DNA-PK inhibitor wortmannin enhances DNA damage induced by bleomycin in V79 Chinese hamster cells

Teratogenesis Carcinogenesis and Mutagenesis

Volumn 22, Issue 5, 2002, Pages 343-351

  Oliveira, Nuno G ^a,b   Castro, Matilde ^b,c   Rodrigues, António S ^a,d   Gil, Octávia M ^a,e   Toscano Rico, José M ^c   Rueff, José ^a  

^a UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^b UNIVERSITY OF LISBON   (Portugal)

^c INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^d UNIVERSIDADE LUSÓFONA DE HUMANIDADES E TECNOLOGIAS   (Portugal)

^e INSTITUTO TECNOLÓGICO E NUCLEAR   (Portugal)

Author keywords

Bleomycin; Cytokinesis block micronucleus assay; DNA dependent protein kinase (DNA PK); Non homologous end joining (NHEJ); V79 Chinese hamster cells; Wortmannin

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; DNA DEPENDENT PROTEIN KINASE; DNA DEPENDENT PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE KINASE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; WORTMANNIN; ANDROSTANE DERIVATIVE; ANTINEOPLASTIC ANTIBIOTIC; ENZYME INHIBITOR;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CHINESE HAMSTER; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINESIS; DNA DAMAGE; DRUG POTENTIATION; ENZYME ANALYSIS; ENZYME INHIBITION; FUNGAL METABOLISM; GENOTOXICITY; IONIZING RADIATION; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIZATION; ANIMAL; CELL DIVISION; CELL LINE; DOSE RESPONSE; HAMSTER; METABOLISM; MICRONUCLEUS;

ANDROSTADIENES; ANIMAL; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CELL DIVISION; CELL LINE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HAMSTERS; MICRONUCLEI; ANIMALS; CRICETINAE; MICRONUCLEI, CHROMOSOME-DEFECTIVE;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0036025187     PISSN: 02703211     EISSN: None     Source Type: Journal    
DOI: 10.1002/tcm.10029     Document Type: Article

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