Arabidopsis RPP4 is a member of the RPP5 multigene family of TIR-NB-LRR genes and confers downy mildew resistance through multiple signalling components

Plant Journal

Volumn 29, Issue 4, 2002, Pages 439-451

  Van Der Biezen, Erik A ^a,b   Freddie, Cecilie T ^a,c   Kahn, Katherine ^a   Parker, Jane E ^a,d   Jones, Jonathan D G ^a  

^a SAINSBURY LABORATORY   (United Kingdom)

^b SANOFI   (France)

^c Institute of Biology   (Denmark)

^d MAX PLANCK INSTITUTE FOR PLANT BREEDING RESEARCH   (Germany)

Author keywords

Arabidopsis; Defence signalling pathway; Peronospora parasitica; RPP4; TIR NB LRR

Indexed keywords

GENES; PROTEINS;

COTYLEDONS;

PLANTS (BOTANY);

ARABIDOPSIS; EMBRYOPHYTA; FUNGI; HYALOPERONOSPORA PARASITICA; PERONOSPORA; PERONOSPORA FARINOSA; TEREBRANTIA;

ARABIDOPSIS PROTEIN; DNA BINDING PROTEIN; EDS1 PROTEIN, ARABIDOPSIS; NDR1 PROTEIN, ARABIDOPSIS; RPP5 PROTEIN, ARABIDOPSIS; TRANSCRIPTION FACTOR; VEGETABLE PROTEIN;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARTICLE; COMPARATIVE STUDY; GENE; GENE EXPRESSION REGULATION; GENETIC COMPLEMENTATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; INNATE IMMUNITY; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MULTIGENE FAMILY; OOMYCETES; PHYLOGENY; PLANT DISEASE; PLANT LEAF; PROTEIN BINDING; RESTRICTION MAPPING; SIGNAL TRANSDUCTION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARABIDOPSIS PROTEINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, PLANT; GENES, PLANT; GENETIC COMPLEMENTATION TEST; IMMUNITY, NATURAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OOMYCETES; PHYLOGENY; PLANT DISEASES; PLANT LEAVES; PLANT PROTEINS; PROTEIN BINDING; RESTRICTION MAPPING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0036008975     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0960-7412.2001.01229.x     Document Type: Article

References (45)

1. Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene-mediated signaling pathways in Arabidopsis
2. Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana
3. RPP13 is a simple locus in Arabidopsis thaliana for alleles that specify downy mildew resistance to different avirulence determinants in Peronospora parasitica
4. Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasitica avirulence determinants
5. The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats
6. NDR1, a locus of Arabidopsis thaliana that is required for disease resistance to both a bacterial and a fungal pathogen
7. NDR1, a pathogen-induced component required for Arabidopsis disease resistance
8. Floral dip: A simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana
9. Members of the Arabidopsis HRT/RPP8 family of resistance genes confer resistance to both viral and oomycete pathogens
10. A central role of salicylic acid in plant disease resistance
11. The identification of regions in alleles of the flax rust resistance gene L that determine differences in gene-for-gene specificity
12. EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis, has homology to eukaryotic lipases
13. Interplay of signaling pathways in plant disease resistance
14. Direct interaction between the Arabidopsis disease resistance signaling proteins, EDS1 and PAD4
15. Requirement of salicylic acid for the induction of systemic acquired resistance
16. Phytoalexin-deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes contribute to downy mildew resistance
17. Phenotypic and genotypic characterization of interactions between isolates of Peronospora parasitica and accessions of Arabidopsis thalliana
18. Direct interaction of resistance gene and avirulence gene products confers rice blast resistance
19. Arabidopsis thaliana PAD4 encodes a lipase-like gene that is important for salicylic acid signaling
20. The role of leucine-rich repeat proteins in plant defences
21. A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers
22. Benzothiadiazole induces disease resistance in Arabidopsis by activation of the systemic acquired resistance signal transduction pathway
23. Regions outside of the leucine-rich repeats of flax rust resistance proteins play a role in specificity determination
24. Production of salicylic acid precursors is a major function of phenylalanine ammonia-lyase in the resistance of Arabidopsis to Peronospora parasitica
25. Arabidopsis dth9 mutation identifies a gene involved in regulating disease susceptibility without affecting salicylic acid-dependent responses
26. Intragenic recombination and diversifying selection contribute to the evolution of downy mildew resistance at the RPP8 locus of Arabidopsis
27. Downy mildew (Peronospora parasitica) resistance genes in Arabidopsis vary in functional requirements for NDR1, EDS1, NPR1 and salicylic acid accumulation
28. Plant disease resistance genes encode members of an ancient and diverse protein family within the nucleotide-binding superfamily
29. Salicylic acid induction-deficient mutants of Arabidopsis express PR-2 and PR-5 and accumulate high levels of camalexin after pathogen inoculation
30. Pronounced intraspecific haplotype divergence at the RPP5 complex disease resistance locus of Arabidopsis
31. Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants
32. Characterization of eds1, a mutation in Arabidopsis suppressing resistance to Peronospora parasitica specified by several different RPP genes
33. The Arabidopsis downy mildew resistance gene RPP5 shares similarity to the Toll and interleukin-1 receptors with N and L6
34. Unravelling R gene-mediated disease resistance pathways in Arabidopsis
35. Novel disease resistance specificities result from sequence exchange between tandemly repeated genes at the Cf-4/9 locus of tomato
36. Characterization of the tomato Cf-4 gene for resistance to Cladosporium fulvum identifies sequences that determine recognitional specificity in Cf-4 and Cf-9
37. Map positions of three loci in Arabidopsis thaliana associated with isolate-specific recognition of Peronospora parasitica (downy mildew)
38. The NB-ARC domain: A novel signalling motif shared by plant resistance gene products and regulators of cell death in animals
39. Plant disease resistance proteins and the gene-for-gene concept
40. Arabidopsis RelA/SpoT homologs implicate (p)ppGpp in plant signaling
41. Homologues of a single resistance-gene cluster in potato confer resistance to distinct pathogens: A virus and a nematode
42. A mutation within the leucine-rich repeat domain of the Arabidopsis disease resistance gene RPS5 partially suppresses multiple bacterial and downy mildew resistance genes
43. Identification of three putative signal transduction genes involved in R gene-specified disease resistance in Arabidopsis
44. Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene
45. PAD4 functions upstream from salicylic acid to control defense responses in Arabidopsis