Envelope-induced cell transformation by ovine betaretroviruses

Journal of Virology

Volumn 76, Issue 11, 2002, Pages 5387-5394

  Alberti, Alberto ^a   Murgia, Claudio ^a   Liu, Shan Lu ^a   Mura, Manuela ^a   Cousens, Chris ^a   Sharp, Mike ^a   Miller, A Dusty ^a   Palmarini, Massimo ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CELL RECEPTOR; HYALURONIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TYROSINE; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; HUMAN; IMMUNOBLOTTING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RETROVIRUS; SHEEP; SIGNAL TRANSDUCTION; VIRUS ENVELOPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BETARETROVIRUS; CELL LINE; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, VIRAL; CYTOPLASM; GENE PRODUCTS, ENV; HUMANS; JAAGSIEKTE SHEEP RETROVIRUS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, VIRUS; SHEEP; TUMOR CELLS, CULTURED;

EID: 0036097307     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.11.5387-5394.2002     Document Type: Article

References (44)

1. Avian hemangioma retrovirus induces cell proliferation via the envelope (env) gene
2. Sequence comparison of JSRV with endogenous proviruses: Envelope genotypes and a novel ORF with similarity to a G-protein-coupled receptor
3. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
4. Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase
5. Complete sequence of enzootic nasal tumor virus, a retrovirus associated with transmissible intranasal tumors of sheep
6. PCR-based detection and partial characterization of a retrovirus associated with contagious intranasal tumors of sheep and goats
7. A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity
8. Cellular survival: A play in three Akts
9. Pathology of enzootic intranasal tumour in thirty-eight goats
10. Experimental transmission of enzootic nasal intranasal tumours of goats
11. Retrovirus-associated neoplasms of the respiratory system of sheep and goats. Ovine pulmonary carcinoma and enzootic nasal tumor
12. Mechanism of cell entry and transformation by enzootic nasal tumor virus
13. Genome changes and gene expression in human solid tumors
14. Dedifferentiation of adenocarcinomas by activation of phosphatidylinositol 3-kinase
15. Simian virus 40 replication in adenovirus-transformed human cells antagonizes gene expression
16. HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity
17. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: Identification and evaluation of the resident candidate tumor suppressor genes
18. Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax
19. Direct transformation of rodent fibroblasts by Jaagsiekte sheep retrovirus DNA
20. HNF-3β is a critical factor for the expression of the Jaagsiekte sheep retrovirus (JSRV) long terminal repeat in type II pneumocytes but not in Clara cells
21. Retrovirus packaging cells based on 10A1 murine leukemia virus for production of vectors that use multiple receptors for cell entry
22. c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene
23. The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway
24. Erythroid cells rendered erythropoietin independent by infection with Friend spleen focus-forming virus show constitutive activation of phosphatidylinositol 3-kinase and Akt kinase: Involvement of insulin receptor substrate-related adapter proteins
25. The long terminal repeat of Jaagsiekte sheep retrovirus is preferentially active in differentiated epithelial cells of the lungs
26. Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer
27. Sheep pulmonary adenomatosis: A unique model of retrovirus-associated lung cancer
28. Expression of endogenous betaretroviruses in the ovine uterus: Effects of neonatal age, estrous cycle, pregnancy, and progesterone
29. Molecular cloning and functional analysis of three type D endogenous retroviruses of sheep reveal a different cell tropism from that of the highly related exogenous Jaagsiekte sheep retrovirus
30. A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells
31. Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheep
32. Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors
33. Transformation of mammalian cells by avian myelocytomatosis virus and avian erythroblastosis virus
34. Retrovirus vectors bearing Jaagsiekte sheep retrovirus Env transduce human cells by using a new receptor localized to chromosome 3p21.3
35. Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for Jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
36. Identification and validation of tumor suppressor genes
37. New transformation tricks from a barnyard retrovirus: Implications for human lung cancer
38. PIK3CA is implicated as an oncogene in ovarian cancer
39. Discovery and characterization of endometrial epithelial messenger ribonucleic acids using the ovine uterine gland knockout model
40. Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma
41. Structural organization and chromosomal localization of Hyal2, a gene encoding a lysosomal hyaluronidase
42. Regulation of surfactant protein gene transcription