Kinetic properties of Kv4.3 and their modulation by KChIP2b

Biochemical and Biophysical Research Communications

Volumn 295, Issue 2, 2002, Pages 223-229

  Wang, Shimin ^a   Patel, Sangita P ^a   Qu, Yujie ^a   Hua, Ping ^a   Strauss, Harold C ^a   Morales, Michael J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Inactivation; KChIP; Pore; Potassium channel interacting proteins; Potassium channels

Indexed keywords

AMINO ACID; MUTANT PROTEIN; POTASSIUM CHANNEL; PROTEIN; PROTEIN KCHIP2B; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN STRUCTURE; REDUCTION; WILD TYPE;

ANIMALS; CALCIUM-BINDING PROTEINS; DNA, COMPLEMENTARY; KINETICS; KV CHANNEL-INTERACTING PROTEINS; MEMBRANE POTENTIALS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; SHAL POTASSIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS;

EID: 0036064133     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00658-7     Document Type: Article

References (42)

1. Voltage-gated potassium channels: From hyperexcitability to excitement
2. Cardiac ion channels
3. Electrophysiological and pharmacological correspondence between Kv4.2 current and rat cardiac transient outward current
4. Modulation of A-type potassium channels by a family of calcium sensors
5. Mouse DREAM/calsenilin/KChIP3: Gene structure, coding potential, and expression
6. Regulation of KChIP2 potassium channel β subunit gene expression underlies the gradient of transient outward current in canine and human ventricle
7. Tuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcription
8. Heterogeneous expression of KChIP2 isoforms in the ferret heart
9. Elimination of fast inactivation in Kv4 A-type potassium channels by an auxiliary subunit domain
10. + currents
11. + channel-interacting protein 2
12. Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating
13. Palmitoylation of KChIP splicing variants is required for efficient cell surface expression of Kv4.3 channels
14. to and confers susceptibility to ventricular tachycardia
15. Remodelling inactivation gating of Kv4 channels by KChIP1, a small-molecular-weight calcium-binding protein
16. 2+-binding protein, KChIP1, on two Kv4 subfamily members, Kv4.1 and Kv4.2
17. hKChIP2 is a functional modifier of hKv4.3 potassium channels: Cloning and expression of a short hKChIP2 splice variant
18. Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4
19. Functional interaction between KChIP1 and GFP-fused Kv4.3L co-expressed in HEK293 cells
20. Inactivation gating of Kv4 potassium channels, molecular interactions involving the inner vestibule of the pore
21. Kv4 channels exhibit modulation of closed-state inactivation in inside-out patches
22. Kinetic analysis of open- and closed-state inactivation transitions in human Kv4.2 A-type potassium channels
23. + channel (Kv1.4) expressed in Xenopus oocytes
24. Activation and inactivation kinetics of H-ERG expressed in Xenopus oocytes
25. Basic local alignment search tool
26. + channel subunit mRNAs in ventricles of renovascular hypertensive rats
27. + channel in ventricular muscle. A molecular correlate for the transient outward current
28. to: Further diversity by alternative mRNA splicing
29. + conduction and selectivity
30. + channel inactivation mediated by the concerted action of the cytoplasmic N- and C-terminal domains
31. + channels
32. + channel-modifying factor
33. Kvβ subunits increase expression of Kv4.3 channels by interacting with their C-termini
34. KChAP/Kvβ 1.2 interactions and their effects on cardiac Kv channel expression
35. +-currents
36. + currents in the mammalian myocardium by neuronal calcium sensor-1
37. Cell-surface targeting and clustering interactions between heterologously expressed PSD-95 and the Shal voltage-gated potassium channel, Kv4.2
38. Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin
39. Mink-related peptide1 associates with Kv4.2 and modulates its gating function: Potential role as β subunit of cardiac transient outward channel?