6-bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 15, 2000, Pages 1719-1721

  Isaac, Methvin ^a   Slassi, Abdelmalik ^a   Xin, Tao ^a   MacLean, Neil ^a   Wilson, Julie ^a   McCallum, Kirk ^a   Wang, Hong ^a   Demchyshyn, Lidia ^a  

^a NPS Allelix Corp   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST;

ARTICLE; DRUG BINDING; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ANALYSIS;

CELL LINE; HUMANS; INDOLES; PIPERAZINES; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; SULFONES;

EID: 0034618154     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00320-6     Document Type: Article

References (9)