Generation and functional characterization of human dendritic cells derived from CD34+ cells mobilized into peripheral blood: Comparison with bone marrow CD34+ cells

British Journal of Haematology

Volumn 101, Issue 4, 1998, Pages 756-765

  Ratta, Marina ^a   Rondelli, Damiano ^a   Fortuna, Alessandra ^a   Curti, Antonio ^a   Fogli, Miriam ^a   Fagnoni, Francesco ^b   Martinelli, Giovanni ^a   Terragna, Carolina ^a   Tura, Sante ^a   Lemoli, Roberto M ^a,c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c Inst Haematol Med Oncol S   (Italy)

Author keywords

CD34+ cells; Dendritic cells; Immunotherapy; Peripheral blood haemopoietic progenitors

Indexed keywords

CD1 ANTIGEN; CD14 ANTIGEN; CD34 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 4; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STEM CELL FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; COLONY FORMING UNIT; COLONY FORMING UNIT GM; CONTROLLED STUDY; DENDRITIC CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MIXED LYMPHOCYTE REACTION; NORMAL HUMAN; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; T LYMPHOCYTE;

ADJUVANTS, IMMUNOLOGIC; ANTIGENS, CD34; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; DENDRITIC CELLS; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-4; MEMBRANE PROTEINS; RECOMBINANT PROTEINS; STEM CELL FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 7144261710     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00771.x     Document Type: Article

References (36)

1. Bender, A., Sapp, M., Schuler, G., Steinman, R.M. & Bhardwaj, N. (1996) Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood. Journal of Immunological Methods, 196, 121-135.
2. + T cells. Journal of Clinical Investigation, 94, 797-801.
3. Boczkowski, D., Nair, K.S., Snyder, D. & Gilboa, E. (1996) Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. Journal of Experimental Medicine, 184, 465-472.
4. Caux, C., Dezutter-Dambuyant, S., Schmitt, D. & Bancherau, J. (1992) GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature. 360, 258-261.
5. Celluzzi, C.M., Mayordomo, J.L., Storkus, W.J., Lotze, M.T. & Falo, L.D. (1996) Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. Journal of Experimental Medicine, 183, 283-287.
6. + cells hematopoietic progenitor cells in cancer patients. European Journal of Immunology. 26, 595-600.
7. Flamand, V., Sornasse, T., Thielemans, K., Demanet, C., Bakkus, M., Bazin, H., Tielemans, F., Leo, O., Urbain, J. & Moser, M. (1994) Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo. European Journal of Immunology. 24, 605-610.
8. Guery, J.C. & Adorini, L. (1995) Dendritic cells are the most efficient in presenting endogenous naturally processed self-epitopes to class II-restricted T cells. Journal of Immunology. 154, 536-544.
9. Hsu, F.J., Benike, C., Fagnoni, F., Liles, T.M., Czerwinski, D., Taidi, B., Engleman, E.G. & Levy, R. (1996) Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nature Medicine, 2, 52-58.
10. Huang, A.Y.C., Golumbek, P., Ahmadzadeh, M., Jaffee, E., Pardoll, D. & Levitsky, H. (1994) Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Scienee, 264, 961-965.
11. Kwak, L.W., Taub, D.D., Duffey, P.L., Bensinger, W.I., Bryant, E.M., Reynolds, C.W. & Longo, D.L. (1995) Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor. Lancet, 345, 1016-1020.
12. Inaba, K., Metlay, J.P., Crowley, M.T. & Steinman, R.M. (1990) Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific MHC-restricted T cells in situ. Journal of Experimental Medicine, 172, 631-640.
13. + cells to remove circulating tumor cells. Blood, 87, 1625-1634.
14. + cells mobilized into peripheral blood of healthy donors by recombinant human granulocyte colony-stimulating factor. Blood, 89, 1189-1196.
15. Mayordomo, J.I., Zorina, T., Storkus, W.J., Zitvogel, L., Celluzzi, C., Falo, L.D., Melief, C., Ildstad, S.T., Kast, W.M., DeLeo, A.B. & Lotze, M.T. (1995) Bone marrow-derived dendritic cells pulsed with synthetic tumor peptides elicit protective and therapeutic antitumour immunity. Nature Medicine, 1, 1297-1302.
16. + CTLs from naive precursors. Journal of Immunology. 153, 996-1003.
17. Ogawa, M. (1993) Differentiation and proliferation of hematopoietic stem cells. Blood, 81, 2844-2853.
18. Paglia, P., Chiodoni, C., Rodolfo, M. & Colombo, M.P. (1996) Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo. Journal of Experimental Medicine, 183, 317-322.
19. Porgador, A., Snyder, D. & Gilboa, E. (1996) Induction of antitumor immunity using bone marrow-generated dendritic cells. Journal of Immunology, 156, 2918-2926.
20. Reeves, M.E., Royal, R.E., Lam, J.S., Rosenberg, S.A. & Hwu, P. (1996) Retroviral transduction of human dendritic cells with a tumor-associated antigen gene. Cancer Research, 56, 5672-5677.
21. Reid, C.D.L. (1997) The dendritic cell lineage in haemopoiesis. British Journal of Haematology, 96, 217-223.
22. + progenitors in human bone marrow. Journal of Immunology, 149, 2681-2688.
23. Romani, N., Gruner, S., Brang, D., Kampgen, E., Lenz, A., Trockenbacher, B., Konwalinka, G., Fritsch, P.O., Steinman, R.M. & Schuler, G. (1994) Proliferating dendritic cell progenitors in human blood. Journal of Experimental Medicine, 180, 83-93.
24. Romani, N., Reider, D., Heuer, M., Ebner, S., Kampgen, E., Eibl, B., Niederwieser, D. & Schuler, G. (1996) Generation of mature dendritic cells from human blood: an improved method with special regard to clinical applicability. Journal of Immunological Methods, 196, 137-151.
25. + hematopoietic cells. Blood, 88, 2619-2625.
26. + hematopoietic precursor cells. Blood, 87, 535-544.
27. Sallusto, F. & Lanzavecchia, A. (1994) Efficient presentation of soluble antigen by cultured dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis α. Journal of Experimental Medicine, 179, 1109-1118.
28. Schmitz, N., Linch, D.C., Dreger, P., Goldstone, A.H., Boogaerts, M.A., Ferrant, A., Demuynck, H.M.S., Link, H., Zander, A., Barge, A. & Borkett, K. (1996) Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation versus autologous bone marrow transplantation in lymphoma patients. Lancet, 347, 353-357.
29. + blood progenitors for anticancer therapy. Experimental Hematology, 23, 1463-1471.
30. Steinman, R.M. (1991) The dendritic cell system and its role in immunogenicity. Annual Review of Immunology, 9, 271-296.
31. Steinman, R,M. (1996) Dendritic cells and immune-based therapies. Experimental Hematalogy, 24, 859-862.
32. + hematopoietic progenitor cells. Blood, 87, 1292-1302.
33. + bone marrow precursors cultured with c-Kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-α. Journal of Immunology, 154, 5851-5861.
34. + cells. Bone Marrow Transplantation, 18, 997-1008.
35. + helper T cells. Journal of Experimental Medicine, 171, 1315-1320.
36. + bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor a. Journal of Experimental Medicine, 182, 1111-1120.