The role of vascular endothelial growth factor (VEGF) in vasculogenesis, angiogenesis, and hematopoiesis in zebrafish development

Mechanisms of Development

Volumn 108, Issue 1-2, 2001, Pages 29-43

  Liang, Dong ^a   Chang, Jenny R ^b   Chin, Alvin J ^b,c   Smith, Alastair ^a   Kelly, Christina ^b   Weinberg, Eric S ^b   Ge, Ruowen ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Angiogenesis; Ectopic expression; flk1; gata1; Hematopoiesis; scl; tie1; Vascular endothelial growth factor; Vasculogenesis; Zebrafish

Indexed keywords

RNA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; AORTA; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; ERYTHROCYTE; EXON; GENE OVEREXPRESSION; HEMATOPOIESIS; MARKER GENE; MUTANT; NONHUMAN; NOTOCHORD; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMITE; VASCULARIZATION; ZEBRA FISH;

ANIMALS; BASE SEQUENCE; BLOOD VESSELS; DNA-BINDING PROTEINS; ENDOTHELIAL GROWTH FACTORS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; IN SITU HYBRIDIZATION; LYMPHOKINES; MUTATION; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN ISOFORMS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RNA, MESSENGER; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS; VERTEBRATES; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 0034830831     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00468-3     Document Type: Article

References (71)

1. Ontogenesis of hematopoietic sites in Brachydanio rerio (Hamilton-Buchanan) (Teleostei)
2. Dissecting hematopoiesis and disease using the zebrafish
3. 165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia
4. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
5. Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development
6. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
7. Imparied myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoform VEGF614 and VEGF188
8. A common precursor for hematopoietic and endothelial cells
9. VEGF mediates angioblast migration during development of the dorsal aorta in Xenopus
10. Neovascularization of the Xenopus embryo
11. Intra-embryonic hematopoietic cell migration during vertebrate development
12. Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization
13. Tall/SCL is expressed in endothelial progenitor cells/angioblasts and defines a dorsal-to-ventral gradient of vasculogenesis
14. Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
15. Vascularization of the mouse embryo: A study of flk-1, tek, tie, and VEGF expression during development
16. Ligand-dependent development of the endothelial and hemopoietic linages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2
17. Development of the hypochord and dorsal aorta in the zebrafish embryo (Danio rerio)
18. The biology of vascular endothelial growth factor
19. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
20. VEGF induces cardiovascular malformation and embryonic lethality
21. Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo
22. Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increased vascular permeability without alterations of embryonic pattern formation
23. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
24. Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice
25. Vessel patterning in the embryo of the zebrafish: Guidance by notochord
26. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
27. The SCL gene specifies hemangioblast development from early mesoderm
28. Erythroid expression of the 'helix-loop-helix' gene, SCL
29. SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain
30. Arterial gene transfer for therapeutic angiogenesis in patients with peripheral artery disease
31. The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis
32. A requirement for neuropilin-1 in embryonic vessel formation
33. Expression of two zebrafish orthodenticle-related genes in the embryonic brain
34. Cloning and characterization of vascular endothelial growth factor (VEGF) from zebrafish, Danio rerio
35. SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish
36. The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation
37. Hhex and Scl function in parallel to regulate early endothelial and blood differentiation in zebrafish
38. Isolation of the zebrafish homologues for the tie-1 and tie-2 endothelium-specific tyrosine kinases
39. Podocyte differentiation in the absence of endothelial cells as revealed in the zebrafish vascular mutant, cloche
40. Zebrafish no isthmus reveals a role for pax2.1 in tubule differentiation and patterning events in the pronephric primordia
41. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
42. Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression
43. Vascular endothelial growth factor-induced tumor angiogenesis and tumorigenicity in relation to metastasis in a HT1080 human fibrosarcoma cell model
44. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
45. Vascular endothelial growth factor (VEGF) and its receptors
46. Vascular and blood gene expression
47. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
48. La circulation sanguine chez l'embryon de brachydanio rerio (Teleosteens Cyprinidae)
49. Induction of angiogenesis by composite grafts of modified keratinocytes overexpressing VEGF driven by a keratin promoter
50. Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene
51. The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse
52. The hemangioblast - An elusive cell captured in culture
53. Failure of blood island formation and vasculogenesis in flk-1 deficient mice
54. A requirement for flk-1 in primitive and definitive hematopoesis and vasculogenesis
55. Absence of blood formation in mice lacking the T-cell leukemia oncoprotein tal-1/SCL
56. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
57. The zebrafish as a model system to study cardiovascular development
58. Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages
59. A role for notochord in axial vascular development revealed by analysis of phenotype and the expression of VEGFR-2 in zebrafish flh and ntl mutant embryos
60. Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia
61. A homeobox gene essential for zebrafish notochord development
62. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis
63. The human gene for vascular endothelial growth factor
64. Treatment of acute limb ischemia by intramuscular injection of vascular endothelial growth factor gene
65. Unsuspected role for the T-cell leukemia protein SCL/tal in vascular development
66. What guides early embryonic blood vessel formation?
67. Hematopoietic mutations in the zebrafish
68. VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of the chorioallantoic membrane
69. Flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors
70. KDR receptor: A key marker defining hematopoietic stem cells