Hypoxia and the cardiovascular response to dynamic knee-extensor exercise

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 272, Issue 6 41-6, 1997, Pages

  Koskolou, Maria D ^a,b   Calbet, José A L ^a,c   Rådegran, Göran ^a   Roach, Robert C ^a  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF ATHENS   (Greece)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

Arterial oxygen saturation; Lactate; Limb blood flow; Potassium; Stroke volume

Indexed keywords

LACTIC ACID; POTASSIUM ION;

ADULT; AEROBIC CAPACITY; ARTERIAL OXYGEN SATURATION; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; EXTENSOR MUSCLE; HEART OUTPUT; HEART STROKE VOLUME; HUMAN; HUMAN EXPERIMENT; HYPOXIA; LIMB BLOOD FLOW; MALE; MUSCLE EXERCISE; NORMAL HUMAN; OXYGEN TRANSPORT; PRIORITY JOURNAL; WORKLOAD;

EID: 0030742926     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.272.6.h2655     Document Type: Article

References (18)

1. Andersen, P., and B. Saltin. Maximal perfusion of skeletal muscle in man. J. Physiol. (Lond.) 366: 233-249, 1985.
2. Asmussen, E., and C. F. Consolazio. The circulation in rest and work on Mount Evans (4,300 m). Am. J. Physiol. 132: 555-563, 1941.
3. Åstrand, P. O., and I. Åstrand. Heart rate during muscular work in man exposed to prolonged hypoxia. J. Appl. Physiol. 13: 75-80, 1958.
4. Bigland-Ritchie, B., and N. K. Vollestad. Hypoxia and fatigue: how are they related? In: Hypoxia. The Tolerable Limits, edited by J. R. Sutton, C. S. Houston and G. Coates. Indianapolis, IN: Benchmark, 1988, p. 315-328.
5. Bouissou, P., F. Peronnet, G. Brisson, R. Helie, and M. Ledoux. Metabolic and endocrine responses to graded exercise under acute hypoxia. Eur. J. Appl. Physiol, Occup. Physiol. 55: 290-294, 1986.
6. Dill, D. B., L. G. Myhre, E. E. Phillips, and D. K. Brown. Work capacity in acute exposures to altitude. J. Appl. Physiol. 21: 1168-1176, 1966.
7. Eysmann, S. B., E. Gervino, D. E. Vatner, S. E. Katz, L. Decker, and P. S. Douglas. Prolonged exercise alters β-adrenergic responsiveness in healthy sedentary humans. J. Appl. Physiol. 80: 616-622, 1996.
8. Harder, D. R., J. Narayanan, E. K. Birks, J. F. Liard, J. D. Imig, J. H. Lombard, A. R. Lange, and R. J. Roman. Identification of a putative microvascular oxygen sensor. Circ. Res. 79: 54-61, 1996.
9. Hartley, L. H., and B. Saltin. Reduction in stroke volume and increase in heart rate after a previous heavier submaximal workload. Scand. J. Clin. Lab. Invest. 22: 217-223, 1968.
10. Jones, P. R. M., and J. Pearson. Anthropometric determination of leg fat and muscle plus bone volumes in young male and female adults. J. Physiol. (Lond.) 204: 63P-66P, 1969.
11. Klausen, K. Cardiac output in man at rest and work during and after acclimatization to 3,800 m. J. Appl. Physiol. 21: 609-616, 1966.
12. Klausen, K. Exercise under hypoxic conditions. Med. Sci. Sports 1: 43-49, 1969.
13. Koskolou, M., R. C. Roach, J. A. L. Calbet, and B. Saltin. Cardiovascular adjustments in man to low arterial oxygen content: is oxygen content, saturation or tension the regulator? (Abstract). J. Physiol. (Lond.) 495: 137P, 1996.
14. Marshall, J. M. Skeletal muscle vasculature and systemic hypoxia. News Physiol. Sci. 10: 274-280, 1995.
15. Paridon, S. M., J. T. Bricker, W. J. Dreyer, M. Reardon, E. O. Smith, C. J. Porter, L. Michael, and D. J. Fisher. The effects of hypoxemia on myocardial blood flow during exercise. Pediatr. Res. 25: 280-284, 1989.
16. Qu, Z., J. L. Andersen, and S. Zhou. Visualization of capillaries in human skeletal muscle. Histochem. Cell. Biol. 107: 169-174, 1997.
17. 2 during single leg knee-extensor exercise in humans. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1453-H1461, 1995.
18. Rowell, L. B., B. Saltin, B. Kiens, and N. J. Christensen. Is peak quadriceps blood flow in humans even higher during exercise with hypoxemia? Am. J. Physiol. 251 (Heart Circ. Physiol. 20): H1038-H1044, 1986.