Computer-aided molecular modeling of the enantioselectivity of Pseudomonas cepacia lipase toward γ- and δ-lactones

Journal of Molecular Catalysis - B Enzymatic

Volumn 10, Issue 1-3, 2000, Pages 223-231

  Hwang, Bum Yeol ^a   Scheib, Holger ^b   Pleiss, Jürgen ^b   Kim, Byung Gee ^a   Schmid, Rolf D ^b  

^a Div Chem Eng Inst Molec B   (South Korea)

^b UNIVERSITY OF STUTTGART   (Germany)

Author keywords

Lactone; Lactone; Enantioselectivity; Molecular modeling; Pseudomonas cepacia lipase

Indexed keywords

BACTERIA; CATALYSIS; HYDROGEN BONDS; HYDROLYSIS; MOLECULAR STRUCTURE; STEREOCHEMISTRY;

ENANTIOSELECTIVITY; LACTONE; LIPASE;

ENZYMES;

GAMMA LACTAM DERIVATIVE; LACTONE; TETRAHYDROPYRAN DERIVATIVE; TRIACYLGLYCEROL LIPASE;

ARTICLE; BURKHOLDERIA CEPACIA; COMPUTER MODEL; DRUG SYNTHESIS; ENANTIOMER; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; IN VITRO STUDY; MOLECULAR DYNAMICS; MOLECULAR MODEL;

EID: 0034605577     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-1177(00)00129-6     Document Type: Article

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