Antihyperglycemic effect of T-1095 via inhibition of renal NA+-glucose cotransporters in streptozotocin-induced diabetic rats

Biological and Pharmaceutical Bulletin

Volumn 23, Issue 12, 2000, Pages 1434-1437

  Oku, Akira ^a   Ueta, Kiichiro ^a   Arakawa, Kenji ^a   Kano Ishihara, Tomomi ^a   Matsumoto, Mamoru ^a   Adachi, Tetsuya ^b   Yasuda, Koichiro ^b   Tsuda, Kinsuke ^b   Saito, Akira ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Diabetes mellitus; Na+ glucose cotransporter; Phlorizin; Streptozotocin; T 1095

Indexed keywords

3 (5 BENZOFURANYL) 1 [2 HYDROXY 6 [6 O (METHOXYCARBONYL) BETA DEXTRO GLUCOPYRANOSYL] 4 METHYLPHENYL] 1 PROPANONE; 3 (BENZO[B]FURAN 5 YL) 2',6' DIHYDROXY 4' METHYLPROPIOPHENONE 2' O (6 O METHOXYCARBONYL) BETA DEXTRO GLUCOPYRANOSIDE; 3 (BENZO[B]FURAN 5 YL) 2',6' DIHYDROXY 4' METHYLPROPIOPHENONE 2' O BETA DEXTRO GLUCOPYRANOSIDE; ACARBOSE; DRUG METABOLITE; GLUCOPYRANOSIDE; GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; ORAL ANTIDIABETIC AGENT; PHLORIZIN; SODIUM; STREPTOZOCIN; T 1095A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG DEPENDENCE; DRUG EFFECT; DRUG POTENCY; GLUCOSE ABSORPTION; GLUCOSE BLOOD LEVEL; GLUCOSURIA; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN RELEASE; KIDNEY TUBULE EPITHELIUM; MALE; NEPHRECTOMY; NONHUMAN; RAT; STREPTOZOCIN DIABETES;

EID: 0034533892     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.23.1434     Document Type: Article

References (24)