DNA-binding activities of the HilC and HilD virulence regulatory proteins of Salmonella enterica serovar Typhimurium

Journal of Bacteriology

Volumn 184, Issue 15, 2002, Pages 4148-4160

  Olekhnovich, Igor N ^a   Kadner, Robert J ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; DNA FRAGMENT; HYBRID PROTEIN; PROTEIN HILC; PROTEIN HILD; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; BINDING SITE; CELL INVASION; CONTROLLED STUDY; DNA FOOTPRINTING; DNA SEQUENCE; GEL ELECTROPHORESIS; GENE EXPRESSION; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PATHOGENICITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN FAMILY; SALMONELLA ENTERICA; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; DNA MUTATIONAL ANALYSIS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; PROMOTER REGIONS (GENETICS); SALMONELLA TYPHIMURIUM; SEQUENCE ALIGNMENT; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMATION, BACTERIAL; VIRULENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA; SALMONELLA ENTERICA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM;

EID: 0036064691     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.15.4148-4160.2002     Document Type: Article

References (47)

1. Salmonella SirA is a global regulator of genes mediating enteropathogenesis
2. Regulation of Salmonella enterica serovar Typhimurium invasion genes by csrA
3. hilA is a novel ompR/toxR family member that activates the expression of Salmonella typhimurium invasion genes
4. Co-ordinate regulation of Salmonella typhimurium invasion genes by environmental and regulatory factors is mediated by control of hilA expression
5. Transposition and fusion of the lac genes to selected promoters in E. coli using bacteriophage transposons
6. Preferential interaction of Salmonella typhimurium with mouse Peyer's patch M cells
7. The invasion-associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell
8. InvF is required for expression of genes encoding proteins secreted by the SPI1 type III secretion apparatus in Salmonella typhimurium
9. Molecular basis for the interaction of Salmonella with the intestinal mucosa
10. Anaerobiosis, type 1 fimbriae, and growth phase are factors that affect invasion of HEp-2 cells by Salmonella typhimurium
11. Hha is a negative modulator of transcription of hilA, the Salmonella enterica serovar Typhimurium invasion gene transcriptional activator
12. Diverse virulence traits underlying different clinical outcomes of Salmonella infection
13. The Salmonella typhimurium tyrosine phosphatase SptP is translocated into host cells and disrupts the actin cytoskeleton
14. Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells
15. Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling
16. DNase footprinting: A simple method for the detection of protein-DNA binding specificity
17. AraC/XylS family of transcriptional regulators
18. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
19. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of Peyer's patches
20. Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes
21. Selectivity of the Escherichia coli RNA polymerase E sigma 38 for overlapping promoters and ability to support CRP activation
22. The minus 35-recognition of Escherichia coli sigma 70 is inessential for initiation of transcription at an "extended minus 10" promoter
23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. The ability of Salmonella to enter mammalian cells is affected by bacterial growth state
25. Sequence specificity for DNA binding by Escherichia coli SoxS and Rob proteins
26. Improved vector system for constructing transcriptional fusions that ensures independent translation of lacZ
27. The cis requirements for transcriptional activation by HilA, a virulence determinant encoded on SPI1
28. AraC protein contacts asymmetric sites in the Escherichia coli araFGH promoter
29. Roles of hilC and hilD in regulation of hilA expression in Salmonella enterica serovar Typhimurium
30. Unraveling the mysteries of virulence gene regulation in Salmonella typhimurium
31. Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar Typhimurium
32. A 40-kb chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K-12 chromosome
33. Salmonella host cell invasion emerged by acquisition of a mosaic of separate genetic elements, including Salmonella pathogenicity island 1 (SPI1), SPI5, and sopE2
34. Invasion genes are not required for Salmonella enterica serovar Typhimurium to breach the intestinal epithelium: Evidence that Salmonella pathogenicity island 1 has alternative functions during infection
35. How AraC interacts specifically with its target DNAs
36. Separate contributions of UhpA and CAP to activation of transcription of the uhpT promoter of Escherichia coli
37. 70 subunits participate in transcription of the Escherichia coli uhpT promoter
38. Non-invasive Salmonella typhimurium mutants are avirulent because of an inability to enter and destroy M cells of ileal Peyer's patches
39. Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells
40. Two AraC/XylS family members can independently counteract the effect of repressing sequences upstream of the hilA promoter
41. AraC/XylS family members. HilC and HilD, directly bind and derepress the Salmonella typhimurium hilA promoter
42. Molecular pathogenesis of Salmonellae
43. Improved single and multicopy lac-based cloning vectors for protein and operon fusions
44. Electron microscope studies of experimental Salmonella infection. I. Penetration into the intestinal epithelium by Salmonella typhimurium
45. Fis, a DNA nucleoid-associated protein, is involved in Salmonella typhimurium SPI-1 invasion gene expression