosis due to palmitoyl-protein thioesterase deficiency
18. Immunohistochemical localization of advanced glycation end products, pentosidine and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons
19. S 100 proteins in corpora amylacea from normai brain
20. Biosynthesis and intracellular targeting of the CLN3 protein defective in Batten disease
21. The ovine model of neuronal ceroid lipofuscinosis (NCL): its contribution to understanding the pathogenesis of Batten disease
22. Lipopigments in veterinary pathology: pathogenesis and terminology
23. Ovine ceroid-lipofuscinosis II: Pathologic changes interpreted in light of biochemical observations
24. Lipofuscin in bovine muscle and brain: a model for studying age pigment
25. The neuronal ceroid-lipofuscinoses (Batten disease)
26. Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain
27. Advanced glycation end-products and heat shock proteins accumulate in the basophilic degeneration of myocardium and the corpora amylacea of glia
28. Mitochondrial DNA mutations as an important contributor to aging and degenerative diseases
29. Turkish variant late infantile neuronul ceroid-lipofuscinosis (CLN7) may be allelic to CLN8
30. Batten's disease: eight genes and still counting
31. Formation of fluorescent pigment in Vitamin E deficiency
32. Ceroid lipofuscinosis in sheep: II. The major component of the lipopigment in liver, kidney, pancreas and brain is low molecular weight protein
33. Ceroid lipofuscinosis in sheep: bis(monoacylglycero)phosphate, dolichol, ubiquinone, phospholipids, fatty acids and fluorescence in liver lipopigment lipids
34. Ovine ceroid lipofuscinosis I: lipopigment composition is indicative of a lysosomal proteinosis
35. 2 terminal sequence
36. Mitochondrial ATP synthase subunit c storage in the ceroid-lipofuscinoses (Batten disease)
37. Storage bodies in the ceroid-lipofuscinoses (Batten disease): Low molecular weight components, unusual amino acids and reconstitution of fluorescent bodies from non-fluorescent components
38. Lipid pigments in relation to aging and dietary factors (lipofuscin)
39. The lipopigments in human brain tissue necroses, I
40. The lipopigments in human tissue necroses, II
41. Isolierung und Eigenschaffen von Lipofuscin aus Herzgewebe des Menschen
42. Association of mutations in a lysosomal protein with classical late infantile neuronal ceroid-lipofuscinosis
43. Studies on chemical nature of lipofuscin (age pigment) isolated from normal human brain
44. A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration
45. Classical late infantile neuronal ceroid lipofuscinosis fibroblasts are deficient in lysosomal tripeptidyl peptidase I
46. Mitochondrial DNA mutations in human degenerative diseases and aging
47. Studies in the neuronal ceroid-lipofuscinoses
48. Neuronal ceroid-lipofuscinosis (Batten's disease): relationship to amaurotic family idiocy