Localization of mouse hepatitis virus open reading frame 1A derived proteins

Journal of NeuroVirology

Volumn 4, Issue 6, 1998, Pages 594-605

  Bi, Weizhen ^a   Piñón, Josefina D ^b   Hughes, Scott ^b,e   Bonilla, Pedro J ^b,f   Holmes, Kathryn V ^c   Weiss, Susan R ^b   Leibowitz, Julian L ^d  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Coronavirus; Protein trafficking; Proteolytic protein processing

Indexed keywords

ANTISERUM; FLUORESCENT DYE; MONOCLONAL ANTIBODY; POLYPEPTIDE;

ARTICLE; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION; GENE SEQUENCE; GOLGI COMPLEX; IMMUNOFLUORESCENCE TEST; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; OPEN READING FRAME; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PROCESSING; VACCINIA VIRUS;

CORONAVIRUS; MURINAE; MURINE HEPATITIS VIRUS; VACCINIA; VACCINIA VIRUS;

EID: 0032421665     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289809114226     Document Type: Article

References (47)

1. Baker SC, Shieh C-K, Soe LH, Chang M-F, Vannier DM, Lai MMC (1989). Identification of a domain required for autoproteolytic cleavage of murine coronavirus gene A polyprotein. J Virol 63: 3693-3699.
2. Baker SC, Yokomori K, Dong S, Carlisle R, Gorbalenya AE, Koonin EV, Lai MMC (1993). Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus. J Virol 67: 6056-6063.
3. Bienz K, Egger D, Pfister T, Troxler M (1992). Structural and functional characterization of poliovirus replication complex. J Virol 66: 2740-2747.
4. Bonilla PJ, Gorbalenya AE, Weiss SR (1994). Mouse hepatitis virus strain A59 RNA polymerase gene ORF1a, Heterogeneity among MHV strains. Virology 198: 736-740.
5. Bonilla PJ, Hughes SA, Piñón JD, Weiss SR (1995). Characterization of the leader papain-like proteinase of MHV-A59, identification of a new in vitro cleavage site. Virology 209: 489-497.
6. Bonilla PJ, Hughes SA, Weiss SR (1997). Characterization of a second cleavage site and demonstration of activity in trans by the papain-like proteinase of the murine coronavirus mouse hepatitis virus strain A59. J Virol 71: 900-909.
7. Brayton PR, Lai MMC, Patton CD, Stohlman SA (1982). Characterization of two RNA polymerase activities induced by mouse hepatitis virus. J Virol 42: 847-853.
8. Breedenbeek PJ, Pachuk CJ, Noten AFH, Charité J, Luyjtes W, Weiss SR, Spaan WJM (1990). The primary structure and expression of the second open reading frame of the polymerase gene of the coronavirus MHV-A59; a highly conserved polymerase is expressed by an efficient ribosomal frameshifting mechanism. Nucleic Acids Res 18: 1825-1832.
9. Burke B, Griffiths G, Reggio H, Louvard D, Warren G (1982). A monoclonal antibody against a 135-K Golgi membrane protein. EMBO J 1: 1621-1628.
10. Burks JS, DeVald BL, Jankovsky LD, Gerdes JC (1980). Two coronaviruses isolated from central nervous tissue of two multiple sclerosis patients. Science 209: 933-934.
11. Collins AR, Knobler RL, Powell H, Buchmeier MJ (1982). Monoclonal antibodies to murine hepatitis virus-4 (strain JHM) define the viral glycoprotein responsible for attachment and cell-cell fusion. Virology 119: 58-71.
12. den Boon JA, Snijder EJ, Chirnside ED, de Vries AA, Horzinek MC, Spaan WJ (1991). Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily. J Virol 65: 2910-2920.
13. Denison MR, Perlman S (1986). Translation and processing of mouse hepatitis virus virion RNA in a cell-free system. J Virol 60: 12-18.
14. Denison MR, Perlman S (1987). Identification of a putative polymerase gene product in cells infected with murine coronavirus A59. Virology 157: 565-568.
15. Denison MR, Zoltick PW, Leibowitz JL, Pachuk CJ, Weiss SR (1991). Identification of polypeptides encoded in ORF1b of the putative polymerase gene of the murine coronavirus MHV-A59. J Virol 65: 3076-3082.
16. Denison MR, Zoltick PW, Hughes SA, Giangreco B, Olson AL, Perlman S, Leibowitz JL, Weiss SR (1992). Intracellular processing of the N-terminal ORF1a proteins of the coronavirus MHV-A59 requires multiple proteolytic events. Virology 189: 274-284.
17. Denison MR, Hughes SA, Weiss SR (1995). Identification and characterization of a 65-kDa protein processed from the gene 1 of the murine coronavirus MHV-A59. Virology 207: 316-320.
18. Dubois-Dalcq M, Holmes KV, Rentier P (1984). Assembly of RNA Viruses, pp. 100-119. Springer-Verlag, Wien, Austria and New York, NY.
19. Dveksler GS, Pensiero MN, Cardelluchio CB, Williams RK, Jiang GS, Holmes KV, Dieffenbach CW (1991). Cloning of the mouse hepatitis virus (MHV) receptor, expression in human and hamster cell lines confers susceptibility to MHV. J Virol 65: 6881-6891.
20. Fleming JO, Shubin RA, Sussman MA, Casteel N, Stohlman SA (1989). Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis. Virology 168: 162-167.
21. Fuerst T, Earl P, Moss B (1987). Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes. Mol Cell Biol 7: 2538-2544.
22. Holmes KV, Doller EW, Behnke JN (1981). Analysis of the functions of coronavirus glycoproteins by differential inhibition of synthesis with tunicamycin. Adv Exp Med Biol 142: 133-142.
23. Hughes SA, Bonilla P, Denison MR, Leibowitz JL, Baric RS, Weiss SR (1993). A newly identified MHV-A59 ORF1a polypeptide p65 is temperature sensitive in two RNA negative mutants. Adv Exp Med Biol 342: 221-226.
24. Hughes SA, Bonilla PJ, Weiss SR (1995). Identification of the murine coronavirus p28 cleavage site. J Virol 69: 809-813.
25. Krijnse-Locker J, Ericsson M, Rottier PJ, Griffiths G (1994). Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step. J Cell Biol 124: 55-70.
26. Lavi E, Gilden DH, Wrobleska Z, Rorke LB, Weiss SR (1984). Experimental demyelination produced by the A59 strain of mouse hepatitis virus. Neurology 34: 597-603.
27. Lee H-J, Shieh C-K, Gorbalenya AE, Koonin EV, LaMonica N, Tuler J, Bagdzhadzhyan A, Lai MMC (1989). The complete sequence (22 kilobases) of murine coronavirus gene-1 encoding the putative proteases and RNA polymerase. Virology 180: 567-582.
28. Leibowitz JL, Wilhelmsen KC, Bond CW (1981). The virus-specific intracellular RNA species of two murine coronaviruses, MHV-A59 and MHV-JHM. Virology 114: 39-51.
29. Leibowitz JL, DeVries JR, Haspel MV (1982). Genetic analysis of murine hepatitis virus strain JHM. J Virol 42: 1080-1087.
30. Lu Y, Lu X, Denison MR (1995). Identification and characterization of a serine-like proteinase of the murine coronavirus MHV-A59. J Virol 69: 3554-3559.
31. Lu Y, Denison MR (1997). Determinants of muse hepatitis virus 3C-like proteinase activity. Virology 230: 335-342.
32. Miller ML, Brown DT (1993). The distribution of Sinbis virus proteins in mosquito cells as determined by immunofluorescence and immunoelectron microscopy. J Gen Virol 74: 293-298.
33. Murray RS, Brown B, Brian D, Cabirac GF (1992). Detection of coronavirus RNA and antigen in multiple sclerosis brain. Ann Neurol 31: 525-533.
34. Piñón JD, Mayreddy RR, Turner JD, Khan FS, Bonnila PJ, Weiss SR (1997). Efficient autoproteolytic processing of the MHV-A59 3C-like proteinase from the flanking hydrophobic domains requires membranes. Virology 230: 309-322.
35. Rosenberg AH, Lade BN, Chui D-S, Lin S-W, Dunn JJ, Studier FW (1987). Vectors for selective expression of cloned DNAs by T7 RNA polymerase. Gene 56: 125-135.
36. Siddell SG, Wege H, ter Meulen V (1983). The biology of coronaviruses. J Gen Virol 64: 761-77.
37. Spaan WJ, Cavanagh D, Horzinek MC (1988). Coronaviruses, structure and genome expression. J Gen Virol 69: 2939-2952.
38. Stalcup RP, Baric RS, Leibowitz JL (1998). Genetic complementation amongst three panels of mouse hepatitis virus gene 1 mutants. Virology 241: 112-121.
39. Studier FW, Rosenberg AH, Dunn JJ, Dubendorff JW (1990). Use of T7 RNA polymerase to direct expression of cloned genes. Methods in Enzymology 185: 60-89.
40. Talbot PJ, Ekande S, Cashman NR, Mounir S, Stewart JN (1993). Neurotropism of human coronavirus 229E. Adv Exp Med Biol 342: 339-346.
41. Tanaka R, Iwasaki Y, Koprowski H (1976). Ultrastructural studies of perivascular cuffing cells in multiple sclerosis brain. J Neurol Sci 28: 121-126.
42. Takeda N, Kuhn RJ, Yang CF, Takegami T, Wimmer E (1986). Initiation of poliovirus plus-strand RNA synthesis in a membrane complex of infected HeLa cells. J. Virol. 60: 43-53.
43. Tooze J, Tooze S, Warren G (1984). Replication of coronavirus MHV-A59 in sac-cells: determination of the first site of budding of progeny virions. Eur J Cell Biol 33: 281-293.
44. van Dinten LC, Wassenaar AL, Gorbalenya AE, Spaan WJ, Snijder EJ (1996). Processing of the equine arteritis virus replicase ORF1b protein: identification of cleavage products containing the putative viral polymerase and helicase domains. J Virol 70: 6625-6633.
45. Weiner LP (1973). Pathogenesis of demyelination induced by a mouse hepatitis virus (JHM virus). Arch. Neurol. 28: 298-303.
46. Yu X, Bi W, Weiss SR, Leibowitz JL (1994). Mouse hepatitis gene 5b protein is a new virion envelope protein. Virology 202: 1018-1023.
47. Zoltick PW, Leibowitz JL, Oleszak EL, Weiss SR (1990). Mouse hepatitis virus ORF2a is expressed in the cytosol of infected mouse fibroblasts. Virology 174: 605-607.