Induction of micronuclei in human cell lines and primary cells by combination treatment wity γ-radiation and ethyl methanesulfonate

Mutagenesis

Volumn 17, Issue 2, 2002, Pages 177-181

  Stopper, Helga ^a   Lutz, Werner K ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CESIUM 137; MESYLIC ACID ETHYL ESTER; PROTEIN P53;

ARTICLE; CELL LINE; CELL MUTANT; CELL TYPE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; FETUS; FIBROBLAST; GAMMA RADIATION; GENOTOXICITY; HUMAN; HUMAN CELL; LINEAR SYSTEM; LUNG; LYMPHOBLASTOID CELL LINE; LYMPHOMA CELL; MICRONUCLEUS; PRIORITY JOURNAL; RADIATION DOSE; SPECIES DIFFERENCE; WILD TYPE;

ANIMALS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; ETHYL METHANESULFONATE; FEMALE; FETUS; FIBROBLASTS; GAMMA RAYS; HUMANS; LEUKEMIA L5178; LUNG; MICE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MUTAGENS; MUTATION; PREGNANCY; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036122524     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

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6. Human lymphoblastoid lines from lymph node and spleen
7. Analysis of large and small colony L5178Y tk-/- mouse lymphoma mutants by loss of heterozygosity (LOH) and by whole chromosome 11 painting: Detection of recombination
8. Evaluation of the in vitro micronucleus test as an alternative to the in vitro chromosomal aberration assay: Position of the GUM Working Group on the in vitro micronucleus test
9. Aflatoxin B1-induced mitotic recombination in L5178Y mouse lymphoma cells
10. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
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13. The mouse lymphoma L5178Y Tk+/- cell line is heterozygous for a codon 170 mutation in the p53 tumor suppressor gene
14. In vitro micronucleus assay with Chinese hamster V79 cells-results of a collaborative study with in situ exposure to 26 chemical substances
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16. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines