Nickel-specific CD4+ and CD8+ T cells display distinct migratory responses to chemokines produced during allergic contact dermatitis

Journal of Investigative Dermatology

Volumn 118, Issue 6, 2002, Pages 1052-1058

  Sebastiani, Silvia ^a   Albanesi, Cristina ^a   Nasorri, Francesca ^a   Girolomoni, Giampiero ^a   Cavani, Andrea ^a  

^a LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

Author keywords

Allergic contact dermatitis; Chemokines; Leukocyte trafficking; Skin

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CXCR3; HAPTEN; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NICKEL; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

ARTICLE; CELL TYPE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; KERATINOCYTE; LYMPHOCYTE CLONE; LYMPHOCYTE MIGRATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN ALLERGY; SUPERNATANT; T LYMPHOCYTE; TH2 CELL;

EID: 0036072232     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2002.01771.x     Document Type: Article

References (37)

1. + T cells in the lungs of patients with HIV infection and T-cell alveolitis
2. IL-4 enhances keratinocyte expression of CXCR3 agonistic chemokines
3. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases
4. Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells
5. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
6. + T lymphocytes primed by immunostimulating Langerhans cells
7. + T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene
8. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
9. + T cells
10. + T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses
11. Effector and regulatory T cells in allergic contact dermatitis
12. Migration kinetics and final destination of type 1 and type 2 effector cells predict protection against pulmonary virus infection
13. Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells
14. + T cell development from regulatory T helper to effector T helper cells alters the contact hypersensitivity response
15. The CXCR3 activating chemokines IP-10, Mig, and IP-9 are expressed in allergic but not in irritant patch test reactions
16. Immunophenotyping of the cellular infiltrate in the early elicitation phase of contact dermatitis in the skin of presensitized atopic individuals
17. Differential and sequential expression of multiple chemokines during elicitation of allergic contact hypersensitivity
18. Donorderived IP-10 initiates development of acute allograft rejection
19. + T cell-mediated contact hypersensitivity
20. The T cell chemoattractant IFN-inducible protein 10 is essential in host defense against viral-induced neurologic disease
21. CCR5 is characteristic of Th1 lymphocytes
22. Chemokines: Immunology's high impact factors
23. Chemokine receptor responses on T cells are achieved through the regulation of both receptor expression and signaling
24. Inhibition of T cell recruitment and cutaneous delayed-type hypersensitivity-induced inflammation with antibodies to monocyte chemoattractant protein-1
25. + T cells, and natural killer-type cells in human thymus
26. The biology of chemokines and their receptors
27. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells
28. Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance
29. + T lymphocytes with regulatory activity
30. + T cells in response to MIP-1a and MIP-1b
31. + T cell subsets against keratinocytes
32. T cell-mediated FAS-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis
33. Quantitative analysis of chemokine expression by dendritic cell subsets in vitro and in vivo
34. Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo
35. + type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity
36. + T cells
37. Chemokines: A new classification system and their role in immunity