Peak of circadian melatonin rhythm occurs later within the sleep of older subjects

American Journal of Physiology - Endocrinology and Metabolism

Volumn 282, Issue 2 45-2, 2002, Pages

  Duffy, Jeanne F ^a   Zeitzer, Jamie M ^a   Rimmer, David W ^a   Klerman, Elizabeth B ^a   Dijk, Derk Jan ^a   Czeisler, Charles A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Aging; Biological rhythms; Chronobiology; Constant routine

Indexed keywords

MELATONIN;

AGED; AGING; ARTICLE; BLOOD SAMPLING; BODY TEMPERATURE; CHRONOBIOLOGY; CIRCADIAN RHYTHM; CONTROLLED STUDY; FEMALE; HORMONE RELEASE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SLEEP; SLEEP WAKING CYCLE;

EID: 0036084963     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00268.2001     Document Type: Article

References (52)

1. Sleep in normal aging and dementia
2. Photic regulation of melatonin in humans: Ocular and neural signal transduction
3. Circadian and sleep-dependent regulation of hormone release in humans
4. Bright light induction of strong (type 0) resetting of the human circadian pacemaker
5. Human sleep: Its duration and organization depend on its circadian phase
6. Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans
7. Circadian regulation of human sleep and age-related changes in its timing, consolidation and EEG characteristics
8. Ageing and the circadian and homeostatic regulation of human sleep during forced desynchrony of rest, melatonin and temperature rhythms
9. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance
10. Constant routine
11. Later endogenous circadian temperature nadir relative to an earlier waketime in older people
12. Sleep complaints among elderly persons: An epidemiologic study of three communities
13. Improvement of sleep quality in elderly people by controlled-release melatonin
14. The relationship between urinary 6-sulphatoxymelatonin rhythm and insomnia in old age
15. Melatonin replacement therapy of elderly insomniacs
16. The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: Assessment in a clinical trial of melatonin replacement
17. Age-dependent reduction in serum melatonin concentrations in healthy human subjects
18. The suprachiasmatic nucleus and rhythmic pineal melatonin production
19. Pineal N-acetyltransferase and hydroxyindole-O-methyltransferase: Control by the retinohypothalamic tract and the suprachiasmatic nucleus
20. Later circadian phase of plasma melatonin relative to usual waketime in older subjects
21. The endogenous melatonin profile as a marker for circadian phase position
22. The dim light melatonin onset as a marker for circadian phase position
23. Circadian rhythms of activity in healthy young and elderly humans
24. Changes in endocrine circadian rhythms as markers of physiological and pathological brain aging
25. Sleep patterns and problems in elderly general practice attenders: An Australian survey
26. The subjective assessment of normal sleep patterns
27. Sleep and aging
28. Adaptation to abrupt time shifts of the oscillator[s] controlling human circadian rhythms
29. Rhythmic vs. homeostatic influences on mood, activation, and performance in young and old men
30. Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat
31. Visual pathways and the central neural control of a circadian rhythm in pineal serotonin N-acetyltransferase activity
32. A retinohypothalamic projection in the rat
33. Changes in circadian rhythms and sleep quality with aging: Mechanisms and interventions
34. Geriatrics: Sleep disorders and aging
35. Circadian variation of sleep tendency in elderly and young adult subjects
36. Circadian rhythms of melatonin and cortisol in aging
37. Age-related changes in the circadian rhythm of plasma cortisol in man
38. Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions
39. Diurnal and ultradian rhythms in human endocrine function: A minireview
40. Effects of gender and age on the levels and circadian rhythmicity of plasma cortisol
41. Alterations of circadian rhythmicity and sleep in aging: Endocrine consequences
42. Endocrine and other biological rhythms
43. Circadian temperature rhythms in young adult and aged men
44. Alterations in nocturnal serum melatonin levels in humans with growth and aging
45. Melatonin and circadian rhythmicity in vertebrates: Physiological roles and pharmacological effects
46. Chronobiology of aging: Temperature, sleep-wake rhythms and entrainment
47. Improvement of sleep quality by melatonin
48. Do plasma melatonin concentrations decline with age?
49. Endogenous melatonin levels and the fate of exogenous melatonin: Age effects
50. Sleep-inducing effects of low doses of melatonin ingested in the evening
51. The dependence of onset and duration of sleep on the circadian rhythm of rectal temperature