FK506 in the maturation of dendritic cells

Haematologica

Volumn 87, Issue 7, 2002, Pages 679-687

  Cos, Joan ^a   Villalba, Teresa ^a   Parra, Rafael ^a   Gallardo, Dominique ^a   Bilbao, Itxarone ^a   Margarit, Carlos ^a   Massuet, Lluís ^a  

^a BANC DE SANG I TEIXITS   (Spain)

Author keywords

Cell surface markers; Dendritic cells; FK506

Indexed keywords

CELL SURFACE MARKER; GAMMA INTERFERON; INTERLEUKIN 2; TACROLIMUS; IMMUNOSUPPRESSIVE AGENT; LEUKOCYTE ANTIGEN;

ALLOGRAFT; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CELL MATURATION; DENDRITIC CELL; DRUG EFFECT; HELPER CELL; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPHENOTYPING; ORGAN TRANSPLANTATION; SURVIVAL; CELL DIFFERENTIATION; CULTURE TECHNIQUE; CYTOLOGY; METHODOLOGY; MONOCYTE;

ANTIGENS, CD; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; DENDRITIC CELLS; HUMANS; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE AGENTS; MONOCYTES; TACROLIMUS;

EID: 0036075854     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. FK 506 for liver, kidney, and pancreas transplantation
2. The functional consequences of partial calcineurin inhibition in human peripheral blood mononuclear leucocytes
3. Immunosuppressive agents in clinical trials in transplantation
4. Murine liver allograft transplantation: Tolerance and donor cell chimerism
5. Reversal of transplantation immunity by liver grafting
6. Induction of immunological tolerance by porcine liver allografts
7. Frequent achievement of a drug-free state after orthotopic liver transplantation
8. Cell migration, chimerism, and graft acceptance
9. Cell migration and chimerism -a unifying concept in transplantation- with particular reference to HLA matching and tolerance induction
10. Donor cell chimerism permitted by immunosuppressive drugs: A new view of organ transplantation
11. Peripheral microchimerism in long-term cadaveric-kidney allograft recipients
12. Patterns of donor-type microchimerism after heart transplantation
13. Microchimerism, dendritic cell progenitors and transplantation tolerance
14. Identification of a novel cell type in peripheral lymphoid organs of mice I. Morphology, quantitation, tissue distribution
15. Dendritic cells and the control of immunity
16. Pathways of antigen processing and presentation
17. The dendritic cell system and its role in immunogenicity
18. Dendritic cells: From ontogenetic orphans to myelomonocytic descendants
19. Dendritic cells as antigen presenting cells in vivo
20. Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity
21. Dynamics of T lymphocyte responses: Intermediates, effectors, and memory cells
22. Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes
23. Glucocorticoids inhibit bioactive IL-12p70 production by in vitro-generated human dendritic cells without affecting their T cell stimulatory potential
24. Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3
25. Calcineurin acts in synergy with PMA to inactivate IkB/MAD3, an inhibitor of NF-kB
26. The actions of cyclosporine A and FK506 suggest a novel step in the activation of T lymphocytes
27. Tacrolimus (FK506) treatment of CD34+ hematopoietic progenitor cells promote the development of dendritic cells that drive CD4+ T cells toward Th2 responses
28. Ex vivo treatment of antigen-presenting cells with CTLA4lg and encephalitogenic peptide prevents experimental autoimmune encephalomyelitis in the Lewis rat
29. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor a
30. Are dendritic cells the key to liver transplant tolerance?
31. FK506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics
32. Effects of an immunosuppressant, FK506, on interleukin 1 alpha production by human macrophages and a macrophage-like cell line, U937
33. Evaluation of a novel "intelligent" dosing system for optimizing FK506 therapy
34. Recent advances in the study of dendritic cells and follicular dendritic cells
35. Dendritic cells: Specialized antigen presenting cells
36. The effect of calcineurin inhibitors and corticosteroids on the differentiation of human dendritic cells
37. Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells
38. + cells
39. The concept of type 1 and type 2 antigen-presenting cells
40. HLA class I molecule expression is up-regulated during maturation of dendritic cells, protecting them from natural killer cell-mediated lysis
41. Dendritic cells and the control of immunity
42. Dendritic cell tolerogenicity and prospects for dendritic cell based therapy of allograft rejection and autoimmunity
43. Inhibition of human dendritic cells functions by methylprednisolone
44. Coexpression of NF-κ B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-inuced, dendritic cell-T-cell syncytia
45. Dendritic cells survival and maturation are regulated by different signaling pathways
46. The NF-κB IκB proteins: New discoveries and insights
47. + monocytes as dendritic cell precursors: Diverse maturation-inducing pathways lead to common activation of NK-κ/RelB
48. Inhibition of nuclear translocation of transcription factor NF-κ B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
49. The Pl3 kinase, p38 SAP kinase, and NFκB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells
50. Role of NFκB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI
51. Effective antigen presentation by dendritic cells is NF-kappaB dependent: Coordinate regulation of MHC, co-stimulatory molecules and cytokines