The thumb domain of the p51-subunit is essential for activation of HIV reverse transcriptase

Biochemistry

Volumn 38, Issue 46, 1999, Pages 15097-15103

  Morris, May C ^a   Berducou, Cedric ^a   Mery, Jean ^a   Heitz, Frederic ^a   Divita, Gilles ^a  

^a Centre National de la Recherche Scientifique   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE; RNA DIRECTED DNA POLYMERASE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME CONFORMATION; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; DIMERIZATION; DNA, SINGLE-STRANDED; ENZYME ACTIVATION; ENZYME STABILITY; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RNA, TRANSFER, TYR; RNA-DIRECTED DNA POLYMERASE; TEMPLATES, GENETIC;

HUMAN IMMUNODEFICIENCY VIRUS; RNA VIRUSES;

EID: 0033576276     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9914558     Document Type: Article

References (37)

1. Baltimore, D. (1970) Nature 226, 1209-1211.
2. Temin, H. M., and Mizutani, S. (1970) Nature 226, 1211-1213.
3. De Clercq, E. (1992) AIDS Res. Hum. Retro. 8, 119-134.
4. Mitsuya, H., Yarchoan, R., and Broder, S. (1990) Science 249, 1533-1544.
5. Merluzzi, V. J., Hargrave, K. D., Labadia, M., Grozinger, K., Skoog, M., Wu, J. C., Shin, C. K., Eckner, K., Hattox, S., Adams, J., Rosehthal, A. S., Faanes, R., Eckner, R. J., Koup, R. A., and Sullivan, J. L. (1990) Science 250, 1411-1413.
6. Di Marzo Veronese, F., Copeland, T. D., De Vico, A. L., Rahman, R., Oroszlan, S., Gallo, M., and Sarngadharan, M. G. (1986) Science 231, 1289-1291.
7. Lightfoote, M. M., Colligan, J. E., Folks, T. M., Fauci, A. S., Martin, M. A., and Venkatesan, S. (1986) J. Virol. 60, 771-775.
8. Kohlstaedt, L. A., Wang, J., Friedman, J. M., Rice, P. A., and Steitz, T. A. (1992) Science 256, 1783-1790.
9. Jacobo-Molina, A., Ding, J., Nanni, R. G., Clark, A. D., Jr., Lu, X., Tantillo, C., Williams, R. L., Kamer, G., Ferris, A. L., Clark, P., Hizi, A., Hughes, S. H., and Arnold, E. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 6320-6324.
10. Esnouf, R., Ren, J., Ross, C., Jones, Y., Stammers, D., and Stuart, D., (1995) Nat. Struct. Biol. 2, 303-308.
11. Ren, J., Esnouf, R., Garman, E., Somers, D., Ross, C., Kirby, I., Keeling, J., Darby, G., Jones, Y., Stuart, D., and Stammers, D. (1995) Natl. Struct. Biol. 2, 293-302.
12. Rodgers, D. W., Gamblin, S. J., Harris, B. A., Ray, S., Culp, J. S., Hellmig, B., Woolf, D. J., Debouck, C., and Harrison, S. C. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 1222-1226.
13. Huang, H., Chopra, R., Verdine, G. L., and Harrison, S. C. (1998) Science 282, 1669-1675.
14. Divita, G., Rittinger, K., Geourjon, C., Deleage, G., and Goody, R. S. (1995) J. Mol. Biol. 245, 508-521.
15. Wang, J., Smerdon, S. J., Jäger, J., Kohlstaedt, L. A., Rice, P. A., Friedman, J. M., and Steitz, T. A. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 7242-7246.
16. Becerra, S. P., Kumar, A., Lewis, M. S., Widen, S. G., Abbotts, J., Karawya, E. M., Hughes, S. H., Shiloach, J., and Wilson, S. H. (1991) Biochemistry 30, 11707-11719.
17. Baillon, J. G., Nashed, N. T., Kumar, A., Wilson, S. H., and Jerina, D. M. (1991) New Biol. 3, 1015-1019.
18. Debyser, Z., and De Clercq, E. (1996) Protein Sci. 5, 278-298.
19. Divita, G, Restle, T., Goody, R. S., Chermann, J. C., and Baillon, J. G. (1994) J. Biol. Chem. 269, 13080-13083.
20. Divita, G., Baillon, J. G., Rittinger, K., Chermann, J. C., and Goody, R. S. (1995) J. Biol. Chem. 270, 28642-28646.
21. Mishima, Y., and Steitz, J. A. (1995) EMBO J. 14, 2679-2687.
22. Arts, E. J., Miller, J. T., Ehresmann, B., and Le Grice, S. J. (1998) J. Biol. Chem. 273, 14523-14532.
23. Dufour, E., Reinbolt, J., Castroviejo, M., Ehresmann, B., Litvak, S., Tarrago-Litvak, L., and Andreola, M.-L. (1999) J. Mol. Biol. 285, 1339-1346.
24. Isel, C., Westhof, E., Massire, C, Le Grice, S. F. J., Ehresmann, B., Ehresmann, C., and Marquet, R. (1999) EMBO J. 18, 1038-1048.
25. Restle, T., Muller, B., and Goody, R. S. (1990) J. Biol. Chem. 265, 8986-8988.
26. Muller, B., Restle, T., Weiss, S., Gautel, M., Sczakiel, G., and Goody, R. S. (1989) J. Biol. Chem. 264, 13975-13978.
27. Restle, T., Müller, B., and Goody, R. S. (1992) FEBS Lett. 300, 97-100.
28. Müller, B., Restle, T., Kühnel, H., and Goody, R. S. (1991) J. Biol. Chem. 266, 14709-14713.
29. Bradford, M. (1976) Anal. Biochem. 72, 248-254.
30. Mery, J., Granier, C., Juin, M., and Brugidou, J. (1993) Int. J. Pept. Protein Res. 42, 44-52.
31. Wain-Hobson, S., Sonigi, P., Danos, O., Cole, S., and Alison, M. (1985) Cell 40, 9-17.
32. Müller, B., Restle, T., Reinstein, J., and Goody, R. S. (1991) Biochemistry 30.
33. Thrall, S. H., Reinstein, J., Wöhrl, B. M., and Goody, R. S. (1996) Biochemistry, 35, 4609-4618.
34. Divita, G., Rittinger, K., Restle, T., Immendorfer, U., and Goody, R. S. (1995) Biochemistry 34, 16337-16346.
35. Goel, R., Beard, W. A., Kumar, A., Casas-Finet, J. R., Strub, M. P., Stahl, S. J., Lewis, M. S., Bebenek, K., Becerra, P., Kunkel, T. A., and Wilson, S. H. (1993) Biochemistry 32, 13012-13018.
36. Jacques, P. S., Wöhrl, B. M., Howard, K. J., and Le Grice, S. (1994) J. Biol. Chem. 269, 1388-1393.
37. Wöhrl, B. M., Krebs, R., Thrall, S. H., Le Grice, S. J. F., Scheidig, A., and Goody, R. S. (1997) J. Biol. Chem. 272, 17581-17587.