Hha is a negative modulator of transcription of hilA, the Salmonella enterica serovar Typhimurium invasion gene transcriptional activator

Journal of Bacteriology

Volumn 183, Issue 22, 2001, Pages 6620-6629

  Fahlen, T F ^a   Wilson, R L ^a   Boddicker, J D ^a   Jones, B D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; REGULATOR PROTEIN HHA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HILA; UNCLASSIFIED DRUG;

ARTICLE; GENE EXPRESSION; MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; REPORTER GENE; SALMONELLA ENTERICA; TRANSCRIPTION INITIATION;

ANIMALS; BACTERIAL PROTEINS; CELLS, CULTURED; CHROMOSOMES, BACTERIAL; DNA, BACTERIAL; DNA-BINDING PROTEINS; DOWN-REGULATION; ESCHERICHIA COLI PROTEINS; GENES, REPORTER; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; SALMONELLA TYPHIMURIUM; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; VIRULENCE;

MURINAE; NEGIBACTERIA; SALMONELLA; SALMONELLA ENTERICA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; TYPHIMURIUM;

EID: 0034751820     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.22.6620-6629.2001     Document Type: Article

References (57)

1. Characterization of two novel regulatory genes affecting Salmonella invasion gene expression
2. hilA, is a novel ompR/toxR family member that activates the expression of Salmonella typhimurium invasion genes
3. Co-ordinate regulation of Salmonella typhimurium invasion genes by environmental and regulatory factors is mediated by control of hilA expression
4. Complementation of the hha mutation in Escherichia coli by the ymoA gene from Yersinia enterocolitica: Dependence on the gene dosage
5. A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells
6. Preferential interaction of Salmonella typhimurium with mouse Peyer's patch M cells
7. ymoA, a Yersinia enterocolitica chromosomal gene modulating the expression of virulence functions
8. Molecular basis of the interaction of Salmonella with the intestinal mucosa
9. Characterization of SprA, an AraC-like transcriptional regulator encoded within the Salmonella typhimurium pathogenicity island 1
10. Anaerohiosis, type 1 fimbriae, and growth phase are factors that affect invasion of HEp-2 cells by Salmonella typhimurium
11. Identification and characterization of mutants with increased expression of hilA, the invasion gene transcriptional activator of Salmonella typhimurium
12. Equilibria and kinetics of lac repressoroperator interactions by polyacrylamide gel electrophoresis
13. The Salmonella typhimurium tyrosine phosphatase SptP is translocated into host cells and disrupts the actin cytoskeleton
14. Interactions of bacteria with non-phagocytic cells
15. Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling
16. A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: Application to components of the Escherichia coli lactose operon regulatory, system
17. Chromosomal mutations that increase the production of a plasmid-encoded haemolysin in Escherichia coli
18. Cognate gene clusters govern invasion of host epithelial cells by Salmonella typhimurium and Shigella flexneri
19. Transcriptional regulation of Salmonella virulence: A PhoQ periplasmic domain mutation results in increased net phosphotransfer to PhoP
20. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells
21. Identification of a novel Salmonella invasion locus homologous to Shigella ipgDE
22. Type III protein secretion systems in bacterial pathogens of animals and plants
23. Multiple sequence alignment with Clustal X
24. Interactions of the invasive pathogens Salmonella typhimurium, Listeria monocytogenes, and Shigella flexneri with M cells and murine Peyer's patches
25. Transcriptional activation of Salmonella typhimurium invasion genes by a member of the phosphorylated response-regulator superfamily
26. Entry of microbes into the host: Using M cells to break the mucosal barrier
27. Identification and characterization of a Salmonella typhimurium oxygen-regulated gene required for bacterial internalization
28. Typhoid fever: Host immune response and Salmonella virulence determinants
29. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches
30. Invasion by Salmonella typhimurium is affected by the direction of flagellar rotation
31. A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium
32. Transcriptional organization and function of invasion genes within Salmonella pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes
33. The ability of Salmonella to enter mammalian cells is affected by bacterial growth state
34. Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants
35. Attenuated Salmonella as live oral vaccines against typhoid fever and as live vectors
36. Broad host range plasmids carrying the Escherichia coli lactose and galactose operons
37. Roles of hilC and hilD in regulation of hiL4 expression in Salmonella enterica serovar Typhimurium
38. Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar Typhimurium
39. Regulation of the Yersinia enterocolitica enterotoxin yst gene. Influence of growth phase, temperature, osmolarity, pH and bacterial host factors
40. Culture characteristics of four permanent lines of human cancer cells
41. The hha gene modulates haemolysin expression in Escherichia coli
42. Construction of a double hha hns mutant of Escherichia coli: Effect on DNA supercoiling and alpha-haemolysin production
43. Sequence, identification and effect on conjugation of the rmoA gene of plasmid R100-1
44. PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion genes: Evidence for a role in protein secretion
45. Non-invasive Sahnonella typhimurium mutants are avirulent because of an inability to enter and destroy M cells of ileal Peyer's patches
46. A HilA-independent pathway to Salmonella typhimurium invasion gene transcription
47. Acidification of phagosomes containing Salmonella typhimurium in murine macrophages
48. Two AraC/XyIS family members can independently counteract the effect of repressing sequences upstream of the hilA promoter
49. Anaerobic growth of Salmonella typhimurium results in increased uptake by Henle 407 epithelial and mouse peritoneal cells in vitro and repression of a major outer membrane protein
50. BCM Search Launcher - An integrated interface to molecular biology data base seach and analysis services available on the World Wide Web
51. Electron microscope studies of experimental Salmonella infection. I. Penetration into the intestinal epithelium by Salmonella typhimurium
52. CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2
53. Fis, a DNA nucleoid-associated protein, is involved in Salmonella typhimurium SPI-1 invasion gene expression
54. SopE, a secreted protein of Salmonella dublin, is translocated into the target eukaryotic cell via a sip-dependent mechanism and promotes bacterial entry
55. Experimental Salmonella typhimurium in calves