Chemical synthesis of human protein s thrombin-sensitive module and first epidermal growth factor module

Biopolymers

Volumn 46, Issue 2, 1998, Pages 53-63

  Hackeng, Tilman M ^a   Dawson, Philip E ^a   Kent, Stephen B H ^a,b   Griffin, John H ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Gryphon Therapeutics   (United States)

Author keywords

Activated protein C; Blood coagulation; Coagulation factors va and viiia; First epidermal growth factor module; Human plasma protein S; Thrombin sensitive region

Indexed keywords

AMINO ACIDS; BLOOD; CHEMICAL BONDS; COAGULATION; MOLECULAR STRUCTURE; POLYPEPTIDES; SYNTHESIS (CHEMICAL);

ACTIVATED PROTEIN C; BLOOD COAGULATION; FIRST EPIDERMAL GROWTH FACTOR MODULE; HUMAN PLASMA PROTEIN S; THROMBIN SENSITIVE REGION;

PROTEINS;

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 8A; CYSTEINE; DEUTERIUM; EPIDERMAL GROWTH FACTOR; HYDROFLUORIC ACID; PROTEIN S; RECOMBINANT PROTEIN; SOLVENT; THROMBOSPONDIN;

ANTICOAGULATION; ARTICLE; CIRCULAR DICHROISM; DISULFIDE BOND; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; PEPTIDE SYNTHESIS; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; EPIDERMAL GROWTH FACTOR; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN FOLDING; PROTEIN S; THROMBIN;

EID: 0032145758     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0282(199808)46:2<53::aid-bip1>3.0.co;2-w     Document Type: Article

References (37)

1. Griffin, J. H., Gruber, A. & Fernández, J. A. (1992) Blood 79, 3203-3211.
2. Walker, F. J. (1980) J. Biol. Chem. 255, 5521-5524.
3. Gardiner, J. E., McGann, M. A., Berridge, C. W., Fulcher, C. A., Zimmerman, T. S. & Griffin, J. H. (1984) Circulation 70, 205a.
4. Lundwall, Å., Dackowski, W., Cohen, E., Shaffer, M., Mahr, A., Dahlbäck, B., Stenflo, J. A. & Wydro, R. (1986) Proc. Natl. Acad. Sci. USA 83, 6716-6720.
5. Koedam, J. A., Meijers, J. C. M., Sixma, J. J. & Bouma, B. N. (1988) J. Clin. Invest. 82, 1236-1243.
6. Rosing, J., Hoekema, L., Nicolaes, G. A. F., Thomassen, M. C. L. G. D., Hemker, H. C., Varadi, K., Schwarz, H. P. & Tans, G. (1995) J. Biol. Chem. 270, 27852-27858.
7. Heeb, M. J., Mesters, R. M., Tans, G., Rosing, J. & Griffin, J. H. (1993) J. Biol. Chem. 268, 2872-2877.
8. Heeb, M. J., Rosing, J., Bakker, H. M., Fernández, J. A., Tans, G. & Griffin, J. H. (1994) Proc. Natl. Acad. Sci. USA 9, 2728-2732.
9. Hackeng, T. M., van't Veer, C., Meijers, J. C. M. & Bouma, B. N. (1994) J. Biol. Chem. 269, 21051-21058.
10. van't Veer, C., Hackeng, T. M., Biesbroek, D., Sixma, J. J. & Bouma, B. N. (1995) Blood 85, 1815-1821.
11. Dahlbäck, B. & Stenflo, J. A. (1981) Proc. Natl. Sci. USA 78, 2512-2516.
12. Dahlbäck, B. (1983) Biochem. J. 209, 847-856.
13. García de Frutos, P., Alim, R. I. M., Härdig, Y., Zoller, B. & Dahlbäck, B. (1994) Blood 84, 815-822.
14. Dahlbäck, B. (1983) Biochem. J. 209, 837-846.
15. Suzuki, K., Nishioka, J. & Hashimoto, S. (1983) J. Biol. Chem. 94, 699-705.
16. Walker, F. J. (1984) J. Biol. Chem. 259, 10335-10339.
17. Dahlbäck, B., Lundwall, Å. & Stenflo, J. A. (1986) J. Biol. Chem. 261, 5111-5115.
18. Chang, G. T. G., Aaldering, L., Hackeng, T. M., Reitsma, P. H., Bertina, R. M. & Bouma, B. (1994) Thromb. Haemost. 72, 693-697.
19. Dahlbäck, B., Hildebrand, B. & Malm, J. (1990) J. Biol. Chem. 265, 8127-8135.
20. He, X., Shen, L. & Dahlbäck, B. (1995) Eur. J. Biochem. 227, 433-440.
21. Stenberg, Y., Julenius, K., Dahlqvist, I., Drakenberg, I. & Stenflo, J. (1997) Eur. J. Biochem. 248, 163-170.
22. Schnölzer, M., Alewood, P., Jones, A., Alewood, D. & Kent, S. B. H. (1992) Int. J. Pept. Protein Res. 40, 180-193.
23. Sarin, V. K., Kent, S. B. H., Tam, J. P. & Merrifield, R. B. (1981) Anal. Biochem. 117, 147-157.
24. Yang, Y., Sweeney, W. V., Schneider, K., Chait, B. T. & Tam, J. P. (1994) Protein Sci. 3, 1267-1275.
25. Schmid, F. X. (1991) in Protein Structure, a Practical Approach, Creighton, T. E., Ed., IRL Press, Oxford, UK, pp. 251-285.
26. Chen, Y. H., Yang, J. T. & Chau, K. H. (1974) Biochemistry 13, 3350-3359.
27. Yang, J. Y., Wu, C. S. C. & Martinez, H. M. (1986) Methods Enzymol. 130, 228.
28. Chowdhury, S. K., Katta, V. & Chait, B. T. (1990) J. Am. Chem. Soc. 112, 9012-9013.
29. Loo, J. A., Edmonds, C. G., Udseth, H. R. & Smith, R. D. (1990) Anal. Chem. 62, 693-698.
30. Brandstetter, H., Bauer, M., Huber, R., Lollar, P. & Bode, W. (1995) Proc. Natl. Acad. Sci. USA 92, 9796-9800.
31. Hackeng, T. M., Dawson, P. E., Kent, S. B. H. & Griffin, J. H. (1995) Thromb. Haemost. 73, 1257.
32. Hackeng, T. M., Dawson, P. E., Kent, S. B. H. & Griffin, J. H. (1995) Thromb. Haemost. 73, 1253.
33. Meijer-Huizinga, F., Mertens, K. & van Mourik, J. A. (1994) Thromb. Haemost. 72, 408-414.
34. Hommel, U., Harvey, T. S., Driscoll, P. C. & Campbell, I. D. (1992) J. Mol Biol. 227, 271-282.
35. Banner, D. W., D'Arcy, A., Chène, C., Winkler, F. K., Guha, A., Konigsberg, W. H., Nermerson, Y. & Kirchhofer, D. (1996) Nature 380, 41-46.
36. Padmanabhan, K., Padmanabhan, K. P., Tulinsky, A., Park, C. H., Bode, W., Blankenship, D. T., Cardin, A. D. & Kisiel, W. (1993) J. Mol. Biol. 232, 947-966.
37. Mather, T., Oganessyan, V., Hof, P., Huber, R., Foundling, S., Esmon, C. & Bode, W. (1996) EMBO J. 15, 6822-6831.