The Role of Leucine-Rich Repeat Proteins in Plant Defences

Advances in Botanical Research

Volumn 24, Issue C, 1997, Pages 89-167

  Jones, D A ^a   Jones, J D G ^a  

^a SAINSBURY LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77956742948     PISSN: 00652296     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2296(08)60072-5     Document Type: Article

References (181)

1. Aatsinki J.J., Pietilä E.M., Lakkakorpi J.T., and Rajaniemi H.J. Expression of the LH/CG receptor gene in rat ovarian tissue is regulated by an extensive alternative splicing of the primary transcript. Molecular and Cellular Endocrinology 84 (1992) 127-135
2. Abu-Goukh A.A., and Labavitch J.M. The in vivo role of "Bartlett" pear fruit polygalacturonase inhibitors. Physiological Plant Pathology 23 (1983) 123-135
3. Abu-Goukh A.A., Greve L.C., and Labavitch J.M. Purification and partial characterization of "Bartlett" pear fruit polygalacturonase inhibitors. Physiological Plant Pathology 23 (1983) 111-122
4. Alexander D., Goodman R.M., Gut-Rella M., Glascock C., Weymann K., Friedrich L., Maddox D., Ahl-Goy P., Luntz T., Ward E., and Ryals J. Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein la. Proceedings of the National Academy of Sciences, USA 90 (1993) 7327-7331
5. Ashfield T., Hammond-Kosack K.E., Harrison K., and Jones J.D.G. Cf gene-dependent induction of a β-1,3-glucanase promoter in tomato plants infected with Cladosporium fulvum. Molecular Plant-Microbe Interactions 7 (1994) 645-657
6. Belvin M.P., Jion Y., and Anderson K.V. Cactus protein degradation mediates Drosophilia dorsal-ventral signaling. Genes and Development 9 (1995) 783-793
7. Bent A.F., Kunkel B.N., Dahlbeck D., Brown K.I., Schmidt R., Giraudat J., Leung J., and Staskawicz B.J. RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of disease resistance genes. Science 265 (1994) 1856-1860
8. Bergmann C.W., Ito Y., Singer D., Albersheim P., Darvill A.G., Benhamou N., Nuss L., Salvi G., Cervone F., and De Lorenzo G. Polygalac-turonase-inhibiting protein accumulates in Phaseolus vulgaris L. in response to wounding, elicitors and fungal infection. The Plant Journal 5 (1994) 625-634
9. Boguski M.S., and McCormick F. Proteins regulating Ras and its relatives. Nature 366 (1993) 643-654
10. Bol J.F., Linthorst H.J.M., and Cornelissen B.J.C. Plant pathogenesis-related proteins induced by virus infection. Annual Review of Phytopathology 28 (1990) 113-138
11. Bonas U., Stall R.E., and Staskawicz B. Genetic and structural characterization of the avirulence gene avrBs3 from Xanthomonas campestris pv. vesicatoria. Molecular and General Genetics 218 (1989) 127-136
12. Bonas U., Conrads-Strauch J., and Balbo I. Resistance in tomato to Xanthomonas campestris pv. vesicatoria is determined by alleles of the pepper-specific avirulence gene avrBs3. Molecular and General Genetics 238 (1993) 261-269
13. Bowles D.J. Defense-related proteins in higher plants. Annual Review of Biochemistry 59 (1990) 873-907
14. Brown I., Mansfield J., Irlam I., Conrads-Strauch J., and Bonas U. Ultrastructure of interactions between Xanthomonas campestris pv. vesicatoria and pepper, including immunocytochemical localization of extracellular polysaccharides and the avrBs3 protein. Molecular Plant-Microbe Interactions 6 (1993) 376-386
15. Calder V.L., and Palukaitis P. Nucleotide sequence analysis of the movement genes of resistance breaking strains of tomato mosaic virus. Journal of General Virology 73 (1992) 165-168
16. Cao Z., Henzel W.J., and Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science 271 (1996) 1128-1131
17. Century K.S., Holub E.B., and Staskawicz B.J. NDR1, a locus of Arabidopsis thaliana that is required for disease resistance to both a bacterial and a fungal pathogen. Proceedings of the National Academy of Sciences USA 92 (1995) 6597-6601
18. Cervone F., De Hahn M.G., Lorenzo G., Darvill A., and Albersheim P. Host-pathogen interactions. XXXIII. A plant protein converts a fungal pathogenesis factor into an elicitor of plant defense responses. Plant Physiology 90 (1989) 542-548
19. Chang C., Schaller G.E., Patterson S.E., Kwok S.F., Meyerowitz E.M., and Bleecker A.B. The TMK1 gene from Arabidopsis codes for a protein with structural and biochemical characteristics of a receptor protein kinase. The Plant Cell 4 (1992) 1263-1271
20. Chasan R. Disease resistance: beyond the R genes. The Plant Cell 6 (1994) 461-463
21. Clark S.E., Running M.P., and Meyerowitz E.M. CLAVATA1, a regulator of meristem and flower development in Arabidopsis. Development 119 (1993) 397-418
22. Culver J.N., and Dawson W.O. Tobacco mosaic virus coat protein: an elicitor of the hypersensitive reaction but not required for the development of mosaic symptoms in Nicotiana sylvestris. Virology 173 (1989) 755-758
23. Cutler M.L., Bassin R.H., Zanoni L., and Talbot N. Isolation of rsp-1, a novel cDNA capable of suppressing v-ras transformation. Molecular and Cellular Biology 12 (1992) 3750-3756
24. Dangl J.L. The major histocompatibility complex à la carte: are there analogies to plant disease resistance genes on the menu. The Plant Journal 2 (1992) 3-11
25. Dangl J.L., Ritter C., Gibbon M.J., Mur L.A.J., Woods J.R., Goss S., Mansfield J.W., Taylor J.D., and Vivian A. Functional homologs of the Arabidopsis RPM1 disease resistance gene in bean and pea. The Plant Cell 4 (1992) 1359-1369
26. De Feyter R., Yang Y., and Gabriel D.W. Gene-for-genes interactions between cotton R genes and Xanthomonas campestris pv. malvacearum avr genes. Molecular Plant-Microbe Interactions 6 (1993) 225-237
27. De Lorenzo G., Ito Y., D'Ovidio R., Cervone F., Albersheim P., and Darvill A.G. Host-pathogen interactions. XXXVII. Abilities of the polygalacturonase-inhibiting proteins of races of Colletotrichum lin-demuthianum. Physiological and Molecular Plant Pathology 36 (1990) 421-435
28. Dinesh-Kumar S.P., Whitham S., Choi D., Hehl R., Corr C., and Baker B. Transposon tagging of tobacco mosaic virus resistance gene N: its possible role in the TMV- N-mediated signal transduction pathway. Proceedings of the National Academy of Sciences, USA 92 (1995) 4175-4180
29. Dixon M.S., Jones D.A., Keddie J.S., Thomas C.M., Harrison K., and Jones J.D.G. The tomato Cf-2 disease resistance locus comprises two functional genes encoding leucine-rich repeat proteins. Cell 84 (1996) 159-451
30. Eldon E., D'Kooyer S., Evelyn D., Duman M., Lawinger P., Botas J., and Bellen H. The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll. Development 120 (1994) 885-899
31. Ellis J.G., Lawrence G.J., Anderson P.A., and Finnegan E.J. Contrasting complexity of two rust resistance loci in flax. Proceedings of the National Academy of Sciences, USA 92 (1995) 4185-4188
32. Favaron F., D'Ovidio R., Porceddu E., and Alghisi P. Purification and molecular characterization of a soybean polygalacturonase-inhibiting protein. Planta 195 (1994) 80-87
33. Fenselau S., Balbo I., and Bonas U. Determinants of pathogenicity in Xanthomonas campestris pv. vesicatoria are related to proteins involved in secretion in bacterial pathogens of animals. Molecular Plant-Microbe Interactions 5 (1992) 390-396
34. Frediani M., Cremonini R., Salvi G., Caprari C., Desiderio A., D'Ovidio R., Cervone F., and De Lorenzo G. Cytological localization of the PGIP genes in the embryo suspensor cells of Phaseolus vulgaris L. Theoretical and Applied Genetics 87 (1993) 369-373
35. 12-specified race-specific resistance to powdery mildew in barley. The Plant Cell 6 (1994) 983-994
36. Fujimura Y., Titani K., Usami Y., Suzuki M., Oyama R., Matsui T., Fukui H., Sugimoto M., and Ruggeri Z.M. Isolation and characterization of two structurally and functionally distinct forms of botrocetin, the platelet coagglutinin isolated from the venom of Bothrops jararaca. Biochemistry 30 (1991) 1957-1964
37. Gabriel D.W., and Rolfe B.G. Working models of specific recognition in plant-microbe interactions. Annual Review of Phytopathology 28 (1990) 365-391
38. Galindo R.L., Edwards D.N., Gillespie S.K.H., and Wasserman S.A. Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos. Development 121 (1995) 2209-2218
39. Geisler R., Bergmann A., Hiromi Y., and Nüsslein-Volhard C. cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IkB gene family of vertebrates. Cell 71 (1992) 613-621
40. Grant M.R., Godiard L., Straube E., Ashfield T., Lewald J., Sattler A., Innes R.W., and Dangl J.L. Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance. Science 269 (1995) 843-846
41. Gross B., Misrahi M., Sar S., and Milgrom E. Composite structure of the human thyrotropin receptor gene. Biochemical and Biophysical Research Communications 177 (1991) 679-687
42. Goulden M.G., Santa Köhm B.A., Cruz S., Kavanagh T.A., and Baulcombe D.C. A feature of the coat protein of potato virus X affects both induced virus resistance in potato and viral fitness. Virology 197 (1993) 293-302
43. Guida S., Heguy A., and Melli M. The chicken IL-1 receptor: differential evolution of the cytoplasmic and extracellular domains. Gene 111 (1992) 239-243
44. Halfon M.S., Hashimoto C., and Keshishian H. The Drosophila Toll gene functions zygotically and is necessary for proper motorneuron and muscle development. Developmental Biology 169 (1995) 151-167
45. Hammond-Kosack K.E., and Jones J.D.G. Incomplete dominance of tomato Cf genes for resistance to Cladosporium fulvum. Molecular Plant-Microbe Interactions 7 (1994) 58-70
46. Hammond-Kosack K.E., Jones D.A., and Jones J.D.G. Identification of two genes required in tomato for full Cf-9-dependent resistance to Cladosporium fulvum. The Plant Cell 6 (1994) 361-374
47. Hammond-Kosack K.E., Silverman P., Raskin I., and Jones J.D.G. Race-specific elicitors of Cladosporium fulvum induce changes in cell morphology and the synthesis of ethylene and salicylic acid in tomato plants carrying the corresponding Cf-disease resistance gene. Plant Physiology 110 (1996) 1381-1394
48. Hashimoto C., Hudson K.L., and Anderson K.V. The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein. Cell 52 (1988) 269-279
49. Heckert L.L., Daley I.J., and Griswold M.D. Structural organization of the follicle-stimulating hormone receptor gene. Molecular Endocrinology 6 (1992) 70-80
50. Heldin C.-H. Dimerization of cell surface receptors in signal transduction. Cell 80 (1995) 213-223
51. Herbers K., Conrads-Strauch J., and Bonas U. Race-specificity of plant resistance to bacterial spot disease determined by repetitive motifs in a bacterial avirulence protein. Nature 356 (1992) 172-174
52. Hisamoto N., Frederick D.L., Sugimoto K., Tatchell K., and Matsumoto K. The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae. Molecular and Cellular Biology 15 (1995) 3767-3776
53. Hopkins C.M., White F.F., Choi S.-H., Guo A., and Leach J.E. Identification of a family of avirulence genes from Xanthomonas oryzae pv.oryzae. Molecular Plant-Microbe Interactions 5 (1992) 451-459
54. Hopp T.P. Evidence from sequence information that the interleukin-1 receptor is a transmembrane GTPase. Protein Science 4 (1995) 1851-1859
55. Horn M.A., Heinstein P.F., and Low P.S. Receptor-mediated endocytosis in plant cells. The Plant Cell 1 (1989) 1003-1009
56. Hunter T. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80 (1995) 225-236
57. Huynh T.V., Dahlbeck D., and Staskawicz B.J. Bacterial blight of soybean: regulation of a pathogen gene determining host cultivar specificity. Science 245 (1989) 1374-1377
58. Innes R.W., Bent A.F., Kunkel B.M., Bisgrove S.R., and Staskawicz B.J. Molecular analysis of avirulence gene avrRpt2 and identification of a putative regulatory sequence common to all known Pseudomonas syringae avirulence genes. Journal of Bacteriology 175 (1993) 4859-4869
59. Ip Y.T., Reach M., Engstrom Y., Kadalayil L., Cai H., González-Crespo S., Tatei K., and Levine M. Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell 75 (1993) 753-763
60. Ji L.-H., and Langridge P. An early meiosis cDNA clone from wheat. Molecular and General Genetics 243 (1994) 17-23
61. Johnston D.J., Ramanathan V., and Williamson B. A protein from immature raspberry fruits which inhibits endopolygalacturonases from Botrytis cinerea and other micro-organisms. Journal of Experimental Botany 44 (1993) 971-976
62. Johnston D.J., Williamson B., and McMillan G.P. The interaction in planta of polygalacturonases from Botrytis cinerea with a cell wall-bound polygalac-turonase-inhibiting protein (PGIP) in raspberry fruits. Journal of Experimental Botany 45 (1994) 1837-1843
63. Jones D.A., Thomas C.M., Hammond-Kosack K.E., Balint-Kurti P.J., and Jones J.D.G. Isolation of the tomato Cf-9 gene for resistance to Cladosporium fulvum by transposon tagging. Science 266 (1994) 789-793
64. Joosten M.H., Cozijnsen A.J.T.J., and De Wit P.J.G.M. Host resistance to a fungal tomato pathogen lost by a single base-pair change in an avirulence gene. Nature 367 (1994) 384-386
65. Kajava A.V., Vassart G., and Wodak S. Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. Structure 3 (1995) 867-877
66. Kataoka T., Broek D., and Wigler M. DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase. Cell 47 (1985) 493-505
67. Kearney B., and Staskawicz B.J. Widespread distribution and fitness contribution of Xanthomonas campestris avirulence gene avrBs2. Nature 346 (1990) 385-386
68. Keen N.T. Gene-for-gene complementarity in plant-pathogen interactions. Annual Review of Genetics 24 (1992) 447-463
69. Keith F.J., and Gay N.J. The Drosophila membrane receptor Toll can function to promote cellular adhesion. The EMBO Journal 9 (1990) 4299-4306
70. Kidd S. Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins. Cell 71 (1992) 623-635
71. Kieliszewski M.J., and Lamport D.T.A. Extensin: repetitive motifs, functional sites, post-translational codes, and phylogeny. The Plant Journal 5 (1994) 157-172
72. Knoop V., Staskawicz B., and Bonas U. Expression of the avirulence gene avrBs3 from Xanthomonas campestris pv. vesicatoria is not under the control of hrp genes and is independent of plant factors. Journal of Bacteriology 173 (1991) 7142-7150
73. Kobe B., and Deisenhofer J. Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 366 (1993) 751-756
74. Kobe B., and Deisenhofer J. The leucine-rich repeat: a versatile binding motif. Trends in Biochemical Sciences 19 (1994) 415-421
75. Kobe B., and Deisenhofer J. A structural basis of the interactions between leucine-rich repeats and protein ligands. Nature 374 (1995) 183-186
76. Kobe B., and Deisenhofer J. Proteins with leucine-rich repeats. Current Opinion in Structural Biology 5 (1995) 409-416
77. Koo Y.B., Ji I., Slaughter R.G., and Ji T.H. Structure of the luteinizing hormone receptor gene and multiple exons of the coding sequence. Endocrinology 128 (1991) 2297-2308
78. Kooman-Gersmann M., Honee G., Bonnema G., and De Wit P.J.G.M. A high affinity binding site for the AVR9 peptide elicitor of Cladosporium fulvum is present on plasma membranes of tomato and other solanaceous plants. The Plant Cell 8 (1996) 929-938
79. van der Kooter J.M., Spek H.J., Wagter R., d'Oliveira C.E., van der Hoeven F., Johnson P.J., and Borst P. The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. brucei. Cell 51 (1987) 261-272
80. Lafitte C., Barthe J.P., Montillet J.L., and Touzé A. Glycoprotein inhibitors of Colletotrichum lindemuthianum endoploygalacturonase in near isogenic lines of Phaseolus vulgaris resistant and susceptible to anthracnose. Physiological Plant Pathology 25 (1984) 39-53
81. Lawrence G.J., Finnegan E.J., Ayliffe M.A., and Ellis J.G. The L6 gene for flax rust resistance is related to the Arabidopsis bacterial resistance gene RPS2 and the tobacco viral resistance gene N. The Plant Cell 7 (1995) 1195-1206
82. Leevers S.J., Paterson H.F., and Marshall C.J. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369 (1994) 411-414
83. Letsou A., Alexander S., Orth K., and Wasserman S.A. Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity. Proceedings of the National Academy of Sciences, USA 88 (1991) 810-814
84. Linthorst H.J.M. Pathogenesis-related proteins of plants. Critical Reviews in Plant Sciences 10 (1991) 123-150
85. Loh Y.-T., and Martin G.B. The disease-resistance gene Pto and the fenthion-sensitivity gene Fen encode closely related functional protein kinases. Proceedings of the National Academy of Sciences USA 92 (1995) 4181-4184
86. Loh Y.-T., and Martin G.B. The Pto bacterial resistance gene and the Fen insecticide sensitivity gene encode functional protein kinases with serine/threonine specificity. Plant Physiology 108 (1995) 1735-1739
87. Lohman K.L., Langer P.J., and Mc Mahon-Pratt D. Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis. Proceedings of the National Academy of Sciences USA 87 (1990) 8393-8397
88. Lopez J.A. The platelet glycoprotein Ib-IX complex. Blood Coagulation and Fibrinolysis 5 (1994) 97-119
89. Lorang J.M., Shen H., Kobayashi D., Cooksey D., and Keen N.T. avrA avrE in Psedomonas syringae pv. tomato PT23 play a role in virulence on tomato plants. Molecular Plant-Microbe Interactions 7 (1994) 508-515
90. Lord K.A., Hoffman-Liebermann B., and Liebermann D.A. Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6. Oncogene 5 (1990) 1095-1097
91. MacKelvie S.H., Andrews P.D., and Stark M.J.R. The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase. Molecular and Cellular Biology 15 (1995) 3777-3785
92. Marais R., Light Y., Paterson H.F., and Marshall C.J. Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. The EMBO Journal 14 (1995) 3136-3145
93. Martin G.B., Brommonschenkel S.H., Chunwongse J., Frary A., Ganal M.W., Spivy R., Wu T., Earle E.D., and Tanksley S.D. Map-based cloning of a protein kinase gene conferring disease resistance in tomato. Science 262 (1993) 1432-1436
94. May M.J., Hammond-Kosack K.E., and Jones J.D.G. Involvement of reactive oxygen species, glutathione metabolism and lipid peroxidation in the Cf-gene-dependent defense response of tomato cotyledons induced by race-specific elicitors of Cladosporium fulvum. Plant Physiology 110 (1996) 1367-1379
95. Meshi T., Motoyoshi F., Adachi A., Watanabe Y., Takamatsu N., and Okada Y. Two concomitant base substitutions in the putative replicase genes of tobacco mosaic virus confer the ability to overcome the effects of a tomato resistance gene, Tm-1. The EMBO Journal 7 (1988) 1575-1581
96. Meshi T., Motoyoshi F., Maeda T., Yoshiwoka S., Watanabe H., and Okada Y. Mutations in the tobacco mosaic virus 30-kD protein gene overcome Tm-2 resistance in tomato. The Plant Cell 1 (1989) 515-522
97. Mindrinos M., Katagiri F., Yu G.-L., and Ausubel F.M. The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell 78 (1994) 1089-1099
98. Miyake K., Yamashita Y., Ogata M., Sudo T., and Kimoto M. RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. The Journal of Immunology 154 (1995) 3333-3340
99. Mowatt M.R., Luján H.D., Cotten D.B., Bowers B., Yee J., Nash T.E., and Stibbs H.H. Developmentall regulated expression of a Giardia lamblia cyst wall protein gene. Molecular Microbiology 15 (1995) 955-963
100. Mu J.-H., Lee H.-S., and Kao T.-H. Characterization of a pollen-expressed receptor-like kinase gene of Petunia inflata and the activity of its encoded kinase. The Plant Cell 6 (1994) 709-721
101. Murray P.J., and Spithill T.W. Variants of a Leishmania surface antigen derived from a multigene family. The Journal of Biological Chemistry 266 (1991) 24477-24484
102. Nothacker H.-P., and Grimmelikhuijzen C.J.P. Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals. Biochemical and Biophysical Research Communications 197 (1993) 1062-1069
103. Nuss L., Mahé A., Clark A.J., Grisvard J., Dron M., Cervone F., and De Lorenzo G. Differential accumulation of PGIP (polygalacturonase-inhibiting protein) mRNA in two near-isogenic lines of Phaseolus vulgaris L. upon infection with Colletotrichum lindemuthianum. Physiological and Molecular Plant Pathology 48 (1996) 83-89
104. + essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1. Cell 64 (1991) 149-157
105. 34 is a member of the leucine-rich-repeat-protein superfamily. Biochemical Journal 294 (1993) 465-472
106. Orozco-Cardenas M., McGurl B., and Ryan C.A. Expression of an antisense prosystemin gene in tomato plants reduces resistance toward Manduca sexta larvae. Proceedings of the National Academy of Sciences USA 90 (1993) 8273-8276
107. Padgett H.S., and Beachy R.N. Analysis of a tobacco mosaic virus strain capable of overcoming N gene-mediated resistance. The Plant Cell 5 (1993) 577-586
108. Pang Q., Hays J.B., and Rajagopal I. A plant cDNA that partially complements Escherichia coli recA mutations predicts a polypeptide not strongly homologous to recA proteins. Proceedings of the National Academy of Sciences USA 89 (1992) 8073-8077
109. Pearce G., Strydom D., Johnson S., and Ryan C.A. A polypeptide from tomato leaves induces wound-inducible proteinase inhibitor proteins. Science 253 (1991) 895-897
110. Petersen U.-M., Björklund G., Ip Y.T., and Engström Y. The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila Cecropin gene expression. The EMBO Journal 14 (1995) 3146-3158
111. Pryor T., and Ellis J. The genetic complexity of fungal resistance genes in plants. Advances in Plant Pathology 10 (1993) 281-305
112. Reddy J.T., Dudareva N., Evrard J.-L., Kräuter R., Steinmitz A., and Pillay D.T.N. A pollen-specific gene from sunflower encodes a member of the leucine-rich repeat protein superfamily. Plant Science 111 (1995) 81-93
113. Reuber T.L., and Ausubel F.M. Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 RPM1 disease resistance genes. The Plant Cell 8 (1996) 241-249
114. Revelard P., Lips S., and Pays E. A gene from the VSG expression site of Trypanosoma brucei encodes a protein with both leucine-rich repeats and a putative zinc finger. Nucleic Acids Research 18 (1990) 7299-7303
115. Ritter C., and Dangl J.L. The avrRpml gene of Pseudomonas syringae pv. maculicola is required for virulence on Arabidopsis. Molecular Plant-Microbe Interactions 8 (1995) 444-453
116. Ritter C., and Dangl J.L. Interference between two specific pathogen recognition events mediated by distinct plant disease resistance genes. The Plant CellS 8 (1996) 251-257
117. Roberts P.A. Current status of the availability, development, and use of host plant disease resistance to nematodes. Journal of Nematology 24 (1992) 213-227
118. Rohe M., Gierlich A., Hermann H., Hahn M., Schmidt B., Rosahl S., and Knogge W. The race-specific elicitor, NIP1, from the barley pathogen, Rhynchosporim secalis determines avirulence on host plants of the Rrsl resistance genotype. The EMBO Journal 14 (1995) 4168-4177
119. Rommens C.M.T., Salmeron J.M., Baulcombe D.C., and Staskawicz B.J. Use of a gene expression system based on potato virus X to rapidly identify and characterize a tomato Pto homolog that controls fenthion sensitivity. The Plant Cell 7 (1995) 249-257
120. Ronald P.C., Albano B., Tabien R., Abenes L., Wu K.-S., McCouch S., and Tanksley S.D. Genetic and physical analysis of the rice bacterial blight disease resistance locus, Xa-21. Molecular and General Genetics 236 (1992) 113-120
121. Rosqvist R., Magnusson K.-E., and Wolf-Watz H. Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells. The EMBO Journal 13 (1994) 964-972
122. Rosqvist R., Håkansson S., Forsberg A., and Wolf-Watz H. Functional conservation of the secretion and translocation machinery for virulence proteins of yersiniae, salmonellae and shigellae. The EMBO Journal 14 (1995) 4187-4195
123. Ross D.T., Raibaud A., Florent I.C., Sather S., Gross M.K., Storm D.R., and Eisen H. The trypanosome VSG expression site encodes adenylate cyclase and a leucine-rich putative regulatory gene. The EMBO Journal 10 (1991) 2047-2053
124. Rubenstein A.L., Broadwater A.H., Lowrey K.B., and Bedinger P.A. Pexl a pollen-specific gene with an extensin-like domain. Proceedings of the National Academy of Sciences USA 92 (1995) 3086-3090
125. Rushlow C., and Warrior R. The rel family of proteins. Bio Essays 14 (1992) 89-95
126. Ryals J., Uknes S., and Ward E. Systemic acquired resistance. Plant Physiology 104 (1994) 1109-1112
127. Salmeron J.M., and Staskawicz B.J. Molecular characterization and hrp dependence of the avirulence gene avrPto from Pseudomonas syringae pv. tomato. Molecular and General Genetics 239 (1993) 6-16
128. Salmeron J.M., Barker S.J., Carland F.M., Mehta A.Y., and Staskawicz B.J. Tomato mutants altered in bacterial disease resistance provide evidence for a new locus controlling pathogen recognition. The Plant Cell 6 (1994) 511-520
129. Salmeron J.M., Oldroyd G.E.D., Rommens C.M.T., Scofield S.R., Kim H.-S., Lavelle D.T., Dahlbeck D., and Staskawicz B.J. Tomato Prf is a member of the leucine-rich repeat class of plant disease resistance genes and lies embedded within the Pto kinase gene cluster. Cell 86 (1996) 123-133
130. Salvi G., Giarrizzo F., De Lorenzo G., and Cervone F. A polygalacturonase-inhibiting protein in the flowers of Phaseolus vulgaris L. Journal of Plant Physiology 136 (1990) 513-518
131. Schneider D.S., Jin Y., Morisato D., and Anderson K.V. A processed form of the Spatzle protein defines dorsal-ventral polarity in the Drosophila embryo. Development 120 (1994) 1243-1250
132. Segal A.W., and Abo A. The biochemical basis of the NADPH oxidase of phagocytes. Trends in Biochemical Sciences 18 (1993) 43-47
133. Shapiro R., Riordan J.F., and Vallee B.L. LRRning the Rite of springs. Structural Biology 2 (1995) 350-354
134. Sharrock K.R., and Labavitch J.M. Polygalacturonase inhibitors of Bartlett pear fruits: differential effects on Botrytis cinerea polygalacturonase isozymes, and influence on products of fungal hydrolysis of pear cell walls and on ethylene production in cell culture. Physiological and Molecular Plant Pathology 45 (1994) 305-319
135. Shelton C.A., and Wasserman S.A. Pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo. Cell 72 (1993) 515-525
136. Shen H., and Keen N.T. Characterization of the promoter of avirulence gene D from Pseudomonas syringae pv. tomato. Journal of Bacteriology 175 (1993) 5916-5924
137. Showalter A.M. Structure and function of cell wall proteins. The Plant Cell 5 (1993) 9-23
138. Siebenlist U., Franzoso G., and Brown K. Structure, regulation and function of NFkB. Annual Review of Cell Biology 10 (1994) 405-455
139. Simpson C.G., MacRae E., and Gardner R.C. Cloning of a polygalacturonase-inhibiting protein from kiwifruit (Actinidia deliciosa) [Genbank Z49063] (PGR95-036). Plant Physiology 108 (1995) 1748
140. Sims J.E., March C.J., Cosman D., Widmer M.B., MacDonald H.R., McMahan C.J., Grubin C.E., Wignall J.M., Jackson J.L., Call S.M., Friend D., Alpert A.R., Gillis S., Urdal D.L., and Dower S.K. cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 241 (1988) 585-589
141. Sims J.E., Acres R.B., Grubin C.E., McMahan C.J., Wignall J.M., March C.J., and Dower S.K. Cloning the interleukin 1 receptor from human T cells. Proceedings of the National Academy of Sciences USA 86 (1989) 8946-8950
142. Smiley B.L., Stadnyk A.W., Myler P.J., and Stuart K. The trypanosome leucine repeat gene in the variant surface glycoprotein expression site encodes a putative metal-binding domain and a region resembling protein-binding domains of yeast, Drosophila and mammalian proteins. Molecular and Cellular Biology 10 (1990) 6436-6444
143. Smith M.J., Mazzola M.P., Sims J.J., Midland S.L., Keen N.T., Burton V., and Stayton M.M. The syringolides: bacterial C-glycosyl lipids that trigger plant disease resistance. Tetrahedron Letters 34 (1993) 223-226
144. Song W.-Y., Wang G.-L., Chen L.-L., Kim H.-S., Pi L.-Y., Holsten T., Gardner J., Wang B., Zhai W.-X., Zhu L.-H., Fauquet C., and Ronald P. A receptor kinase-like protein encoded by the rice disease resistance gene, Xa-21. Science 270 (1995) 1804-1806
145. Steimle V., Otten L.A., Zufferey M., and Mach B. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75 (1993) 135-146
146. Steinmayr M., Motte P., Sommer H., Saedler H., and Schwarz-Sommer Z. FIL2, an extracellular leucine-rich repeat protein, is specifically expressed in Antirrhinum flowers. The Plant Journal 5 (1994) 459-467
147. Steward R. Dorsal an embryonic polarity gene in Drosophila is homologous to the vertebrate proto-oncogene, c-rel. Science 238 (1987) 692-694
148. Stokoe D., MacDonald S.G., Cadwallader K., Symons M., and Hancock J.F. Activation of Raf as a result of recruitment to the plasma membrane. Science 264 (1994) 1463-1467
149. Stone J.M., Collinge M.A., Smith R.D., Horn M.A., and Walker J.C. Interaction of a protein phosphatase with an Arabidopsis serine-threonine receptor kinase. Science 266 (1994) 793-795
150. Stotz H.U., Powell A.L.T., Damon S.E., Greve L.C., Bennet A.B., and Labavitch J.M. Molecular characterization of a polygalacturonase inhibitor from Pyrus communis L. cv Bartlett. Plant Physiology 102 (1993) 133-138
151. Stotz H.U., Contos J.J.A., Powell A.L.T., Bennet A.B., and Labavitch J.M. Structure and expression of an inhibitor of fungal polygalacturonases from tomato. Plant Molecular Biology 25 (1994) 607-617
152. Stynes B.A., and Bird A.F. Development of galls induced in Lolium rigidum by Anguina agrostis. Phytopathology 72 (1982) 336-346
153. Suzuki N., Choe H.-R., Nishida Y., Yamawaki-Kataoka Y., Ohnishi S., Tamaoki T., and Kataoka T. Leucine-rich repeats and carboxyl terminus are required for interaction of yeast adenylate cyclase with RAS proteins. Proceedings of the National Academy of Sciences USA 87 (1990) 8711-8715
154. Swruap S., Yang Y., Kingsley M.T., and An Gabriel D.W. Xanthomonas citri pathogenicity gene, pthA pleiotropically encodes gratuitous avirulence on non-hosts. Molecular Plant-Microbe Interactions 5 (1992) 204-213
155. Tamaki S., Dahlbeck D., Staskawicz B., and Keen N.T. Characterization and expression of two avirulence genes cloned from Pseudomonas syringae pv.glycinea. Journal of Bacteriology 170 (1988) 4846-4854
156. Tenhaken R., Levine A., Brisson L.F., Dixon R.A., and Lamb C. Function of the oxidative burst in hypersensitive disease resistance. Proceedings of the National Academy of Sciences USA 92 (1995) 4158-4163
157. Torii K.U., Mitsukawa N., Oosumi T., Matsuura Y., Yokoyama R., Whittier R.F., and Komeda Y. The Arabidopsis ERECTA gene encodes a putative receptor protein kinase with extracellular leucine-rich repeats. The Plant Cell 8 (1996) 735-746
158. Tornero P., Mayda E., Gomez M.D., Canas L., Conejero V., and Vera P. Characterization of LRP, a leucine-rich repeat (LRR) protein from tomato plants that is processed during pathogenesis. The Plant Journal 10 (1996) 315-330
159. Toubart P., Desiderio A., Salvi G., Cervone F., Daroda L., and De Lorenzo G. Cloning and characterization of the gene encoding the endopolygalac-turonase-inhibiting protein (PGIP) of Phaseolus vulgaris L. The Plant Journal 2 (1992) 367-373
160. Traut T.W. The functions and consensus motifs of nine types of peptide segments that form different types of nucleotide-binding sites. European Journal of Biochemistry 222 (1994) 9-19
161. Tsai-Morris C.H., Buczko E., Wang W., Xie X.-Z., and Dufau M.L. Structural organization of the rat luteinizing hormone (LH) receptor gene. Journal of Biological Chemistry 266 (1991) 11355-11359
162. Usami Y., Fujimura Y., Suzuki M., Ozeki Y., Nishio K., Fukui H., and Titani K. Primary structure of two-chain botrocetin, a von Willebrand factor modulator from the venom of Bothrops jararaca. Proceedings of the National Academy of Sciences USA 90 (1993) 928-932
163. Valon C., Smalle J., Goodman H.M., and Giraudat J. Characterization of an Arabidopsis thaliana gene (TMKL1) encoding a putative transmembrane protein with an unusual kinase-like domain. Plant Molecular Biology 23 (1993) 415-421
164. van den Ackerveken G.F., van Kan J.A.L., and de Wit P.G.J.M. Molecular analysis of the avirulence gene avr9 of the fungal tomato pathogen Cladosporium fulvum fully supports the gene-for-gene hypothesis. The Plant Journal 2 (1992) 359-366
165. Van Gijsegem F., Genin S., and Boucher C. Conservation of secretion pathways for pathogenicity determinants of plant and animal bacteria. Trends in Microbiology 1 (1993) 175-180
166. 1H NMR assignments, secondary structure and global fold of the face-specific elicitor AVR9 of the tomato pathogen Cladosporium fulvum. European Journal of Biochemistry (1996) (in press)
167. Walker J.C. Receptor-like protein kinase genes of Arabidopsis thaliana. The Plant Journal 3 (1993) 451-456
168. Ward E.R., Uknes S.J., Williams S.C., Dincher S.S., Wiederhold D.L., Alexander D.C., Ahl-Goy P., Metraux J.-P., and Ryals J.A. Coordinate gene activity in response to agents that induce systemic acquired resistance. The Plant Cell 3 (1991) 1085-1094
169. 2 resistance gene in the tomato. Journal of Virology 67 (1993) 6432-6438
170. Weiss A., and Littman D.R. Signal transduction by lymphocyte antigen receptors. Cell 76 (1994) 263-274
171. Whitham S., Dinesh-Kumar S.P., Choi D., Hehl R., Corr C., and Baker B. The product of the tobacco mosaic virus resistance gene N: similarity to Toll and the interleukin-1 receptor. Cell 78 (1994) 1101-1115
172. Willis D.K., Rich J.J., and Hrabak E.M. Hrp genes of phytopathogenic bacteria. Molecular Plant-Microbe Interactions 4 (1991) 132-138
173. Yanagisawa K., Takagi T., Tsukamoto T., Tetsuka T., and Tominaga S. Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin-1 receptor type 1. FEBS Letters 318 (1993) 83-87
174. Yang Y., and Gabriel D.W. Xanthomonas avirulence/pathogenicity gene family encodes functional plant nuclear targeting signals. Molecular Plant-Microbe Interactions 8 (1995) 627-631
175. Yang Y., and Gabriel D.W. Intragenic recombination of a single plant pathogen gene provides a mechanism for the evolution of new host specificities. Journal of Bacteriology 177 (1995) 4963-4968
176. De Yang Y., Feyter R.E., and Gabriel D.W. Host-specific symptoms and increased release of Xanthomonas citri X. campestris pv. malvacearum from leaves are determined by the 102-bp tandem repeats of pthA avrb6, respectively. Molecular Plant-Microbe Interactions 7 (1994) 345-355
177. Yang Y., Yuan Q., and Gabriel D.W. Watersoaking function(s) of XcmH1005 are redundantly encoded by members of the avr/pth gene family. Molecular Plant-Microbe Interactions 9 (1996) 105-113
178. Yao C., Conway W.S., and Sams C.E. Purification and characterization of a polygalacturonase-inhibiting protein from apple fruit. Phytopathology 85 (1995) 1373-1377
179. Young S.A., White F.F., Hopkins C.M., and Leach J.E. AVRXa10 protein is in the cytoplasm of Xanthomonas oryzae pv.oryzae. Molecular Plant-Microbe Interactions 7 (1994) 799-804
180. Zhang R., Cai H.Q., Fatima M., Buczko E., and Dufau M.L. Functional glycosylation sites of the rat luteinizing-hormone receptor required for ligand binding. Journal of Biological Chemistry 270 (1995) 21722-21728
181. Zhou J., Rumeau D., and Showalter A.M. Isolation and characterization of two wound-regulated tomato extensin genes. Plant Molecular Biology 20 (1992) 5-17