Age-related protective immunity after vaccination with Haemonchus contortus excretory/secretory proteins

Parasite Immunology

Volumn 23, Issue 8, 2001, Pages 419-426

  Vervelde, L ^a   Kooyman, F N J ^a   Van Leeuwen, M A W ^a   Schallig, H D F H ^a   Mackellar, A ^b   Huntley, J F ^b   Cornelissen, A W C A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b MOREDUN RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Age; Excretory secretory proteins; Haemonchus contortus; Immune response; Vaccination

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G1; PROTEIN; SECRETORY PROTEIN;

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EOSINOPHIL; HAEMONCHUS CONTORTUS; IMMUNE RESPONSE; IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; LAMB; MAST CELL; NEMATODIASIS; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROVOCATION TEST; REDUCTION; RUMINANT STOMACH; SHEEP; SHEEP DISEASE; VACCINATION;

AGE FACTORS; ANIMALS; ANTIBODIES, HELMINTH; CELL COUNT; HAEMONCHUS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; SHEEP; SHEEP DISEASES; VACCINATION;

ANIMALIA; HAEMONCHUS CONTORTUS; OVIS ARIES;

EID: 0034819750     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.2001.00391.x     Document Type: Article

References (28)

1. How long before resistance makes it impossible to control some field strains of Haemonchus contortus in South Africa with any of the modern anthelmintics?
2. The development of vaccines against gastrointestinal nematode parasites, particularly Haemonchus contortus
3. Vaccination of young Dorset lambs against haemonchosis
4. Immunization with an affinity purified protein extract from adult parasite protects lambs against infection with Haemonchus contortus
5. Further immunization biochemical studies with a protective antigen complex from microvillar membrane of the intestine of Haemonchus contortus
6. Protective immunity induced by vaccination with two Haemonchus contortus excretory secretory proteins in sheep
7. Protective immunity to the blood-feeding nematode Haemonchus contortus induced by vaccination with parasite low molecular weight antigens
8. Immunity to Haemonchus contortus infection: Relationship between age and successful vaccination with irradiated larvae
9. Age-dependent immune response in Merino sheep
10. Some relationships between age, immune responsiveness and resistance to parasites in ruminants
11. Changes in T cell subpopulations of sheep due to age and dietary protein intake; association with protective immunity to Trichostrongylus columbriformis
12. The influence of age on naturally acquired resistance to Haemonchus contortus in lambs
13. Attempts to generate immunity against Trichostrongylus colubriformis and Haemonchus contortus in young lambs by vaccination with viable parasites
14. Studies on immunity to Haemonchus contortus infection: The elimination of a challenge infection by immune sheep
15. Haemonchus contortus: Attempts to immunise lambs with irradiated larvae
16. Notes on necropsy and herbage processing techniques for gastrointestinal nematodes of ruminants
17. Immune responses of Texel sheep to excretory/secretory products of adult Haemonchus contortus
18. Quantitation of immunoglobulins in ovine sera and secretions by laser nephelometry. Comparison with the radial immunodiffusion (RID) technique
19. Production of a monoclonal antibody specific for ovine immunoglobulin E and its application to monitor serum IgE responses to Haemonchus contortus infection
20. The influence of challenge dose, duration of immunity, or steroid treatment on mucosal mast cells and on the distribution of sheep mast cell proteinase in Haemonchus contortus-infected sheep
21. The staining of eosinophil polymorphs and enterochromaffin cells in histological sections
22. Vaccination of merino lambs against haemonchosis with membrane-associated proteins from adult parasite
23. The potential value of integral membrane proteins in the vaccination of lambs against Haemonchus contortus
24. Immune exclusion, a mechanism of protection against the ovine nematode Haemonchus contortus
25. Failure to vaccinate against Haemonchus contortus with functional metabolic antigens identified by immunoelectrophoresis
26. Protection of lambs with a purified metabolite of exsheated third-stage Haemonchus contortus larvae
27. The abomasal histology of worm-free sheep give primary and challenge infections of Haemonchus contortus
28. Prospects for vaccines of helminth parasites of grazing ruminants