Kv4 channels exhibit modulation of closed-state inactivation in inside-out patches

Biophysical Journal

Volumn 81, Issue 2, 2001, Pages 867-883

  Beck, Edward J ^a   Covarrubias, Manuel ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; MEMBRANE POTENTIAL; NONHUMAN; POTASSIUM CURRENT; XENOPUS;

ANIMALIA;

EID: 0034902244     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75747-5     Document Type: Article

References (40)

1. Modulation of A-type potassium channels by a family of calcium sensors
2. + channel gating by protein phosphorylation: Structural switches of the inactivation gate
3. + channel
4. Modulation of Kv4 inactivation gating by a calcium binding protein KChIP-1
5. + channels
6. Selective modulation of closed-state inactivation in inside-out membrane patches expressing Kv4.1 channels
7. + channel. Insights into the molecular mechanism of protein kinase C action
8. The calcium-independent transient outward potassium current in isolated ferret ventricular myocytes
9. + channel
10. Slow repetitive activity from fast conductance changes in neurons
11. Voltage clamp studies of a transient outward membrane current in gastropod neural somata
12. 2+ channels by patch-cramming in Xenopus oocytes: Partial reversal by protein kinase A
13. Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate
14. + channel in ventricular muscle. A molecular correlate for the transient outward current
15. + channel inactivation gating by the cAMP-dependent protein kinase
16. + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons
17. + channels radically alters activation and inactivation
18. + channel inactivation mediated by the concerted action of the cytoplasmic N- and C-terminal domains
19. Inactivation gating of Kv4 potassium channels: Molecular interactions involving the inner vestibule of the pore
20. Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative Kv4.2 constructs
21. +] out accelerates inactivation of Shal-channels responsible for A-current in rat CA1 neurons
22. Inactivation of Kv2.1 channels
23. + channels must deactivate to recover from inactivation
24. Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 alpha-subunits
25. Patch cramming: Monitoring intracellular messengers in intact cells with membrane patches containing detector ion channels
26. Intracellular and extracellular amino acids that influence C-type inactivation and its modulation in a voltage-dependent potassium channel
27. A
28. + channels
29. + currents in mammalian cell lines and cardiac myocytes
30. + channel β subunits
31. + channels altered by presence of beta-subunit
32. 2+/calmodulin-dependent protein kinase
33. K(A) channels by cysteine oxidation
34. Identification of molecular components of A-type channels activating at subthreshold potentials
35. + channels operating at subthreshold potentials with unique expression in heart and brain
36. Voltage-dependent sodium channel function is regulated through membrane mechanics
37. + current mediated by the Kv4 channel regulates the generation of action potential in developing cerebellar granule cells
38. Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation
39. Gating of single non-Shaker A-type potassium channels in larval Drosophila neurons
40. Somatodendritic depolarization-activated potassium currents in rat neostriatal cholinergic interneurons are predominantly of the A type and attributable to coexpression of Kv4.2 and Kv4.1 subunits