Reproductive function in rats exposed neonatally to bisphenol A and estradiol benzoate

Reproductive Toxicology

Volumn 13, Issue 4, 1999, Pages 303-311

  Nagao, Tetsuji ^a   Saito, Yoshiaki ^a   Usumi, Kenji ^a   Kuwagata, Makiko ^a   Imai, Kiyoshi ^a  

^a HATANO RESEARCH INSTITUTE   (Japan)

Author keywords

Bisphenol A; Estradiol benzoate; Neonatal exposure; Reproduction; SDN POA; Sexual behavior

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; DRUG DERIVATIVE; ESTRADIOL; ESTRADIOL 3-BENZOATE; ESTRADIOL BENZOATE; ESTROGEN; PHENOL DERIVATIVE;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; COPULATION; DRUG EFFECT; EPIDIDYMIS; FEMALE; FERTILITY; GROWTH, DEVELOPMENT AND AGING; HISTOPATHOLOGY; MALE; NONHUMAN; ORGAN WEIGHT; PATHOLOGY; PREOPTIC AREA; RAT; RAT STRAIN; REPRODUCTION; REPRODUCTIVE TOXICITY; SEXUAL BEHAVIOR; SUBCUTANEOUS DRUG ADMINISTRATION; TESTIS;

ANIMALS; ANIMALS, NEWBORN; BRAIN; COPULATION; EPIDIDYMIS; ESTRADIOL; ESTROGENS, NON-STEROIDAL; FEMALE; FERTILITY; MALE; ORGAN SIZE; PHENOLS; PREOPTIC AREA; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; TESTIS;

ANIMALIA;

EID: 0033166875     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(99)00017-9     Document Type: Article

References (45)

1. Olea N., Pulgar R., Pérez P., Olea-Serrano F., Rivas A., Novillo-Fertrell A., Pedraza V., Soto A.M., Sonnenschein C. Estrogenicity of resin-based composites and sealants used in dentistry. Environ Health Perspect. 104:1996;298-305.
2. Brotons J.A., Olea-Serrano M.F., Villalobos M., Pedraza V., Olea N. Xenoestrogens released from lacquer coating in food cans. Environ Health Perspect. 103:1995;608-612.
3. Colerange J.B., Roy D. Profound effects of the weak environmental estrogen-like chemical bisphenol A on the growth of the mammary gland of Noble rats. J Steroid Biochem Mol Biol. 60:1997;153-160.
4. Von Saal F., Cooke P.S., Buchanan D.L., Palanza P., Thayer K.A., Nagel S.C., Parmigiani S., Welshons W.V. A physiologically based approach to the study of bispheno A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior . Toxicol Indust Health. 14:1998;239-260.
5. Ashby A., Tinwell H. Uterotrophic activity of bisphenol A in the immature rat. Environ Health Perspect. 106:1998;719-720.
6. Dhar J.D., Setty B.S. Epididymal response to exogenous testosterone in rats sterilized neonatally by estrogen. Endokrinologie. 68:1976;14-21.
7. Mietkiewski K., Limanowski A. Attempts at stimulation of spermatogenesis by testosterone in the rat treated with a single dose of stilboestrol on the first day of life. Folia Histochem Cytochem (Krakow). 12:1974;255-260.
8. Ohta Y. Response of testis to androgen and gonadotropins in neonatally estrogenized and androgenized mice. Endocrinol Jpn. 24:1977;287-294.
9. Kincl F.A., Folch-Pi A., Maqueo M., Herrera-Lasso L., Oriol A., Dorfman R.I. Inhibition of sexual development in male and female rats treated with various steroids at the age of five days. Acta Endocrinol. 49:1965;193-206.
10. Ostadolova I., Loyda Z., Parizek J. The effect of gonadotropins on the metabolic activity of the testicular Leydig cells in normal infantile rats and in rat pretreated postnatally by estrogens. Physiologia Bohemoslovaca. 16:1967;477-487.
11. Aguilar E., Tejero A., Vaticon M.D., Fernandez-Galaz C. Dissociation of luteinizing hormone and follicle-stimulating hormone control mechanisms in male and female rats by neonatal administration of estradiol benzoate or testosterone propionate. Horm Res. 19:1984;108-116.
12. Ota Y., Takasugi N. Ultrastructural changes in the testis of mice given neonatal injections of estrogen. Endocrinol Jpn. 21:1974;183-190.
13. Jacobson C.D., Gorski R.A. Neurogenesis of the sexually dimorphic nucleus of the preoptic area in the rat. J Comp Neurol. 196:1981;519-529.
14. Döhler K.D. The pre- and postnatal influence of hormones and neurotransmitters on sexual differentiation of the mammalian hypothalamus. Int Rev Cytol. 131:1991;1-57.
15. Heimer L, Larsson K. Impairment of mating behavior in male rats following lesions in the preoptic-anterior hypothalamic continuum. Brain Res 1966;67;3:248-63.
16. Lisk R.D. Inhibitory centers in sexual behavior in the male rat. Science. 152:1966;669-670.
17. Giantonio G.W., Lund N.L., Gerall A.A. Effect of diencephalic and rhinencephalic lesions on the male rat's sexual behavior. J Comp Physiol Psychol. 73:1970;38-46.
18. Ginton A., Merari A. Long range effects of MPOA lesion on mating behavior in the male rat. Brain Res. 120:1977;158-163.
19. Vaughan E., Fisher A.E. Male sexual behavior induced by intracranial electrical stimulation. Science. 137:1962;758-760.
20. van Dis H., Larsson K. Induction of sexual arousal in the castrated male rat by intracranial stimulation. Physiol Behav. 6:1971;85-86.
21. Malsbury C.W. Facilitation of male rat copulatory behavior by electrical stimulation of the medial preoptic area. Physiol Behav. 7:1971;797-805.
22. Merari A., Ginton A. Characteristics of exaggerated sexual behavior induced by electrical stimulation of the medial preoptic area in male rats. Brain Res. 86:1975;97-108.
23. Iguchi T., Ohta Y. Cellular effects of early exposure to tamoxifen. Kellen J.A. Tamoxifen beyond the antiestrogen . 1995;179-200 Birkhauser, Boston.
24. Siegel S. Nonparametric statistics for the behavioral sciences. 1956;McGraw-Hill, New York.
25. Kincl F.A., Folch A., Lasso L.H. Effect of estradiol benzoate treatment in the newborn male rat. Endocrinol. 72:1963;966-968.
26. Kent H.A. Polyovular follicles and multinucleate ova in the ovaries of young mice. Anat Rec. 137:1960;521-524.
27. Iguchi T., Takasugi N., Bern H.A., Mills K.T. Frequent occurrence of polyovular follicles in ovaries of mice exposed neonatally to diethylstilbestrol. Teratology. 34:1986;29-35.
28. Hartman C.G. Polynuclear ova and polyovular follicles in the opossum and other mammals, with special reference to the problem of fecundity. Am J Anat. 37:1926;1-51.
29. Kent H.A. Reduction of polyovular follicles and polynuclear ova by estradiol monobenzoate. Anat Rec. 134:1959;455-462.
30. Ben-Jonathan N., Steinmetz R. Xenoestrogens. The emerging story of bisphenol A. Trends Endocrinol Metabol. 9:1998;124-128.
31. Morrissey R.E., George J.D., Price C.J., Tyl R.W., Marr M.C., Kimmel C.A. The developmental toxicity of bisphenol A in rats and mice. Fundam Appl Toxicol. 8:1987;571-582.
32. Environmental Protection Agency. Reproduction and fertility effects. Health effect test guidelines. EPA Publication No. 560/6-82-001, National Technical Information Service, Publication No. PB82-232984 (1982a).
33. Environmental Protection Agency. Pesticide assessment guidelines. Subdivision F, hazard evaluation: Human and domestic animals. EPA Publication No. 540/9-82-025, National Technical Information Service No. PB83-153916 (1982b).
34. Morrissey R.E., Lamb J.C., Morris R.W., Chapin R.E., Gulati D.K., Heindel J.J. Results and evaluations of 48 continuous breeding reproduction studies conducted in mice. Fundam Appl Toxicol. 13:1989;747-777.
35. Bullock B.C., Newbold R.R., McLachlan J.A. Lesions of the testis and epididymis associated with prenatal diethylstilbestrol exposure. Environ Health Perspect. 77:1988;29-31.
36. Gorski R.A. Gonadal hormones and the perinatal development of neuroendocrine function. Martini L., Gonang W.F. Frontiers in neuroendocrinology. 1971;237-290 Oxford University Press, New York.
37. Yasuda Y., Konishi H., Matsuo T., Tanimura T. Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol. Anat Embryol. 174:1986;289-299.
38. Gorski R.A., Gordon J.H., Shryne J.E., Southam A.M. Evidence for a morphological sex difference within the medial preoptic area of the rat brain. Brain Res. 148:1978;333-346.
39. MacLusky N.J., Naftolin F. Sexual differentiation of the central nervous system. Science. 211:1981;1294-1303.
40. Handa R.J., Corbier P., Shryne J.E., Schoonmaker J.N., Gorski R.A. Differential effects of the perinatal steroid environment on three sexually dimorphic parameters of the rat brain. Biol Reprod. 32:1985;855-864.
41. Jacobson C.D., Gorski R.A. Neurogenesis of the sexually dimorphic nucleus of the preoptic area of the rat. J Comp Neurol. 196:1981;519-529.
42. Soulairac A., Soulairac M-L. Effects de lésions hypothalamiques sur le comportement sexuel et le tractus génital du rat male. Ann Endocr (Paris). 17:1956;731-745.
43. Vancutsem P.M., Roessler M. Neonatal treatment with tamoxifen causes immediate alterations of the sexually dimorphic nucleus of the preoptic area and medial preoptic area in male rats. Teratology. 56:1997;220-228.
44. Arai Y., Sekine Y., Murakami S. Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats. Neurosci Res. 25:1996;403-407.
45. Bedford J.M. Anatomical evidence for the epididymis as the prime mover in the evolution of the scrotum. Am J Anat. 152:1978;483-507.