Beneficial effect of T-1095, a selective inhibitor of renal Na+-glucose cotransporters, on metabolic index and insulin secretion in spontaneously diabetic GK rats

Clinical and Experimental Pharmacology and Physiology

Volumn 29, Issue 5-6, 2002, Pages 386-390

  Nunoi, Kumiko ^a   Yasuda, Koichiro ^a   Adachi, Tetsuya ^a   Okamoto, Yoshimasa ^a   Shihara, Nobuyuki ^a   Uno, Mika ^a   Tamon, Akiko ^a   Suzuki, Naoko ^a   Oku, Akira ^b   Tsuda, Kinsuke ^a  

^a KYOTO UNIVERSITY   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Insulin secretion; Perfused pancreas; Phlorizin; Type 2 diabetes

Indexed keywords

3 (5 BENZOFURANYL) 1 [2 HYDROXY 6 [6 O (METHOXYCARBONYL) BETA DEXTRO GLUCOPYRANOSYL] 4 METHYLPHENYL] 1 PROPANONE; ANTIDIABETIC AGENT; GLUCOSE; GLUCOSE TRANSPORTER; GLYCOSYLATED HEMOGLOBIN; INSULIN; PROTEIN INHIBITOR; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG SELECTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HEMOGLOBIN DETERMINATION; INSULIN RELEASE; ISOLATED ORGAN; KIDNEY TUBULE ABSORPTION; MALE; METABOLIC PARAMETERS; NONHUMAN; PANCREAS; RAT; SODIUM TRANSPORT;

EID: 0036090806     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2002.03671.x     Document Type: Article

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