Antidiabetic effect of T-1095, an inhibitor of Na+-glucose cotransporter, in neonatally streptozotocin-treated rats

European Journal of Pharmacology

Volumn 391, Issue 1-2, 2000, Pages 183-192

  Oku, Akira ^a   Ueta, Kiichiro ^a   Nawano, Masao ^a   Arakawa, Kenji ^a   Kano Ishihara, Tomomi ^a   Matsumoto, Mamoru ^b   Saito, Akira ^a   Tsujihara, Kenji ^a   Anai, Motonobu ^c   Asano, Tomoichiro ^c  

^a Discovery Research Laboratories   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Glucose clamp; Glucose tolerance test; Glucose transporter; Insulin secretion; Insulin sensitivity; Na+ glucose cotransporter; Phlorizin; Streptozotocin; T 1095

Indexed keywords

3 (5 BENZOFURANYL) 1 [2 HYDROXY 6 [6 O (METHOXYCARBONYL) BETA DEXTRO GLUCOPYRANOSYL] 4 METHYLPHENYL] 1 PROPANONE; ANTIDIABETIC AGENT; GLUCOSE TRANSPORTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; GLUCOSE URINE LEVEL; GLUCOSURIA; HYPERGLYCEMIA; INSULIN RELEASE; INSULIN SENSITIVITY; MALE; NONHUMAN; POLYURIA; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ANIMALS; ANIMALS, NEWBORN; BLOOD GLUCOSE; CARBONATES; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE TRANSPORTER TYPE 4; GLUCOSIDES; GLYCOSURIA; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MICROVILLI; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; RATS; RATS, SPRAGUE-DAWLEY; SODIUM;

EID: 0034629266     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00016-9     Document Type: Article

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