A novel mechanism of fluconazole resistance associated with fluconazole sequestration in Candida albicans isolates from a myelofibrosis patient

Microbiology and Immunology

Volumn 46, Issue 5, 2002, Pages 317-326

  Maebashi, Kazunori ^a   Kudoh, Michinari ^a   Nishiyama, Yayoi ^a   Makimura, Koichi ^a   Uchida, Katsuhisa ^a   Mori, Takeshi ^b   Yamaguchi, Hideyo ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Candida albicans; Fluconazole sequestration; Myelofibrosis; Resistance mechanism

Indexed keywords

ANTIFUNGAL AGENT; CARRIER PROTEIN; CDR1 PROTEIN, CANDIDA ALBICANS; CYTOCHROME P450; ERGOSTEROL; FLUCONAZOLE; FUNGAL PROTEIN; FUNGAL RNA; GLYCOPROTEIN P; LANOSTEROL 14 ALPHA-DEMETHYLASE; OXIDOREDUCTASE; STEROL 14ALPHA DEMETHYLASE; AMPHOTERICIN B; FLUCYTOSINE; ITRACONAZOLE; KETOCONAZOLE;

ANTIBIOTIC RESISTANCE; ARTICLE; BIOSYNTHESIS; CANDIDA ALBICANS; CANDIDIASIS; CHEMISTRY; ELECTRON MICROSCOPY; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MYELOFIBROSIS; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPHEROPLAST; ULTRASTRUCTURE; CELL ULTRASTRUCTURE; CELL VACUOLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; ENZYME ACTIVITY; ENZYME BINDING; FUNGUS ISOLATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; STEROIDOGENESIS;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG RESISTANCE, FUNGAL; ERGOSTEROL; FLUCONAZOLE; FUNGAL PROTEINS; HUMANS; MEMBRANE TRANSPORT PROTEINS; MICROSCOPY, ELECTRON; MYELOFIBROSIS; OXIDOREDUCTASES; P-GLYCOPROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, FUNGAL; SPHEROPLASTS; HUMAN;

CANDIDA; CANDIDA ALBICANS; FUNGI;

EID: 0035992656     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2002.tb02702.x     Document Type: Article

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