Substrate entropy in enzyme enantioselectivity: An experimental and molecular modeling study of a lipase

Protein Science

Volumn 11, Issue 6, 2002, Pages 1462-1471

  Ottosson, Jenny ^a   Fransson, Linda ^a   Hult, Karl ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Candida antarctica; Enantiomeric ratio; Enthalpy; Molecular dynamics; Systematic search

Indexed keywords

2 BUTANOL; ALCOHOL; FUNGAL ENZYME; HEXANOL; LIPASE B; ALCOHOL DERIVATIVE; LIPASE B, CANDIDA ANTARCTICA; TRIACYLGLYCEROL LIPASE;

ARTICLE; CALCULATION; CANDIDA ANTARCTICA; CORRELATION FUNCTION; ENANTIOMER; ENANTIOSELECTIVITY; ENTHALPY; ENTROPY; ENZYME ACTIVE SITE; ENZYME CONFORMATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; SIMULATION; TEMPERATURE DEPENDENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; ENZYME SPECIFICITY; KINETICS; METABOLISM; STEREOISOMERISM; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); CANDIDA; CANDIDA ANTARCTICA;

ALCOHOLS; BINDING SITES; COMPUTER SIMULATION; ENTROPY; KINETICS; LIPASE; MODELS, MOLECULAR; STEREOISOMERISM; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 0036102164     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.3480102     Document Type: Article

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