Sympathetic neural control of skeletal muscle blood flow and oxygenation

Danish Medical Bulletin

Volumn 49, Issue 2, 2002, Pages 109-129

  Hansen, Jim ^a  

^a NONE   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC ACTIVITY; ADRENERGIC SYSTEM; ARTICLE; HUMAN; MUSCLE BLOOD FLOW; MUSCLE CONTRACTION; MUSCLE EXERCISE; MUSCLE TISSUE; NONHUMAN; TISSUE OXYGENATION; VASOCONSTRICTION; VASODILATATION; ANIMAL; BLOOD; EXERCISE; INNERVATION; MICROCIRCULATION; PHYSIOLOGY; RAT; REVIEW; SKELETAL MUSCLE; VASCULARIZATION;

ANIMAL; EXERTION; HUMAN; MICROCIRCULATION; MUSCLE CONTRACTION; MUSCLE, SKELETAL; OXYGEN; RATS; SYMPATHETIC NERVOUS SYSTEM; VASOMOTOR SYSTEM; ANIMALS; HUMANS;

OXYGEN;

EID: 0036000270     PISSN: 09078916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (218)

1. The muscle metaboreflex triggers parallel sympathetic activation in resting and exercising human skeletal muscle
2. The exercise pressor response to sustained handgrip does not augment blood flow in the contracting forearm skeletal muscle
3. Inhibition of alpha-2 adrenergic vasoconstriction during contraction of glycolytic, not oxidative, rat skeletal muscle
4. Differential sympathetic neural control of muscle oxygenation in resting and exercising human skeletal muscle
5. Exercise-induced attenuation of alpha-adrenoceptor mediated vasoconstriction in humans: Evidence from phase-contrast magnetic resonance imaging
6. Metabolic modulation of sympathetic vasoconstriction in human skeletal muscle: Role of tissue hypoxia
7. ATP-sensitive potassium channels mediate contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle
8. Observations in man upon a blood pressure raising reflex arising from the voluntary muscles
9. Maximal perfusion of skeletal muscle in man
10. Flow-mediated and reflex changes in large peripheral artery tone in humans
11. Differential sensitivity of arteriolar alpha 1- and alpha 2-adrenoceptor constriction to metabolic inhibition during rat skeletal muscle contraction
12. The relation of the sympathetic nervous system to the contractions and fatigue of skeletal muscle in mammals
13. Nitric oxide release is present from incubated skeletal muscle preparations
14. Autonomic innervation of receptors and muscle fibres in cat skeletal muscle
15. 2 during sympathetic escape in skeletal muscle
16. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
17. Local muscle blood flow and sustained contractions of human arm and back muscles
18. Alpha-adrenergic vasoconstriction in active skeletal muscles during dynamic exercise
19. Sympathetic vasoconstriction in active skeletal muscles during dynamic exercise
20. Alpha 1-adrenergic-receptor responsiveness in skeletal muscle during dynamic exercise
21. Antagonism of vasoconstrictor responses by exercise in the gracilis muscle of the dog
22. The role of prostaglandins in the endothelium-mediated vasodilatory response to hypoxia
23. Potassium homeostasis during and following exhaustive submaximal static handgrip contractions
24. Genetic disease of mitochondrial function evaluated by NMR and NIR spectroscopy of skeletal tissue
25. Mechanisms of metabolic inhibition of sympathetic vasoconstriction in contracting human skeletal muscle: Role of nitric oxide
26. Measurement of absolute epicardial coronary artery flow and flow reserve with breath-hold cine phase-contrast magnetic resonance imaging
27. + channels in pancreatic b-cells
28. Regulation of sarcoplasmic reticulum protein phosphorylation by localized cyclic GMP-dependent protein kinase in vascular smooth muscle cells
29. Role of adenosine in the sympathetic activation produced by isometric exercise in humans
30. Competition between vasoconstrictor and vasodilator mechanisms in skeletal muscle
31. Trigeminal and carotid body inputs controlling vascular resistance in muscle during post-contraction hyperemia in cats
32. Manoeuvres affecting sympathetic outflow in human nerves
33. Similarity of blood flow in the normal and the sympathectomized dog hind limb during graded exercise
34. Responses to dynamic leg exercise in man as influenced by changes in muscle perfusion pressure
35. Exercise hyperpnea and locomotion: Parallel activation from the hypothalamus
36. The erythrocyte as a regulator of vascular tone
37. Comparison of cerebral artery blood flow measurements with gated cine and ungated phase-contrast techniques
38. Overflow of catecholamine neurotransmitters to the circulation: Source, fate and functions
39. Microvascular response to blockade of prostaglandin synthesis in rat skeletal muscle
40. In vivo validation of MR velocity imaging
41. Finger-specific flexor recruitment in humans: Depiction by exercise-enhanced MRI
42. Impulse frequency in sympathetic vasomotor fibres correlated to the release and elimination of the transmitter
43. 2
44. Cardiovascular adjustment to somatomotor activation
45. Cardiovascular and metabolic responses to static contraction in man
46. Cardiovascular and respiratory responses to changes in central command during isometric exercise at constant muscle tension
47. The oxyhemoglobin reaction of nitric oxide
48. Role of resistance and exchange vessels in local microvascular control of skeletal muscle oxygenation in the dog
49. Attenuation of neurogenic vasoconstricion by nitric oxide in hindlimb microvascular beds of the rat in vivo
50. Exteroceptive, proprioceptive and sympathetic activity recorded with microelectrodes from human peripheral nerves
51. The exercise pressor response to sustained handgrip does not augment blood flow in the contracting forearm skeletal muscle
52. Metabolic modulation of sympathetic vasoconstriction in human skeletal muscle: Role of tissue hypoxia
53. Exercise-induced attenuation of alpha-adrenoceptor mediated vasoconstriction in humans: Evidence from phase-contrast MRI
54. Differential sympathetic neural control of oxygenation in resting and exercising humans skeletal muscle
55. Muscle metaboreflex triggers parallel sympathetic activation in exercising and resting human skeletal muscle
56. Direct measurement of sympathetic activity: New insights into disordered blood pressure regulation in chronic renal failure
57. Identification of a putative microvascular oxygen sensor
58. Respiratory muscle work compromises leg blood flow during maximal exercise
59. Effects of respiratory muscle work on cardiac output and its distribution during maximal exercise
60. Hemodynamic and metabolic effects of alpha-adrenoceptor blockade with phentolamine at rest and during forearm exercise
61. Characteristics of adrenoceptors in the human radial artery: Clinical implications
62. Effect of hypoxemia on responses to norepinephrine and angiotensin in coronary and muscular vessels
63. Effect of acute hypoxia on vascular responsiveness in man
64. Adenosine concentrations in the interstitium of resting and contracting human skeletal muscle
65. A peripheral arterial conducting mechanism underlying dilatation of the femoral artery and concerned in functional vasodilatation in skeletal muscle
66. In Vivo validation of magnetic resonance blood volume flow measurements with limited spatial resolution in small vessels
67. The blood flow through active and inactive muscles of the forearm during sustained handgrip contractions
68. Assessment of coronary flow and flow reserve in humans with magnetic resonance imaging
69. Forearm vascular responsiveness to alpha1 and alpha2-adrenoceptor stimulation in patients with congestive heart failure
70. Relative contributions of cardiopulmonary and sinoaortic baroreflexes in causing sympathetic activation in the human skeletal muscle circulation during orthostatic stress
71. Plasma potassium concentration and Doppler blood flow during and following submaximal handgrip contractions
72. Changes in forearm blood flow associated with sustained handgrip performance
73. S-nitrosohaemoglobin: A dynamic activity of blood involved in vascular control
74. Differences between exogenous and endogenous noradrenaline in the effects on vascular post-synaptic alpha 1- and alpha 2-adrenoceptors in man
75. Über die einwirkung der muskeltätigkeit auf die athmung und die hertztätigkeit
76. Does the pressor response to ischemic exercise improve blood flow to contracting muscles in humans?
77. Neurogenic vasodilation in human skeletal muscle: Possible role in contraction-induced hyperemia
78. Blood flow to contracting human muscles: Influence of increased sympathetic activity
79. 2 uptake in rhythmically contracting human forearm muscles
80. Relative contraction force producing a reduction in calf blood flow by superimposing forearm exercise on lower leg exercise
81. Brachial artery blood flow during static handgrip exercise of short duration studied by a Doppler ultrasound method
82. Exhausting handgrip exercise reduces the blood flow in the active calf muscle exercising at low intensity
83. Role of adenosine in exercise vasodilation
84. Effect of ischemia on responses of group III and IV afferents to contraction
85. Theory and Application of the exchange of inert gas at the lungs and tissues
86. The effect of exercise on the vascular bed of skeletal muscle
87. On the competition between metabolic vasodilatation and neurogenic vasoconstriction in skeletal muscle
88. Attenuation of reactive and active hyperemia by sympathetic stimulation in dog gracilis muscle
89. 2 receptors and cAMP-dependent protein kinase
90. Nitric oxide in skeletal muscle
91. Hypoxia and the cardiovascular response to dynamic knee-extensor exercise
92. Cardiovascular responses to dynamic exercise with acute anemia in humans
93. The regulation of respiration and circulation during the initial stages of muscular work
94. A tutorial on the diffusibility and reactivity of free nitric oxide
95. Prostaglandin production contributes to exercise-induced vasodilation in heart failure
96. Regulation of skeletal muscle blood flow during contractions
97. Indicator methods for measurements of organ and tissue blood flow
98. Control of blood flow to cardiac and skeletal muscle during exercise
99. Magnetic resonance imaging kappa-space segmentation using phase-encoding groups the accuracy of quantitative measurements of pulsatile flow
100. Cardiovascular adjustments to isometric contractions: Static effort
101. Local and central circulatory responses to sustained contractions and the effect of free or restricted arterial inflow on post-exercise hyperemia
102. Influence of arachidonic acid on vasoconstrictor responses in the rabbit hindquarters vascular bed
103. Femoral arterial injection of adenosine in humans elevates MSNA via central but not peripheral mechanisms
104. 2 delivery
105. Validation of near infrared spectroscopy in humans
106. Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans
107. + channels, potassium, and muscle vasodilation in the rat in systemic hypoxia
108. Blood pressure during supine exercise in idiopathic orthostatic hypotension
109. Effect of acidosis on contraction of microvascular smooth muscle by alpha 1- and alpha 2-adrenoceptors. Implications for neural and metabolic regulation
110. Effect of reduced blood flow on alpha 1- and alpha 2-adrenoceptor constriction of rat skeletal muscle microvessels
111. Effect of acidosis on alphal and alpha2 adrenoreceptor mediated vasoconstrictor responses in isolated arteries
112. Responses in muscle afferent fibres of slow conduction velocity to contractions and ischemia in the cat
113. Die unterdrückung konstriktorischer effekte im gefässgebiet des tätigen skeletmuskels
114. Role of endothelium-derived prostaglandins in hypoxia-elicited arteriolar dilation in rat skeletal muscle
115. The role of adenosine in dilator responses induced in arterioles and venules of rat skeletal muscle by systemic hypoxia
116. 31P nuclear magnetic resonance studies of high energy phosphates and pH in human muscle fatigue
117. 2+ channels by alpha1A and alpha2A adrenoceptors in vascular myocytes: Involvement of different transduction pathways
118. J.B. Wolffe memorial lecture. Neural control of the circulation during exercise
119. The exercise pressor reflex: Its cardiovascular effects, afferent mechanisms, and central pathways
120. Cardiovascular reflex control by afferent fibers from skeletal muscle receptors
121. Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels
122. Effects of diazoxide on norepinephrine-induced vasoconstriction and ischemic myocardium in rats
123. Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle
124. Alpha-stimulation protects exercise increment in skeletal muscle oxygen consumption
125. Physiological roles and properties of potassium channels in arterial smooth muscle
126. Alpha-adrenoceptors in human resistance arteries from colon, pericardial fat, and skeletal muscle
127. Interactions between alphaadrenoceptors and adenosine receptors on microvascular smooth muscle
128. Direct regulation of smooth muscle contractile elements by second messengers
129. 2 delivery to ischemic active skeletal muscle
130. Is active skeletal muscle functionally vasoconstricted during dynamic exercise in conscious dogs?
131. Baroreflex-induced vasoconstriction in active skeletal muscle of conscious dogs
132. Is the muscle metaboreflex important in control of blood flow to ischemic active skeletal muscle in dogs?
133. Interaction between microvascular alpha 1- and alpha 2-adrenoceptors and endothelium-derived relaxing factor
134. Reduced arterial diameter during static exercise in humans
135. Die sympatische innervation der skeletmuskeln
136. Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine
137. Phase contrast cine magnetic resonance imaging
138. Sympathetic neural influences on muscle blood flow in rats during submaximal exercise
139. Near Infrared Spectroscopy: Principles and application to noninvasive assessment of tissue oxygenation
140. Absorption spectroscopy for assessment of mitochondrial function in vivo
141. Development and validation of multiwavelength algorithms for in vivo near infrared spectroscopy
142. Impairment of sympathetic activation during static exercise in patients with muscle phosphorylase deficiency (McArdle's disease)
143. Cellular pharmacology of potassium channel openers in vascular smooth muscle
144. ATP channels in vascular smooth muscle
145. Cyclic guanosine monophosphate inhibition of contraction may be mediated through inhibition of phosphatidlyinositol hydrolysis in rat aorta
146. Die interferenz der vasomotorischen regulationen
147. Functional sympatholysis during muscular activity
148. High muscle blood flows are not attenuated by recruitment of additional muscle mass
149. Effect of armcranking on leg blood flow and noradrenaline spillover during leg exercise in man
150. Effect of metabolic products of muscular contraction on discharge of group III and IV afferents
151. Integration of cardiovascular control systems in dynamic exercise
152. Sympathetic vasoconstrictive responses during exercise- or drug-induced vasodilation
153. Peak muscle perfusion and oxygen uptake in humans: Importance of precise estimates of muscle mass
154. Human femoral artery diameter in relation to knee extensor muscle mass, peak blood flow, and oxygen uptake
155. Skeletal muscle tension, flow, pressure, and EMG during sustained isometric contractions in humans
156. Pulsed Doppler: Diameter, blood flow velocity and volumic flow of the brachial artery in sustained essential hypertension
157. Skeletal muscle blood flow in humans and its regulation during exercise
158. Potassium, lactate, and water fluxes in human quadriceps muscle during static contractions
159. Functional sympatholysis is attenuated in neuronal nitric oxide synthase deficient skeletal muscle of boys with Duchenne muscular dystrophy
160. Noradrenaline spillover during exercise in active versus resting skeletal muscle in man
161. Norepinephrine spillover from skeletal muscle during exercise in humans: Role of muscle mass
162. Arterial baroreflex buffering of sympathetic activation during exercise-induced elevations in arterial pressure
163. Über kreislaufregulatorische vorgänge an den grossen arterien bei der muskelarbeit
164. Sympathetic neural discharge and vascular resistance during exercise in humans
165. Regulation of muscle sympathetic nerve activity during exercise in humans
166. Central and regional circulatory effects of adding arm exercise to leg exercise
167. Cell-to-cell communication coordinates blood flow control
168. Circulatory response to exercise in health
169. Static (isometric) exercise. Retrospection and introspection
170. Does inadequate oxygen delivery trigger pressor response to muscle hypoperfusion during exercise?
171. Time course of brachial artery responses to rhythmic handgrip exercise in humans
172. Augmented sympathetic tone alters muscle metabolism with exercise: Lack of evidence for functional sympatholysis
173. Venous occlusion plethysmography on the calf
174. Skeletal muscle metaboreceptor stimulation opposes peak metabolic vasodilation in humans
175. Characteristics of flow-mediated brachial artery vasodilation in human subjects
176. Role of diprotonated phosphate in evoking muscle reflex responses in cats and humans
177. Sympathetic tone affects human limb vascular resistance during a maximal metabolic stimulus
178. Muscle blood flow during isometric activity and its relation to muscle fatigue
179. Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilation induced in the rat by acute systemic hypoxia
180. + in abolition of sympathetic vasoconstriction in dog skeletal muscle
181. Blood flow regulation by S-nitrosohemoglobin in the physiological oxygen gradient
182. The effect in humans of increased sympathetic activity on the blood flow to active muscles
183. Cardiovascular control during concomitant dynamic leg exercise and static arm exercise in humans
184. Cardiovascular responses to carotid sinus baroreceptor stimulation during moderate to severe exercise in man
185. Further evidence for the existence of alpha2-mediated adrenergic vasoconstriction in human vessels
186. Hypoxia and smooth muscle function:key regulatory events during metabolic stress
187. + channels mediate alpha 2D-adrenergic receptor contraction of arteriolar smooth muscle and reversal of contraction by hypoxia
188. Inhibition of arteriole alpha 2- but not alpha 1-adrenoceptor constriction by acidosis and hypoxia in vitro
189. Inhibition of alpha 2-adrenergic vasoconstriction during contraction of glycolytic not oxidative, rat hindlimb muscle
190. ATP-sensitive potassium channels mediate contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle
191. Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle
192. Nitric oxide mediates contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle
193. Blood flow and oxygen consumption in skeletal muscle during sympathetic stimulation
194. Calcium handling in vasoconstriction to stimulation of alpha1 and alpha2 adrenoceptors
195. Participation of endothelium-derived relaxing factor and role of cyclic GMP in inhibitory effects of endothelium on contractile responses elicited by alpha-adrenoceptor agonists in rat aorta
196. Ischemic muscle chemoreflex response elevates blood flow in nonischemic exercising human forearm muscle
197. Washout of 133-xenon after intramuscular injection and indirect measurement of blood flow in skeletal muscle
198. Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves
199. Postjunctional alpha-adrenoceptors and the regulation of arteriolar tone in humans
200. Alpha-adrenergic receptors in human blood vessels
201. Sympathetic nerve discharge is coupled to muscle cell pH during exercise in humans
202. Effects of lower body negative pressure on sympathetic discharge to leg muscles in humans
203. Reflex stimulation of sympathetic outflow during rhythmic exercise in humans
204. Central command increases muscle sympathetic nerve activity during intense intermittent isometric exercise in humans
205. Sympathetic activation in exercise is not dependent on muscle acidosis. Direct evidence from studies in metabolic myopathies
206. Differential activation of sympathetic discharge to skin and skeletal muscle in humans
207. Bewegungen des atmens und schluckens mit besonderer berucksichtigung neurologischer streitfragen
208. Quantitative aspects of blood flow and oxygen uptake in the human forearm during rhythmic exercise
209. Coherence between the sympathetic drives to relaxed and contracting muscles of different limbs of human subjects
210. Sympathetic outflow to resting muscles during static handgrip and postcontraction muscle ischemia
211. Sympathetic control of the forearm blood flow in man during brief isometric contractions
212. Purine receptors in mammalian tissues: Pharmacology and functional significance
213. Contribution of prostaglandins to exercise-induced vasodilation in humans
214. Cardiovascular responses to graded reductions in hindlimb perfusion in exercising dogs