Laminin and α-dystroglycan mediate acetylcholine receptor aggregation via a MuSK-independent pathway

Journal of Neuroscience

Volumn 18, Issue 4, 1998, Pages 1250-1260

  Montanaro, Federica ^a   Gee, Stephen H ^b   Jacobson, Christian ^a   Lindenbaum, Michael H ^a   Froehner, Stanley C ^b   Carbonetto, Salvatore ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Acetylcholine receptor aggregation; Agrin; Laminin; MuSK; Neuromuscular synapse; dystroglycan

Indexed keywords

ACETYLCHOLINE; AGRIN; CHOLINERGIC RECEPTOR; LAMININ; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE;

ARTICLE; CELL CULTURE; CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; MYOTUBE; NEUROMUSCULAR SYNAPSE; NEUROTRANSMISSION; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION;

EID: 0032519864     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-04-01250.1998     Document Type: Article

References (5)

1. Anderson MJ, Cohen MW (1977) Nerve-induced and spontaneous redistribution of acetylcholine receptors on cultured muscle cells. J Physiol (Lond) 268:757-773.
2. Anderson MJ, Qiao Shi Z (1996) Proteolytic disruption of laminin-integrin complexes on muscle cells during synapse formation. Mol Cell Biol 16:4972-4984.
3. Apel ED, Roberds SL, Campbell KP, Merlie JP (1995) Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex. Neuron 15:115-126.
4. Bayne EK, Anderson MJ, Fambrough DM (1984) Extracellular matrix organization in developing muscle: correlation with acetylcholine receptor aggregates. J Cell Biol 99:1486-1501.
5. Belkin AM, Zhidkova NI, Balzac F, Altruda F, Tomatis D, Maier A, Tarone G, Koteliansky VE, Burridge K (1996) β1D integrin displaces the βlA isoform in striated muscles: localization at junctional structures and signalling potential in nonmuscle cells. J Cell Biol 132:211-226.