A novel approach to the synthesis of EGF-like domains: A method for the one-pot regioselective formation of the three disulfide bonds of a human blood coagulation factor VII EGF-1 analogue

Journal of Peptide Research

Volumn 60, Issue 2, 2002, Pages 121-127

  Husbyn, Mette ^a   Cuthbertson, A ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Acm; Disulfide formation; EGF domain; Factor VII; Peptide synthesis; Regioselective

Indexed keywords

BLOOD CLOTTING FACTOR 7; EPIDERMAL GROWTH FACTOR DERIVATIVE; ASPARTIC ACID; ASPARTIMIDE; CYSTEINE; DISULFIDE; DRUG DERIVATIVE; EPIDERMAL GROWTH FACTOR; PEPTIDE;

AMINO ACID SUBSTITUTION; ARTICLE; DISULFIDE BOND; DRUG ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IC 50; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMISTRY; CIRCULAR DICHROISM; DRUG ANTAGONISM; ELECTROSPRAY MASS SPECTROMETRY; METHODOLOGY; MOLECULAR GENETICS; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINO ACID SEQUENCE; ASPARTIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; CYSTEINE; DISULFIDES; EPIDERMAL GROWTH FACTOR; FACTOR VII; HUMAN; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; HUMANS;

EID: 0035991350     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2002.20991.x     Document Type: Article

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