Ageing and the circadian and homeostatic regulation of human sleep during forced desynchrony of rest, melatonin and temperature rhythms

Journal of Physiology

Volumn 516, Issue 2, 1999, Pages 611-627

  Dijk, Derk Jan ^a   Duffy, Jeanne F ^a   Kiel, Eymard ^a   Shanahan, Theresa L ^a   Czeisler, Charles A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MELATONIN;

ADULT; AGED; AGING; ARTICLE; BLOOD LEVEL; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORE TEMPERATURE; FEMALE; HOMEOSTASIS; HUMAN; HUMAN EXPERIMENT; LATENT PERIOD; MALE; NORMAL HUMAN; POLYSOMNOGRAPHY; PRIORITY JOURNAL; REM SLEEP; REST; SLEEP; TEMPERATURE; AGE DISTRIBUTION; HORMONE BLOOD LEVEL; SLEEP STAGE; SLEEP TIME; WAKEFULNESS;

NON-PROGRAMMATIC;

ADULT; AGED; AGING; BODY TEMPERATURE; CIRCADIAN RHYTHM; ELECTROCARDIOGRAPHY; FEMALE; HOMEOSTASIS; HUMANS; MALE; MELATONIN; MIDDLE AGED; REST; SLEEP; SLEEP, REM; WAKEFULNESS;

EID: 0033560847     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.0611v.x     Document Type: Article

References (56)

1. AKERSTEDT, T. & GILLBERG, M. (1981). The circadian variation of experimentally displaced sleep. Sleep 4, 159-169.
2. AKERSTEDT, T. & GII.LHERO, M. (198G). Sleej) duration and the power spectral density of the KEG. Electroencephalograpliy 'anil Clinical Neurophysiology 64, 119-122.
3. BLIWI.SE, D. L. (1993). Sleep in normal aging and dementia. Sleep 16, 40-81.
4. BROWN, E. X., CHOE, Y., SHANAHAN, T. L. & CZEISLER, C. A. (1997). A mathematical model of diurnal variations in human plasma melatonin levels. American Journal of Physiology 272, E50G-51C.
5. BROWN, E. X. & CZEISLER, C. A. (1992). The statistical analysis of circadian phase and amplitude in constant-routine core-temperature data. Journal of Biological Ehyihnis 7, 177-202.
6. CAMPBELL, S. S., D.uvsox, D. & ANDERSOX, M. \Y. (1993). Alleviation of sleep maintenance insomnia with timed exposure to bright light. Journal of the A merican Geriatrics Society 41, 829-836.
7. CAMPBELL, S. S. & MURPHY, P. J. (1998). Relationships between sleep and body temperature in middle-aged and older subjects. Journal of - the American Geriatrics Society 46, 458-462.
8. CARRIER, J., MONK, T. H., BUYSSE, D. J. & KurFER, D. J. (1990). Inducing a G-hour phase advance in the elderly: effects on sleep and temperature rhythms. Journal of Sleep Research 5, 99-105.
9. CARSKADON, M. A. & DEMENT, W. C. (1981). Cumulative effects of sleep restriction on daytime sleepiness. Psychophysiology 18, 107-113.
10. CZEISLER, C. A., DUFFY, J. F., SlIAXAHAX, T. L., BROWN, E. X, JIlTCHELL, J. R, DlJK, D.-J., RlMMER, D. W., RoXDA, J. M., ALLAN", J. S., EMEXS, J. S. & KROXAUER, R. E. (1995). Reassessment of the intrinsic period (T) of the human circadian pacemaker in young and older subjects. Sleep Research 24A, 505.
11. CZEISLER, C. A., DUMOXT, II., DUFFY, J. F., STEIXBERG, J. D., RICHARDSON, G. S., BROWN, E. N., SâXCHEZ, R., Rîos, C. D. & ROXDA, J. M. (1992). Association of sleep-wake habits in older people with changes in output of circadian pacemaker. Lancet 340, 933-936.
12. CZEISLER, C. A., WEITZMAX, E. D., MOORE-EDE, M. C., ZIMJIERMAX, J. C. & KXAUER, R. S. (1980). Human sleep: Its duration and organization depend on its circadian phase. Science 210, 1264-1267.
13. DAAX, S., BEERSMA, D. G. M. & BORBéLY, A. A. (1984). Timing of human sleep: Recovery process gated by a circadian pacemaker. American Journal of Physiology 246, R161-178.
14. DIJK, D.-J., BEERSMA, D. G. M. & DAAN, S. (1987). EEG power density during nap sleep: reflection of an hourglass measuring the duration of prior wakefulness. Journal of Biological Rhythms 2, 207-219.
15. DIJK, D.-J. & CZEISLER, C. A. (1994). Paradoxical timing of the circadian rhythm of sleep propensity serves to consolidate sleep and wakefulness in humans. Xeuroscience Letters 166, 63-68.
16. DIJK, D.-J. & CZEISLER, C. A. (1995). Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroehcephalographic slow waves and sleep spindle activity in humans. Journal of Neuroscience 15, 3526-3538.
17. DIJK, D.-J., DUFFY, J. F. & CZEISLER, C. A. (1992). Circadian and sleep/wake dependent aspects of subjective alertness and cognitive performance. Journal of Sleep Research I, 112-117.
18. DIJK, D.-J., SHAXAHAX, T. L., DUFFY, J. F., RONDA, J. M. & CZEISLER, C. A. (1997). Variation of electroencephalographic activity during non-rapid eye movement and rapid eye movement sleep with phase circadian melatonin rhythm in humans. Journal of Physiology 505, 851-858.
19. DUFFY, J. F., DIJK, D.-J., KLERMAN, E. B. & CZEISLER, C. A. (1998). Later endogenous circadian temperature nadir relative to an earlier wake time in older people. American Journal of Physiology 275, R1478-1487.
20. EDGAR, D. M., DEMENT, \V. C. & FULLER, C. A. (1993). Effect of SCX lesions on sleep in squirrel monkej-s: Evidence for opponent processes in sleep-wake regulation. Journal of Neuroscience 13, 1065-1079.
21. EIILF.RS, C. L. & KUPFER, D. J. (1989). Effects of age on delta and REM sleep parameters. Ehclroencephalography and Clinical Xeurophysiology 72, 118-125.
22. FKINBEKO, I. (1974). Changes in sleep cycle patterns with age. Journal of Psychiatric Research 10, 283-306.
23. GARFIXKEL, D., LAUDOX, M., XOF, D. & ZISAPEL, X. (1995). Improvement of sleep quality in elderly people by controlled-release melatonin. Lancet 346, 541-544.
24. HAIMOV, I., LAUDON, M., ZISAPEL, X, SOUROUJON-, M., XOF, D., SIILITXER, A., HERER, P., TZISCIIIXSKY, 0. & LAVIE, P. (1994). Sleep disorders and melatonin rhythms in elderly people. British Mfdical Journal 309, 167.
25. HAI.MOV, I. & LAVIE, P. (1997). Orcadian characteristics of sleep propensity function in healthy elderly: A comparison with young adults. Sleep 20, 294-300.
26. HIRSIIKOWITZ, M., MOORE, C. A., HAMILTON, C. H. Ill, RANDO, K. C. & KARACAN, I. (1992). Polysomnography of adults and elderly: Sleep architecture, respiration, and leg movement. Journal of Clinical Xeurophysiology 9, 50-62.
27. HUGHES, R. J. & BADIA, P. (1997). Sleep-promoting and hypothermie effects of daytime melatonin administration in humans. Sleep 20, 124-131.
28. HUME, K. & MILLS, J. (1977). Rhythms of REM and slow-wave sleep in subjects living on abnormal time schedules. Waking and Sleeping I, 291-290.
29. KLEIN, D. C., MOORE, R. Y. & REPPERT, S. M. (1991). Suprachiasmaiic Nucleus: The Mind's Clock. Oxford University Press, New York.
30. LAVIE, P. (1997). Melatonin: Role in gating nocturnal rise in sleep propensity. Journal of Biological Rhythms 12, 657-665.
31. Liu, G, WEAVER, D. R., JIN, X., SHEARMAN, L. P., PIESCHL, R. L., GRIBKOFF, V. K. & REPPERT, S. M. (1997). Molecular dissection of two distinct actions of melatonin on the supraehiasmatic circadian clock. Neuron 19,91-102.
32. MILES, L. E. & DEMENT, W. C. (1980). Sleep and aging. Sleep 3, 119-220.
33. MOHNE, M. L., POI.LAK, G P., MONK, T. H., LESTEU, L. S., WAGNER, D. R., ZENDELL, S. M., GRAEBER, R. G, SALTER, G A. & HIRSCH, E. (1992). Age-related differences in recovery from simulated jet lag. Sleep 15, 28-40.
34. MONK, T. H., BUYSSE, D. J., REYNOLDS, G F. Ill, JARRETT, D. B. & KUPFER, D. J. (1992). Rhythmic vs. homeostatic influences on mood, activation, and performance in young and old men. Journal of Gerontology 47, P221-227.
35. MONK, T. H., BUYSSE, D. J., REYNOLDS, G F. Ill, KUPFER, D. J. & HOUCK, P. R. (1995). Circadian temperature rhythms of older people. Experimental Gerontology 30, 455-474.
36. MONK, T. H. & MOLINE, M. L. (1988). Removal of temporal constraints in the middle-aged and elderly: effects on sleep and sleepiness. Sleep 11, 513-520.
37. MYERS, B. L. & RADIA, P. (1995). Changes in circadian rhythms and sleep quality with aging: Mechanisms and interventions. Neuro.icience and Biobehai-ioral Revieu-s 19, 553-571.
38. PRINZ, P. X., VITIELLO, M. V., RASKIND, M. A. & THORPY, M. J. (1990). Geriatrics: Sleep disorders and aging. New England Journal of Medicine 323, 520-520.
39. RECHTSCHAFFEN, A. & KALES, A. (1968). A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. US Government Printing Office, Washington, DC.
40. REDIEIIS, M. H., REIS, J. S. & CRF.ASON, X. S. (1990). Sleep in old age: Focus on gender differences. Sleep 13, 410-424.
41. REYNOLDS, C. F. Ill, JKNNINGS, J. R., HOCH, C. G, MONK, T. H., BER.MAN, S. R., HALL, F. T., MATZZIE, J. V., BUYSSE, D. J. & KUPFER, D. J. (1991). Daytime sleepiness in healthy 'old old': A comparison with young adults. American Geriatric Association 39, 957-902.
42. REYNOLDS, C. F. Ill, KUPFER, D. J., HOCH, C. G, HOUCK, P. R., STACK, J. A., BER.MAN, S. R., CAMPIIKI.I., P. I. & ZIMMER, B. (1987). Sleep deprivation as a probe in the elderly. Archives of Gentml Psychiatry 44, 982-990.
43. SACK, R. L., H to HEM, R. J., EIX:AR, D. M. & LEWY, A. J. (1997). Sleep-promoting effects of melatonin: At what dose, in whom, under what conditions, and by what mechanisms? Sleep 20, 908-915.
44. SIIAXAHAX, T. L. & CzEisLF.H, C. A. (1991). Light exposure induces equivalent phase shifts of the endogenous circadian rhythms of circulating plasma melatonin and core body temperature in men. Journal of Clinical Endocrinology and Metabolism 73, 227-235.
45. SlIERIX, J. E., SlIIROMANI, P. J-, McCAKLEY, R. W. & SAPER, C. B. (1996). Activation of ventrolateral preoptic neurons during sleep. Science 271, 210-219.
46. SIIOCHAT, T., LUBOSHITZKY, R. & LAVIE, P. (1997). Nocturnal melatonin onset is phase locked to the primary sleep gate. American Journal of Physiology 273, R304-370.
47. STERIADE, 51., McCoRMicK, D. A. & SEJNOWSKI, T. J. (1993). Thalamocortical oscillations in the sleeping and aroused brain. Science 262, G79-G85.
48. VAN COEVORDEX, A., MOCKEL, J., LAUREST, E., KERKHOFS, M., L'HERMITE-HALéRIAUX, M., DECOSTER, G., NéVé, P. & VAX CAUTER, E. (1991). Neuroendocrine rhythms and sleep in aging men. American Journal of Physiology 260, E651-661.
49. VAN SOMEREX, E. J. W., MlRMIRAX, il. & SWAAB, D. F. (1993). Nonpharmacological treatment of sleep and wake disturbances in aging and Alzheimer's disease: Chronobiological perspectives. Behavioural Brain Research 57, 235-253.
50. WEBB, W. B. (1981). Sleep stage responses of older and younger subjects after sleep deprivation. Electroencephalography and Clinical iVeurophysiology 52, 3C8-371.
51. WEBB, \V. B. & AGXEW, H. V. (1971). Stage 4 sleep: Influence of time course variables. Science 174, 1354-1356.
52. WEI, H. G., RIEL, E., CZEISLER, G A. & DIJK, D.-J. (1999). Attenuated amplitude of circadian and sleep-dependent modulation of sleep spindle characteristics in elderly human subjects. Neurostience Letters 260, 29-32.
53. WEITZMAN, E. D., MOLIXE, M. L., CZEISLER, C. A. & ZIMMERMAN, J. C. (1982). Chronobiology of aging: Temperature, sleep-wake rhythms and entrainment. Xeurobiohgy of Aging 3, 299-309.
54. WEITZMAN, E. D., XOOF.IRE, C., PERLOW, M., FUKUSHIMA, D., SASSIX, J., JIcGREOOR, P., GALLAGHER, T. F. & HELLMAN, L. (1974). Effects of a prolonged 3-hour sleep-wake cycle on sleep stages, plasma cortisol, growth hormone, and body temperature in man. Journal of Clinical Endocrinology and Metabolism 38, 1018-1030.
55. ZULLEY, J. (1980). Distribution of REM sleep in entrained 24 h and free-running sleep-wake cycles. Sleep 2, 377-389.
56. ZULLEY, J., WEVER, R. & ASCHOFF, J. (1981). The dependence of onset and duration of sleep on the circadian rhythm of rectal temperature. Pflügers Archiv 391, 314-318.