A pool of Y2 neuropeptide Y receptors activated by modifiers of membrane sulfhydryl or cholesterol balance

European Journal of Biochemistry

Volumn 269, Issue 9, 2002, Pages 2315-2322

  Parker, Steven L ^a   Parker, Michael S ^b   Kane, Justin K ^a   Berglund, Magnus M ^c  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MEMPHIS   (United States)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Receptor masking; Receptor reserve; Receptor sequestration; Receptor signaling

Indexed keywords

2 [(TRIMETHYLAMMONIUM)ETHY]METHANETHIOSULFONATE; ALKYLATING AGENT; ARSENOSOBENZENE; CHOLESTEROL; MEMBRANE PROTEIN; N ETHYLMALEIMIDE; NEUROPEPTIDE Y2 RECEPTOR; ORGANOARSENIC DERIVATIVE; SULFONIC ACID DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FREE SYSTEM; CELL MEMBRANE; CELL MEMBRANE FLUIDITY; CELL SURFACE; CHO CELL; CONTROLLED STUDY; FOREBRAIN; GUINEA PIG; LIPID BILAYER; MEMBRANE PERMEABILITY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SURFACE PROPERTY;

ANIMALS; ARSENICALS; CELL MEMBRANE; CHO CELLS; CHOLESTEROL; CRICETINAE; ETHYLMALEIMIDE; FILIPIN; GUINEA PIGS; MESYLATES; RECEPTORS, NEUROPEPTIDE Y;

ANIMALIA; CAVIA PORCELLUS; CRICETINAE; CRICETULUS GRISEUS; SUS SCROFA;

EID: 0036098358     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2002.02903.x     Document Type: Article

References (50)

1. Endocytosis
2. Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
3. Down-regulation and desensitization of the muscarinic M1 and M2 receptors in transfected fibroblast B82 cells
4. Internalization and down-regulation of human muscarinic acetylcholine receptor m2 subtypes. Role of third intracellular m2 loop and G protein- coupled receptor kinase 2
5. Internalization of neuropeptide Y (NPY) Y1 and Y2 receptors in dispersed rat forebrain cells
6. Late endosomal/lysosomal targeting and lack of recycling of the ligand- occupied endothelin B receptor
7. Neuropeptide Y distribution in the rat brain
8. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
9. Regional distribution of Y-receptor subtype mRNAs in rat brain
10. Receptor-selective analogs demonstrate NPY/PYY receptor heterogeneity in rat brain
11. [D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide Y Y(5) receptor against with dramatic effects on food intake
12. Cloned neuropeptide Y (NPY) Y1 and pancreatic polypeptide Y4 receptors expressed in Chinese hamster ovary cells show considerable agonist-driven internalization, in contrast to the NPY Y2 receptor
13. Elevation of neuropeptide Y (NPY) in substantia innominata in Alzheimer's type dementia
14. Ligand association with the rabbit kidney and brain Y1, Y2 and Y5-like neuropeptide Y (NPY) receptors shows large subtype-related differences in sensitivity to chaotropic and alkylating agents
15. Characterization of G-protein and phospholipase C-coupled agonist binding to the Y1 neuropeptide Y receptor in rat brain. Sensitivity to G-protein activators and inhibitors and to inhibitors of phospholipase C
16. The cloned guinea pig neuropeptide Y receptor Y1 conforms to other mammalian Y1 receptors
17. Cloning and functional expression of the guinea pig neuropeptide Y Y2 receptor
18. Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells
19. Complete L-alanine scan of neuropeptide Y reveals ligands binding to Y1 and Y2 receptors with distinguished conformations
20. Blockade of pancreatic polypeptide-sensitive neuropeptide Y (NPY) receptors by agonist peptides is prevented by modulators of sodium transport. Implications for receptor signaling and regulation
21. LIGAND: A versatile computerized approach for characterization of ligand-binding proteins
22. Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue
23. Substituted-cysteine accessibility method
24. Neuropeptide Y enhances LHRH binding to rat gonadotrophs in primary culture
25. Protease-activated receptor (PAR), a novel family of G protein-coupled seven trans-membrane domain receptors: Activation mechanisms and physiological roles
26. Receptor reserve at the alpha-2 adrenergic receptor in the rat cerebral cortex
27. Receptor reserve masks partial agonist activity of drugs in a cloned rat 5-hydroxytryptamine1B receptor expression system
28. Laminin and alpha dystroglycan mediate acetylcholine receptor aggregation via a MuSK-independent pathway
29. Neuropeptide Y Y2 receptors in hypothalamic neuroendocrine areas are up-regulated by estradiol and decreased by progesterone cotreatment in the ovariectomized rat
30. Phenylarsine oxide-induced increase in alveolar macrophage surface receptors: Evidence for fusion of internal receptor pools with the cell surface
31. The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family
32. Evidence for transmembrane anchoring of extracellular matrix at acetylcholine receptor clusters
33. Lateral zone of cell-cell adhesion as the major fluid shear stress-related signal transduction site
34. Melusin is a new muscle-specific interactor for beta (1) integrin cytoplasmic domain
35. Cloning and expression of laminin alpha 2 chain (M-chain) in the mouse
36. Sulfhydryl regulation of L-selectin shedding: Phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes
37. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors
38. Uptake and binding of radiolabelled phenylarsine oxide in 3T3-L1 adipocytes
39. A role of tyrosine phosphatase in acetylcholine receptor cluster dispersal and formation
40. Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition
41. The mechanisms of reduction of protein mixed disulfides (dethiolation) in cardiac tissue
42. Evidence that tyrosine phosphorylation may increase tight junction permeability
43. Protein tyrosine phosphatase inhibitors block myeloid signal transduction through the Fc gamma RI receptor
44. Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation
45. Internalization of pancreatic polypeptide Y4 receptors: Correlation of receptor intake and affinity
46. Constitutive and interferon-gamma-induced expression of the human proteasome subunit multicatalytic endopeptidase complex-like 1
47. Cholesterol-dependent retention of GPI-anchored proteins in endosomes
48. 2+ influx into cultured dorsal root ganglion neurones of the rat via a Y2 receptor
49. Y2-type receptors for peptide YY on renal proximal tubular cells in the rabbit