Nucleotide alteration of retinoblastoma protein-interacting zinc finger gene, RIZ, in human leukemia

Tohoku Journal of Experimental Medicine

Volumn 196, Issue 3, 2002, Pages 193-201

  Sasaki, Osamu ^a   Meguro, Kuniaki ^a   Tohmiya, Yasuo ^a   Funato, Tadao ^a   Shibahara, Shigeki ^a   Sasaki, Takeshi ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Gene mutation; Human leukemia; RIZ; SNP; Tumor suppressor gene

Indexed keywords

ADENINE; ASPARTIC ACID; DNA BINDING PROTEIN; GLUTAMINE; METHYLTRANSFERASE; NUCLEAR PROTEIN; RETINOBLASTOMA PROTEIN; THYMINE; ZINC FINGER PROTEIN; HISTONE LYSINE METHYLTRANSFERASE; PRDM2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BASE PAIRING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FRAMESHIFT MUTATION; GENE DELETION; GENETIC ANALYSIS; GENETIC CODE; HOMOZYGOSITY; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL LINE; LEUKEMOGENESIS; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; SRC HOMOLOGY DOMAIN; T CELL LEUKEMIA; TUMOR SUPPRESSOR GENE; GENETIC POLYMORPHISM; GENETICS; METABOLISM; MUTATION; TUMOR CELL CULTURE; CELL CULTURE;

ALLELES; DNA-BINDING PROTEINS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; LEUKEMIA; MUTATION; NUCLEAR PROTEINS; POLYMORPHISM, GENETIC; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; ZINC FINGERS;

EID: 0035991441     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.196.193     Document Type: Article

References (35)

1. The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action
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3. The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein
4. Physical mapping of the retinoblastoma interacting zinc finger gene RIZ to D1S228 on chromosome 1p36
5. In vitro analysis of the E1A-homologous sequences of RIZ
6. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis
7. Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas
8. Rearrangements of chromosome band 1p36 in non-Hodgkin's lymphoma
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10. Mapping of a minimal deleted region in human hepatocellular carcinoma to 1p36. 13-p36.23 and mutational analysis of the RIZ (PRDM2) gene localized to the region
11. Microsatellite instability as a potential marker for poor prognosis in adult T cell leukemia/lymphoma
12. RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis
13. A common variant of the endothelial nitric oxide synthase (Glu298→Asp) is a major risk factor for coronary artery disease in the UK
14. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression
15. Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines
16. Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1
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23. cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene
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26. Regulation of chromatin structure by site-specific histone H3 methyltransferases
27. RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum
28. Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines
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35. Microsatellite instability and p53 mutations are associated with abnormal expression of the MSH2 gene in adult acute leukemia