Heat shock proteins and their clinical relevance

Acta Pharmaceutica

Volumn 52, Issue 2, 2002, Pages 71-82

  Barišić, Karmela ^a   Kopić, Jasminka ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Apoptosis; Clinical relevance of heat shock proteins; Cytoskeleton; Heat shock proteins

Indexed keywords

HEAT SHOCK PROTEIN;

ANTIGEN PRESENTATION; APOPTOSIS; CELL DEATH; CELL PROLIFERATION; CELL PROTECTION; CELLULAR IMMUNITY; CLINICAL CHEMISTRY; CYTOSKELETON; ENERGY METABOLISM; NONHUMAN; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FAMILY; REVIEW; TISSUE INJURY;

EID: 0036065788     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (93)

1. The heat shock proteins
2. The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner
3. Posttranslational quality control: Folding, refolding, and degrading proteins
4. Mammalian stress response: Cell physiology, structure/function of stress proteins, and implications for medicine and disease
5. Chaperons in cell cycle regulation and mitogenic signal transduction: A review
6. Role of the heat shock response and molecular chaperons in oncogenesis and cell death
7. Principles of protein folding in the cellular environment
8. Dogfish alpha-crystallin sequences. Comparison with small heat shock proteins and Schistosoma egg antigen
9. Role of the heat-shock response in the life and death of proteins
10. Proteasome and its novel endogenous activator in human platelets
11. Post-translational protein import and folding
12. Heat shock protein 70 kDa: Molecular biology, biochemistry, and physiology
13. Small heat shock proteins are molecular chaperons
14. Phosphorylation of the small heat shock-related protein, HSP20, in vascular smooth muscles is associated with changes in the macromolecular associations of HSP20
15. Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin
16. Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death
17. Small stress proteins: Chaperons that act as regulators of intracellular redox state and programmed cell death
18. Expression and function of the low molecular weight heat shock proteins
19. Supramolecular structure of the recombinant murine small heat shock protein hsp25
20. The expression of the growth-related 25 kDa protein (p25) of Ehrlich ascites tumor cells is increased by hyperthermic treatment (heat shock)
21. Alpha B-crystallin is a small heat shock protein
22. Molecular chaperons
23. Developmentally regulated transcription from Drosophila melanogaster chromosomal site 67B
24. Identification of a host protein necessary for bacteriophage morphogenesis (the groE gene product)
25. Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis
26. The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex
27. Purification and characterization of a heat-shock element binding protein from yeast
28. Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells
29. Role of the major heat shock proteins as molecular chaperons
30. Is hsp70 the cellular thermometer?
31. Cells in stress: Transcriptional activation of heat shock genes
32. Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1
33. Members of the 70-kilodalton heat shock protein family contain a highly conserved calmodulin-binding domain
34. Mutational analysis of the human HSP70 protein: Distinct domains for nucleolar localization and adenosine triphosphate binding
35. Regulation of the heat shock conjugate Hsc70 in the mammalian cell: The characterization of the anti-apoptotic protein BAG-1 provides novel insights
36. DnaJ dramatically stimulates ATP hydrolysis by DnaK: Insight into targeting of Hsp70 proteins to polypeptide substrates
37. Effect of bacteriophage M13 infection on phosphorylation of dnaK protein and other Escherichia coli proteins
38. Phosphorylation of the major heat shock protein of Dictyostelium discoideum
39. ADP-ribosylation of the Mr 83,000 stress-inducible and glucose-regulated protein in avian and mammalian cells: Modulation by heat shock and glucose starvation
40. Interconversion of three differentially modified and assembled forms of BiP
41. p75, a member of the heat shock protein family, undergoes tyrosine phosphorylation in response to oxidative stress
42. Methylations of 70,000-Da heat shock proteins in 3T3 cells: Alterations by arsenite treatment, by different stages of growth and by virus transformation
43. Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins
44. Evidence that the 90-kilodalton heat shock protein is associated with tubulin-containing complexes in L cell cytosol and in intact PtK cells
45. The 90-kDa molecular chaperon family: Structure, function, and clinical applications. A comprehensive review
46. The heat-shock response: Regulation and function of heat-shock proteins and molecular chaperons
47. Heat-shock protein hsp90 governs the activity of pp60v-src kinase
48. Modular folding and evidence for phosphorylation-induced stabilization of an hsp90-dependent kinase
49. A role for hsp90 in cell cycle control: Weel tyrosine kinase activity requires interaction with hsp90
50. The 90-kDa heat shock protein, HSP90, binds and protects casein kinase II from self-aggregation and enhances its kinase activity
51. Association between the mammalian 110,000-dalton heat-shock protein and nucleoli
52. Hsp104 is a highly conserved protein with two essential nucleotide-binding sites
53. HSP104 required for induced thermotolerance
54. Molecular chaperons and the cytoskeleton
55. Stabilization of actin filaments at early times after adenovirus infection and in heat-shocked cells
56. Heat shock proteins maintain the viability of ATP-deprived cells: What is the mechanism?
57. Changes in cell morphology and actin organization during heat shock in Dictyostelium discoideum: Does HSP70 play a role in acquired thermotolerance?
58. Aginactin, an agonist-regulated F-actin capping activity is associated with a HSC70 in Dictyostelium
59. The heat shock cognate protein from Dictyostelium affects actin polymerization through interaction with the actin-binding protein Cap32/34
60. Heat shock protein 90 (hsp90) binds in vitro to tubulin dimer and inhibits microtubule formation
61. Mutation of oncoprotein 18/stathmin identify tubulin-directed regulatory activities distinct from tubulin association
62. Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27
63. Mammalian protein RAP46: An interaction partner and modulator if 70 kDa heat shock proteins
64. Stress management - Heat shock protein-70 and the regulation of apoptosis
65. Heat-shock protein 70 antagonizes apoptosis-inducing factor
66. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation
67. Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance
68. Heat shock factors and the control of the stress response
69. Unfolding the role of chaperones and chaperonins in human disease
70. Heat shock proteins: The «Swiss Army Knife» vaccines against cancers and infections agents
71. The invertebrate phagocytic immunocyte: Clues to a common evolution of immune and neuroendocrine systems
72. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway
73. Heat shock and tissue protection
74. Maio, Heat shock proteins: Facts, thoughts, and dreams
75. Induction of heat shock protein 72 kDa expression is associated with attenuation of ischemia-reperfusion induced microvascular injury
76. Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery
77. Heat-shock response and limitation of tissue necrosis during occlusion/reperfusion in rabbit hearts
78. Heat shock protects WEHI-164 target cells from the cytolysis by tumor necrosis factors alpha and beta
79. Acute heat stress protects rats against endotoxin shock
80. Induction of heat stress proteins is associated with decreased mortality in an animal model of acute lung injury
81. Sodium arsenite induces heat shock protein-72 kilodalton expression in the lungs and protects rats against sepsis
82. Analysis of the specificity and mechanism of transcriptional activation of the human hsp 70 gene during infection by DNA viruses
83. Phagocytosis of Staphylococcus aureus induces a selective stress response in human monocytes-macrophages
84. Do heat shock proteins control the balance of T-cell regulation in inflammatory diseases?
85. Stress proteins as molecular markers of neurotoxicity
86. Immunotherapy of cancer using heat shock proteins
87. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides
88. Heat shock proteins refine the danger theory
89. Cancer vaccines: An update
90. Preventive and therapeutic effect of tumor derived heat shock protein gp96 in an experimental prostate cancer model
91. The consequences of expressing hsp70 in Drosophila cells at normal temperatures
92. The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression
93. Reciprocal expression of phosphoenolpyruvate carboxynase and acute phase genes