메뉴 건너뛰기




Volumn 409, Issue 1, 1998, Pages 1-10

Bleomycin enhances random integration of transfected DNA into a human genome

Author keywords

Bleomycin; DNA strand break; Nonhomologous recombination; Random integration; Transfection

Indexed keywords

BLEOMYCIN; PLASMID DNA;

EID: 0031687619     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(98)00036-6     Document Type: Article
Times cited : (10)

References (64)
  • 1
    • 0002895728 scopus 로고
    • Illegitimate recombination in mammalian cells
    • in: R. Kucherlapati, G.R. Smith (Eds.), American Society for Microbiology, WA
    • D.B. Roth, J.H. Wilson, Illegitimate recombination in mammalian cells, in: R. Kucherlapati, G.R. Smith (Eds.), Genetic Recombination, American Society for Microbiology, WA, 1988, pp. 621-653.
    • (1988) Genetic Recombination , pp. 621-653
    • Roth, D.B.1    Wilson, J.H.2
  • 2
    • 0022261236 scopus 로고
    • Topological requirements for homologous recombination among DNA molecules transfected into mammalian cells
    • Wake C.T., Vernaleone F., Wilson J.H. Topological requirements for homologous recombination among DNA molecules transfected into mammalian cells. Mol. Cell. Biol. 5:1985;2080-2089.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 2080-2089
    • Wake, C.T.1    Vernaleone, F.2    Wilson, J.H.3
  • 4
    • 0028144408 scopus 로고
    • Characterization of DNA end joining in a mammalian cell nuclear extract: Junction formation is accompanied by nucleotide loss, which is limited and uniform but not site specific
    • Nicolás A.L., Young C.S.H. Characterization of DNA end joining in a mammalian cell nuclear extract: junction formation is accompanied by nucleotide loss, which is limited and uniform but not site specific. Mol. Cell. Biol. 14:1994;170-180.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 170-180
    • Nicolás, A.L.1    Young, C.S.H.2
  • 5
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbitts T.H. Chromosomal translocations in human cancer. Nature. 372:1994;143-149.
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbitts, T.H.1
  • 6
    • 0026335851 scopus 로고
    • Loss of constitutional heterozygosity in human cancer
    • Lasko D., Cavenee W. Loss of constitutional heterozygosity in human cancer. Annu. Rev. Genet. 25:1991;281-314.
    • (1991) Annu. Rev. Genet. , vol.25 , pp. 281-314
    • Lasko, D.1    Cavenee, W.2
  • 7
    • 37049182326 scopus 로고
    • Common mechanism of chromosome inversion in B- And T-cell tumors: Relevance to lymphoid development
    • Denny C.T., Hollis G.F., Hecht F., Morgan R., Link M.P., Smith S.D., Kirsch I.R. Common mechanism of chromosome inversion in B- and T-cell tumors: relevance to lymphoid development. Science. 234:1986;197-200.
    • (1986) Science , vol.234 , pp. 197-200
    • Denny, C.T.1    Hollis, G.F.2    Hecht, F.3    Morgan, R.4    Link, M.P.5    Smith, S.D.6    Kirsch, I.R.7
  • 8
    • 0024411328 scopus 로고
    • Recent progress in understanding mechanisms of mammalian DNA amplification
    • Strark G.R., Debatisse M., Giulotto E., Wahl G.M. Recent progress in understanding mechanisms of mammalian DNA amplification. Cell. 57:1989;901-908.
    • (1989) Cell , vol.57 , pp. 901-908
    • Strark, G.R.1    Debatisse, M.2    Giulotto, E.3    Wahl, G.M.4
  • 9
    • 0021827069 scopus 로고
    • Relative rates of homologous and nonhomologous recombination in transfected DNA
    • Roth D.B., Wilson J.H. Relative rates of homologous and nonhomologous recombination in transfected DNA. Proc. Natl. Acad. Sci. U.S.A. 82:1985;3355-3359.
    • (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 3355-3359
    • Roth, D.B.1    Wilson, J.H.2
  • 10
    • 0024328536 scopus 로고
    • Altering the genome by homologous recombination
    • Capecchi M.R. Altering the genome by homologous recombination. Science. 244:1989;1288-1292.
    • (1989) Science , vol.244 , pp. 1288-1292
    • Capecchi, M.R.1
  • 11
    • 0025343532 scopus 로고
    • Recombination events during integration of transfected DNA into normal human cells
    • Murnane J.P., Yezzi M.J., Young B.R. Recombination events during integration of transfected DNA into normal human cells. Nucleic Acids Res. 18:1990;2733-2738.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 2733-2738
    • Murnane, J.P.1    Yezzi, M.J.2    Young, B.R.3
  • 12
    • 0019353199 scopus 로고
    • Transforming DNA integrates into the host chromosome
    • Robins D.M., Ripley S., Henderson A.S., Axel R. Transforming DNA integrates into the host chromosome. Cell. 23:1981;29-39.
    • (1981) Cell , vol.23 , pp. 29-39
    • Robins, D.M.1    Ripley, S.2    Henderson, A.S.3    Axel, R.4
  • 13
    • 0030040266 scopus 로고    scopus 로고
    • Effects of DNA topoisomerase inhibitors on nonhomologous and homologous recombination in mammalian cells
    • Aratani Y., Andoh T., Koyama H. Effects of DNA topoisomerase inhibitors on nonhomologous and homologous recombination in mammalian cells. Mutat. Res. 362:1996;181-191.
    • (1996) Mutat. Res. , vol.362 , pp. 181-191
    • Aratani, Y.1    Andoh, T.2    Koyama, H.3
  • 14
    • 0030482863 scopus 로고    scopus 로고
    • DNA topoisomerase II inhibitors enhance random integration of transfected vectors into human chromosomes
    • Fujimaki F., Aratani Y., Fujisawa S., Motomura S., Okubo T., Koyama H. DNA topoisomerase II inhibitors enhance random integration of transfected vectors into human chromosomes. Somat. Cell Mol. Genet. 22:1996;279-290.
    • (1996) Somat. Cell Mol. Genet. , vol.22 , pp. 279-290
    • Fujimaki, F.1    Aratani, Y.2    Fujisawa, S.3    Motomura, S.4    Okubo, T.5    Koyama, H.6
  • 15
    • 0021891888 scopus 로고
    • DNA topoisomerases
    • Wang J.C. DNA topoisomerases. Annu. Rev. Biochem. 54:1985;665-697.
    • (1985) Annu. Rev. Biochem. , vol.54 , pp. 665-697
    • Wang, J.C.1
  • 16
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumor drugs
    • Liu L.F. DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58:1989;351-375.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 351-375
    • Liu, L.F.1
  • 17
    • 0011173714 scopus 로고
    • DNA topoisomerase II mutant of Saccharomyces cerevisiae: Topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication
    • DiNardo S., Voelkel-Meiman K., Sternglanz R. DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication. Proc. Natl. Acad. Sci. U.S.A. 81:1984;2616-2620.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 2616-2620
    • Dinardo, S.1    Voelkel-Meiman, K.2    Sternglanz, R.3
  • 18
    • 0022400533 scopus 로고
    • DNA topoisomerase II is required at the time of mitosis in yeast
    • Holm C., Goto T., Wang J.C., Botstein D. DNA topoisomerase II is required at the time of mitosis in yeast. Cell. 41:1985;553-563.
    • (1985) Cell , vol.41 , pp. 553-563
    • Holm, C.1    Goto, T.2    Wang, J.C.3    Botstein, D.4
  • 19
    • 0023651332 scopus 로고
    • DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe
    • Uemura U., Ohkura H., Adachi Y., Morino K., Shiozaki K., Yanagida M. DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe. Cell. 50:1987;917-925.
    • (1987) Cell , vol.50 , pp. 917-925
    • Uemura, U.1    Ohkura, H.2    Adachi, Y.3    Morino, K.4    Shiozaki, K.5    Yanagida, M.6
  • 20
    • 0024299511 scopus 로고
    • Transcription-dependent DNA supercoiling in yeast DNA topoisomerase mutants
    • Brill S.J., Sternglanz R. Transcription-dependent DNA supercoiling in yeast DNA topoisomerase mutants. Cell. 54:1988;403-411.
    • (1988) Cell , vol.54 , pp. 403-411
    • Brill, S.J.1    Sternglanz, R.2
  • 21
    • 0024277974 scopus 로고
    • Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II
    • Christman M.F., Dietrich F.S., Fink G.R. Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Cell. 55:1988;413-425.
    • (1988) Cell , vol.55 , pp. 413-425
    • Christman, M.F.1    Dietrich, F.S.2    Fink, G.R.3
  • 22
    • 0024392077 scopus 로고
    • A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings
    • Kim R.A., Wang J.C. A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings. Cell. 57:1989;975-985.
    • (1989) Cell , vol.57 , pp. 975-985
    • Kim, R.A.1    Wang, J.C.2
  • 23
    • 0025966711 scopus 로고
    • Chromosome assembly in vitro: Topoisomerase II is required for condensation
    • Adachi Y., Luke M., Laemmli U.K. Chromosome assembly in vitro: topoisomerase II is required for condensation. Cell. 64:1991;137-148.
    • (1991) Cell , vol.64 , pp. 137-148
    • Adachi, Y.1    Luke, M.2    Laemmli, U.K.3
  • 24
    • 0012416841 scopus 로고
    • DNA topoisomerase-mediated illegitimate recombination
    • in: N. Cozzarelli, J.C. Wang (Eds.), Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • H. Ikeda, DNA topoisomerase-mediated illegitimate recombination, in: N. Cozzarelli, J.C. Wang (Eds.), DNA Topoisomerase, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1990, pp. 341-359.
    • (1990) DNA Topoisomerase , pp. 341-359
    • Ikeda, H.1
  • 25
    • 0024997668 scopus 로고
    • The role of DNA topoisomerases in recombination and genome stability: A double-edged sword?
    • Wang J.C., Caron P.R., Kim R.A. The role of DNA topoisomerases in recombination and genome stability: A double-edged sword? Cell. 62:1990;403-406.
    • (1990) Cell , vol.62 , pp. 403-406
    • Wang, J.C.1    Caron, P.R.2    Kim, R.A.3
  • 26
    • 0025008740 scopus 로고
    • The DNA gyrase of Escherichia coli participates in the formation of a spontaneous deletion by recA-independent recombination in vivo
    • Miura-Masuda A., Ikeda H. The DNA gyrase of Escherichia coli participates in the formation of a spontaneous deletion by recA-independent recombination in vivo. Mol. Gen. Genet. 220:1990;345-352.
    • (1990) Mol. Gen. Genet. , vol.220 , pp. 345-352
    • Miura-Masuda, A.1    Ikeda, H.2
  • 27
    • 0022667061 scopus 로고
    • Bacteriophage T4 DNA topoisomerase mediates illegitimate recombination in vitro
    • Ikeda H. Bacteriophage T4 DNA topoisomerase mediates illegitimate recombination in vitro. Proc. Natl. Acad. Sci. U.S.A. 83:1986;922-926.
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 922-926
    • Ikeda, H.1
  • 28
    • 0020143901 scopus 로고
    • Illegitimate recombination mediated in vitro by DNA gyrase of Escherichia coli: Structure of recombinant DNA molecules
    • Ikeda H., Aoki K., Naito A. illegitimate recombination mediated in vitro by DNA gyrase of Escherichia coli: structure of recombinant DNA molecules. Proc. Natl. Acad. Sci. U.S.A. 79:1982;3724-3728.
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 3724-3728
    • Ikeda, H.1    Aoki, K.2    Naito, A.3
  • 29
    • 0024121519 scopus 로고
    • Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro
    • Bae Y.-S., Kawasaki I., Ikeda H., Liu L.F. Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro. Proc. Natl. Acad. Sci. U.S.A. 85:1988;2076-2080.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 2076-2080
    • Bae, Y.-S.1    Kawasaki, I.2    Ikeda, H.3    Liu, L.F.4
  • 30
    • 0026694614 scopus 로고
    • Intrinsic intermolecular DNA ligation activity of eukaryotic topoisomerase: II. Potential roles in recombination
    • Gale K.C., Osheroff N. Intrinsic intermolecular DNA ligation activity of eukaryotic topoisomerase: II. Potential roles in recombination. J. Biol. Chem. 267:1992;12090-12097.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12090-12097
    • Gale, K.C.1    Osheroff, N.2
  • 31
    • 0021333644 scopus 로고
    • Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide
    • Nelson E.M., Tewey K.M., Liu L.F. Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide. Proc. Natl. Acad. Sci. U.S.A. 81:1984;1361-1365.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 1361-1365
    • Nelson, E.M.1    Tewey, K.M.2    Liu, L.F.3
  • 32
    • 0017548298 scopus 로고
    • DNA double-strand breaks and alkali-labile bonds produced by bleomycin
    • Povirk L.F., Wübker W., Köhnlein W., Hutchinson F. DNA double-strand breaks and alkali-labile bonds produced by bleomycin. Nucleic Acids Res. 4:1977;3573-3580.
    • (1977) Nucleic Acids Res. , vol.4 , pp. 3573-3580
    • Povirk, L.F.1    Wübker, W.2    Köhnlein, W.3    Hutchinson, F.4
  • 33
    • 0022981317 scopus 로고
    • The DNA cleavage mechanism of iron-bleomycin: Kinetic resolution of strand scission from base propenal release
    • Burger R.M., Projan S.J., Horwitz S.B., Peisach J. The DNA cleavage mechanism of iron-bleomycin: kinetic resolution of strand scission from base propenal release. J. Biol. Chem. 261:1986;15955-15959.
    • (1986) J. Biol. Chem. , vol.261 , pp. 15955-15959
    • Burger, R.M.1    Projan, S.J.2    Horwitz, S.B.3    Peisach, J.4
  • 34
    • 0024396338 scopus 로고
    • Structure of bleomycin-induced DNA double-strand breaks: Predominance of blunt ends and single-base 5′ extensions
    • Povirk L.F., Han Y.-H., Steighner R.J. Structure of bleomycin-induced DNA double-strand breaks: predominance of blunt ends and single-base 5′ extensions. Biochemistry. 28:1989;5808-5814.
    • (1989) Biochemistry , vol.28 , pp. 5808-5814
    • Povirk, L.F.1    Han, Y.-H.2    Steighner, R.J.3
  • 35
    • 0025114681 scopus 로고
    • Bleomycin-induced DNA lesions at mutational hot spots: Implications for the mechanism of double-strand cleavage
    • Steighner R.J., Povirk L.F. Bleomycin-induced DNA lesions at mutational hot spots: Implications for the mechanism of double-strand cleavage. Proc. Natl. Acad. Sci. U.S.A. 87:1990;8350-8354.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 8350-8354
    • Steighner, R.J.1    Povirk, L.F.2
  • 36
    • 0027991713 scopus 로고
    • Electrospray mass spectrometry of iron bleomycin: Demonstration that activated bleomycin is a ferric peroxide complex
    • Sam J.W., Tang X.-J., Peisach J. Electrospray mass spectrometry of iron bleomycin: Demonstration that activated bleomycin is a ferric peroxide complex. J. Am. Chem. Soc. 116:1994;5250-5256.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 5250-5256
    • Sam, J.W.1    Tang, X.-J.2    Peisach, J.3
  • 37
    • 0028254320 scopus 로고
    • Polynucleotide recognition and degradation by bleomycin
    • Kane S.A., Hecht S.M. Polynucleotide recognition and degradation by bleomycin. Prog. Nucl. Acid Res. Mol. Biol. 49:1994;313-352.
    • (1994) Prog. Nucl. Acid Res. Mol. Biol. , vol.49 , pp. 313-352
    • Kane, S.A.1    Hecht, S.M.2
  • 38
    • 0000594666 scopus 로고
    • Bleomycins: Mechanism of polynucleotide recognition and oxidative degradation
    • in: S. Neidle, M.J. Waring (Eds.), Macmillan, Basingstoke and London
    • A. Natrajan, S.M. Hecht, Bleomycins: Mechanism of polynucleotide recognition and oxidative degradation, in: S. Neidle, M.J. Waring (Eds.), Molecular Aspects of Anticancer Drug-DNA Interactions, Vol. 2, Macmillan, Basingstoke and London, 1994, pp. 197-242.
    • (1994) Molecular Aspects of Anticancer Drug-DNA Interactions , vol.2 , pp. 197-242
    • Natrajan, A.1    Hecht, S.M.2
  • 39
    • 0002746148 scopus 로고    scopus 로고
    • Bleomycins: A structural model for specificity, binding, and double strand cleavage
    • Stubbe J., Kozarich J.W., Wu W., Vanderwall D.E. Bleomycins: A structural model for specificity, binding, and double strand cleavage. Acc. Chem. Res. 29:1996;322-330.
    • (1996) Acc. Chem. Res. , vol.29 , pp. 322-330
    • Stubbe, J.1    Kozarich, J.W.2    Wu, W.3    Vanderwall, D.E.4
  • 40
    • 0019989719 scopus 로고
    • Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter
    • Southern P.J., Berg P. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Mol. Appl. Genet. 1:1982;327-341.
    • (1982) J. Mol. Appl. Genet. , vol.1 , pp. 327-341
    • Southern, P.J.1    Berg, P.2
  • 42
    • 0031550237 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of the mouse DNA topoisomerase IIα gene promoter
    • Adachi N., Kobayashi M., Koyama H. Cell cycle-dependent regulation of the mouse DNA topoisomerase IIα gene promoter. Biochem. Biophys. Res. Commun. 230:1997;105-109.
    • (1997) Biochem. Biophys. Res. Commun. , vol.230 , pp. 105-109
    • Adachi, N.1    Kobayashi, M.2    Koyama, H.3
  • 43
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa H., Yamamura K., Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene. 108:1991;193-200.
    • (1991) Gene , vol.108 , pp. 193-200
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 44
    • 0030580947 scopus 로고    scopus 로고
    • The comet assay: Mechanisms and technical considerations
    • Klaude M., Eriksson S., Nygren J., Ahnström G. The comet assay: mechanisms and technical considerations. Mutat. Res. 363:1996;89-96.
    • (1996) Mutat. Res. , vol.363 , pp. 89-96
    • Klaude, M.1    Eriksson, S.2    Nygren, J.3    Ahnström, G.4
  • 45
    • 0030002162 scopus 로고    scopus 로고
    • Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay
    • Kasamatsu K., Kohda K., Kawazoe Y. Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay. Mutat. Res. 369:1996;1-6.
    • (1996) Mutat. Res. , vol.369 , pp. 1-6
    • Kasamatsu, K.1    Kohda, K.2    Kawazoe, Y.3
  • 46
    • 0021712074 scopus 로고
    • The effect of X-rays and ultraviolet light on DNA-mediated gene transfer in mammalian cells
    • Debenham P.G., Webb M.B.T. The effect of X-rays and ultraviolet light on DNA-mediated gene transfer in mammalian cells. Int. J. Radiat. Biol. 46:1984;555-568.
    • (1984) Int. J. Radiat. Biol. , vol.46 , pp. 555-568
    • Debenham, P.G.1    Webb, M.B.T.2
  • 47
    • 0021752388 scopus 로고
    • Stimulation of DNA-mediated transformation by UV irradiation of recipient (mouse FM3A) cells
    • Nagata Y., Takagi H., Morita T., Oishi M. Stimulation of DNA-mediated transformation by UV irradiation of recipient (mouse FM3A) cells. J. Cell. Physiol. 121:1984;453-457.
    • (1984) J. Cell. Physiol. , vol.121 , pp. 453-457
    • Nagata, Y.1    Takagi, H.2    Morita, T.3    Oishi, M.4
  • 48
    • 0021922957 scopus 로고
    • UV stimulation of DNA-mediated transformation of human cells
    • Van Duin M., Westerveld A., Hoeijmaker J.H.J. UV stimulation of DNA-mediated transformation of human cells. Mol. Cell. Biol. 5:1985;734-741.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 734-741
    • Van Duin, M.1    Westerveld, A.2    Hoeijmaker, J.H.J.3
  • 49
    • 0021779765 scopus 로고
    • Enhancement of genetic transformation frequencies of mammalian cell cultures by damage to the cell DNA
    • Postel E.H. Enhancement of genetic transformation frequencies of mammalian cell cultures by damage to the cell DNA. Mol. Gen. Genet. 201:1985;136-139.
    • (1985) Mol. Gen. Genet. , vol.201 , pp. 136-139
    • Postel, E.H.1
  • 51
    • 0025760663 scopus 로고
    • A shuttle vector for analysis of illegitimate recombination in mammalian cells: Effects of DNA topoisomerase inhibitors on deletion frequency
    • Bae Y.-S., Chiba M., Ohira M., Ikeda H. A shuttle vector for analysis of illegitimate recombination in mammalian cells: effects of DNA topoisomerase inhibitors on deletion frequency. Gene. 101:1991;285-289.
    • (1991) Gene , vol.101 , pp. 285-289
    • Bae, Y.-S.1    Chiba, M.2    Ohira, M.3    Ikeda, H.4
  • 52
    • 0027445706 scopus 로고
    • Integration of simian virus 40 into cellular DNA occurs at or near topoisomerase II cleavage hot spots induced by VM-26 (teniposide)
    • Bodley A.L., Huang H.-C., Yu C., Liu L.F. Integration of simian virus 40 into cellular DNA occurs at or near topoisomerase II cleavage hot spots induced by VM-26 (teniposide). Mol. Cell. Biol. 13:1993;6190-6200.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6190-6200
    • Bodley, A.L.1    Huang, H.-C.2    Yu, C.3    Liu, L.F.4
  • 53
    • 0029047860 scopus 로고
    • DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors
    • Russell D.W., Alexander I.E., Miller A.D. DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors. Proc. Natl. Acad. Sci. U.S.A. 92:1995;5719-5723.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 5719-5723
    • Russell, D.W.1    Alexander, I.E.2    Miller, A.D.3
  • 54
    • 0029655281 scopus 로고    scopus 로고
    • High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genome
    • Merrihew R.V., Marburger K., Pennington S.L., Roth D.B., Wilson J.H. High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genome. Mol. Cell. Biol. 16:1996;10-18.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 10-18
    • Merrihew, R.V.1    Marburger, K.2    Pennington, S.L.3    Roth, D.B.4    Wilson, J.H.5
  • 55
    • 0026425619 scopus 로고
    • Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives
    • Tanabe K., Ikegami Y., Ishida R., Andoh T. Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives. Cancer Res. 51:1991;4903-4908.
    • (1991) Cancer Res. , vol.51 , pp. 4903-4908
    • Tanabe, K.1    Ikegami, Y.2    Ishida, R.3    Andoh, T.4
  • 56
    • 0026425654 scopus 로고
    • Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: Mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors
    • Ishida R., Miki T., Narita T., Yui R., Sato M., Utsumi K.R., Tanabe K., Andoh T. Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors. Cancer Res. 51:1991;4909-4916.
    • (1991) Cancer Res. , vol.51 , pp. 4909-4916
    • Ishida, R.1    Miki, T.2    Narita, T.3    Yui, R.4    Sato, M.5    Utsumi, K.R.6    Tanabe, K.7    Andoh, T.8
  • 58
    • 0027965213 scopus 로고
    • Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events
    • Ishida R., Sato M., Narita T., Utsumi K.R., Nishimoto T., Morita T., Nagata H., Andoh T. Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events. J. Cell Biol. 26:1994;1341-1351.
    • (1994) J. Cell Biol. , vol.26 , pp. 1341-1351
    • Ishida, R.1    Sato, M.2    Narita, T.3    Utsumi, K.R.4    Nishimoto, T.5    Morita, T.6    Nagata, H.7    Andoh, T.8
  • 59
    • 0029162684 scopus 로고
    • Deletion at short direct repeats and base substitutions are characteristic mutations for bleomycin-induced double- And single-strand breaks, respectively, in a human shuttle vector system
    • Dar M.D., Jorgensen T.J. Deletion at short direct repeats and base substitutions are characteristic mutations for bleomycin-induced double- and single-strand breaks, respectively, in a human shuttle vector system. Nucleic Acids Res. 23:1995;3224-3230.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3224-3230
    • Dar, M.D.1    Jorgensen, T.J.2
  • 60
    • 0028065121 scopus 로고
    • Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome
    • Phillips J.W., Morgan W.F. Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome. Mol. Cell. Biol. 14:1994;5794-5803.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5794-5803
    • Phillips, J.W.1    Morgan, W.F.2
  • 61
    • 0028237305 scopus 로고
    • Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
    • Rouet P., Smih F., Jasin M. Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 91:1994;6064-6068.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 6064-6068
    • Rouet, P.1    Smih, F.2    Jasin, M.3
  • 62
    • 0028577296 scopus 로고
    • Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells
    • Godwin A.R., Bollag R.J., Christie D.M., Liskay R.M. Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells. Proc. Natl. Acad. Sci. U.S.A. 91:1994;12554-12558.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 12554-12558
    • Godwin, A.R.1    Bollag, R.J.2    Christie, D.M.3    Liskay, R.M.4
  • 63
    • 0028919608 scopus 로고
    • Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae
    • Choulika A., Perrin A., Dujon B., Nicolas J.-F. Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol. Cell. Biol. 15:1995;1968-1973.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1968-1973
    • Choulika, A.1    Perrin, A.2    Dujon, B.3    Nicolas, J.-F.4
  • 64
    • 0031032549 scopus 로고    scopus 로고
    • Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination
    • Sargent R.G., Brenneman M.A., Wilson J.H. Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol. Cell. Biol. 16:1997;267-277.
    • (1997) Mol. Cell. Biol. , vol.16 , pp. 267-277
    • Sargent, R.G.1    Brenneman, M.A.2    Wilson, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.