Protection studies with recombinant excretory/secretory proteins of Haemonchus contortus

Parasite Immunology

Volumn 24, Issue 4, 2002, Pages 189-201

  Vervelde, L ^a   Van Leeuwen, M A W ^a   Kruidenier, M ^a   Kooyman, F N J ^a   Huntley, J F ^b   Van Die, I ^c   Cornelissen, A W C A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Carbohydrates; Haemonchus contortus; Immune response; Vaccination

Indexed keywords

CELL ENZYME; CELL EXTRACT; GLYCAN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; PROTEIN REC15; PROTEIN REC24; PROTEINASE; RECOMBINANT PROTEIN; SECRETORY PROTEIN; UNCLASSIFIED DRUG;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CELL COUNT; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; ENZYME ASSAY; EOSINOPHIL; FECES ANALYSIS; HAEMONCHUS CONTORTUS; IMMUNIZATION; INSECT CELL; LAMB; MAST CELL; MOLECULAR WEIGHT; NONHUMAN; PARASITE IDENTIFICATION; PRIORITY JOURNAL; PROVOCATION TEST; REPRODUCIBILITY; SHEEP DISEASE; SPECIES DIFFERENCE; VACCINATION; WORM INFECTION;

ANIMALS; ANTIGENS, HELMINTH; HAEMONCHUS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; RECOMBINANT PROTEINS; SHEEP; SHEEP DISEASES; VACCINATION;

ANIMALIA; HAEMONCHUS CONTORTUS; INSECTA; LAMB; OVIS ARIES;

EID: 0036091849     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.2002.00454.x     Document Type: Article

References (30)

1. The development of vaccines against gastrointestinal nematode parasites, particulary Haemonchus contortus
2. Development of vaccines against gastrointestinal nematodes
3. Vaccination against gastrointestinal nematode parasites of ruminants using gut-expressed antigens
4. Vaccination against the gastrointestinal nematodes, Haemonchus contortus, using a purified larval surface antigen
5. Protective immunity induced by vaccination with twoHaemonchus contortus excretory secretory proteins in sheep
6. Carbohydrate-dependent, MHC class II-restricted, human T cell response to bee venom allergen phospholipase A2 in allergic patients
7. Primary structures of the N-linked carbohydrate chains from honeybee venom phospholipase A2
8. Primary structure of the low-molecular-weight carbohydrate chains of Helix pomatia alpha-hemocyanin. Xylose as constituent of N-linked oligosaccharides in an animal glycoprotein
9. Haemonchus contortus glycoproteins contain N-linked oligosaccharides with novel highly fucosylated core structures
10. Specific interaction of IgE antibodies with a carbohydrate epitope of honey bee venom phospholipase A2
11. Role of complex asparagine-linked glycans in the allergenicity of plant glycoproteins
12. Core α1>3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus infected sheep
13. Protective immunity to the blood-feeding nematode Haemonchus contortus induced by vaccination with parasite low molecular weight antigens
14. Molecular characterization and expression of two putative protective excretory secretory proteins of Haemonchus contortus
15. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
16. Use of a specific immunogenic region of the Cowdria ruminantium MAP1 protein in a serological assay
17. Notes on necropsy and herbage processing techniques for gastrointestinal nematodes of ruminants
18. Immune responses of Texel sheep to excretory/secretory products of adult Haemonchus contortus
19. Quantitation of immunoglobulins in ovine sera and secretions by laser nephelometry. Comparison with the radial immunodiffusion (RID) technique
20. Production of a monoclonal antibody specific for ovine immunoglobulin E and its application to monitor serum IgE responses to Haemonchus contortus infection
21. The influence of challenge dose, duration of immunity, or steroid treatment on mucosal mast cells and on the distribution of sheep mast cell proteinase in Haemonchus contortus-infected sheep
22. The staining of eosinophil polymorphs and enterochromaffin cells in histological sections
23. The isolation and purification of a proteinase with chymotrypsin-like properties from ovine mucosal mast cells
24. Age-related protective immunity after vaccination with Haemonchus contortus excretory/secretory proteins
25. Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants on Schistosoma mansoni egg antigens
26. Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11
27. Immunisation of sheep with an integral membrane glycoprotein complex of Haemonchus contortus and with its major polypeptide components
28. A new protective antigen from Haemonchus contortus
29. Cloning and expression of cystatin, a potent cysteine protease inhibitor from the gut of Haemonchus contortus
30. Caenorhabditis elegans and the study of gene function in parasites