Vitamin E-modified filters modulate Jun N-terminal kinase activation in peripheral blood mononuclear cells

Kidney International

Volumn 62, Issue 2, 2002, Pages 602-610

  Pertosa, Giovanni ^a   Grandaliano, Giuseppe ^a   Soccio, Michela ^a   Martino, Carmela ^a   Gesualdo, Loreto ^a   Schena, Francesco Paolo ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Biocompatibility; Dialysis membranes; Hemodialysis; Intracellular signaling; Jun N terminal kinase; Mononuclear cells; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; COMPLEMENT MEMBRANE ATTACK COMPLEX; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; NOS2A PROTEIN, HUMAN; STRESS ACTIVATED PROTEIN KINASE; CELLULOSE ACETATE; ENZYME ANTIBODY; JUN N TERMINAL KINASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ARTIFICIAL MEMBRANE; BIOSYNTHESIS; CHRONIC KIDNEY FAILURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; IN VITRO STUDY; LEUKOCYTE COUNT; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; MONONUCLEAR CELL; PHOSPHORYLATION; RANDOMIZED CONTROLLED TRIAL; RENAL REPLACEMENT THERAPY; ANTIGEN RECOGNITION; CELL ACTIVATION; CELL ISOLATION; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HEMODIALYSIS; MEMBRANE FILTER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UREMIA; WESTERN BLOTTING;

ADULT; AGED; ANTIOXIDANTS; COMPLEMENT MEMBRANE ATTACK COMPLEX; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY FAILURE, CHRONIC; LEUKOCYTE COUNT; LEUKOCYTES, MONONUCLEAR; MALE; MEMBRANES, ARTIFICIAL; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; RENAL DIALYSIS; VITAMIN E;

EID: 0035991559     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00458.x     Document Type: Article

References (40)

1. Enhancement of reactive oxygen species production and cell surface markers expression due to hemodialysis
2. Cytokines and bioincompatibility
3. Transmembrane receptors and intracellular pathways that control cell proliferation
4. Regulation of lymphocyte function by protein phosphorylation
5. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
6. The Jak-STAT pathway
7. T cell antigen receptor activation pathways: The tyrosine kinase connection
8. T cell antigen receptor-mediated activation of the Ras/mitogen-activated protein kinase pathway controls interleukin 4 receptor function and type-2 helper T cell differentiation
9. Membrane signaling by complement C5b-9, the membrane attack complex
10. 2 in glomerular epithelial cells
11. Complement activates phospholipases and protein kinases in glomerular epithelial cells
12. Activation of Ras and mitogen-activated protein kinase pathway by terminal complement complexes is G protein dependent
13. Oxidant stress in hemodialysis
14. Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases
15. c-src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase-1
16. Syk-dependent and-independent signaling cascades in B cells elicited by osmotic and oxidative stress
17. Oxidative stress induces tyrosine phosphorylation of PDGF alpha and beta receptors and pp60 c-src in mesangial cells
18. The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signalling pathways on cell survival
19. Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver
20. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-jun activation domain
21. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
22. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
23. Endothelial cell inflammatory responses to tumor necrosis factor α
24. The role of Jun, Fos and AP-1 complex in cell proliferation and transformation
25. Bioreactivity and biocompatibility of a vitamin E-modified multilayer hemodialysis filter
26. Effect of vitamin E-bonded membrane on the 8-hydroxy 2′-deoxyguanosine level in leukocyte DNA of hemodialysis patients
27. Prospective crossover trial of the influence of vitamin E-coated dialyzer membranes on T-cell activation and cytokine induction
28. Interleukin-6, interleukin-8 and monocyte chemotactic peptide-1 gene expression and protein synthesis are independently modulated by hemodialysis membranes
29. Inducible NO synthase: Role in cellular signalling
30. Nitric oxide and macrophage function
31. Clinical relevance of cytokine production in hemodialysis
32. Metabolism of complement factor D in renal failure
33. S protein (Vitronectin) in hemodialysis patients
34. C5b-9 generation and cytokine production in hemodialyzed patients
35. The terminal complement complex C5b-9 stimulates interleukin-6 production in human smooth muscle cells through activation of transcription factors NF-κB and AP-1
36. Selective interaction of JNK protein kinase isoforms with transcription factors
37. Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP-1) cells
38. c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation
39. Both p38-alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells
40. Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites