Phorbol ester, but not ischemic preconditioning, activates protein kinase D in the rat heart

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 8, 1997, Pages 2273-2283

  Brooks, Gavin ^a   Goss, Martin W ^a   Rozengurt, Enrique ^b   Galiñanes, Manuel ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Cardioprotection; Ischemia; Phosphorylation; Signal transduction

Indexed keywords

ADENOSINE TRIPHOSPHATE; PHORBOL 12 ACETATE 13 MYRISTATE; PHORBOL ESTER; PHOSPHORUS 32; PROTEIN KINASE; PROTEIN KINASE D; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; CONDITIONING; CONTROLLED STUDY; ENZYME ACTIVATION; HEART; HEART LEFT VENTRICLE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HOMOGENATE; IMMUNOPRECIPITATION; MALE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TIME; VOLKMANN CONTRACTURE;

ANIMALIA;

EID: 0031214722     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1997.0466     Document Type: Article

References (30)

1. BRADFORD MM, 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
2. BROOKS G, HEARSE DJ, 1996. Role of protein kinase C in ischemic preconditioning: player or spectator? Circ Res 79: 627-630.
3. BROOKS G, GOSS MW, EAST JA, HART IR, 1993. Growth of melanocytic cells is associated with down-regulation of protein kinase C α, δ and ε isoforms. Possible role of diacylglycerol. J Biol Chem 268: 23868-23875.
4. BRUDER JT, HEIDECKER G, RAPP UR, 1992. Serum-, TPA-, and Ras-induced expression from AP-1/Ets-driven promoters requires Raf-1 kinase. Genes Dev 6: 545-556.
5. COHEN MV, DOWNEY JM, 1993. Ischaemic preconditioning: can the protection be bottled? The Lancet 342: 6.
6. GALIÑANES M, MCGILL C, BROOKS G, HEARSE DJ, 1996. Can the protein kinase C activator diacylglycerol precondition the rat heart? J Mol Cell Cardiol 28: A73.288 (Abstract).
7. GHO BCG, ESKILDSEN-HELMOND YEG, DE ZEEUW S, LAMERS JMJ, VERDOUW PD, 1996. Does protein kinase C play a pivotal role in the mechanisms of ischemic preconditioning? Cardiovasc Drugs Ther 10: 775-786.
8. GSCHWENDT M, DIETERICH S, RENNECKE J, KITTSETIN W, MUELLER H-J, JOHANNES F-J, 1996. Inhibition of protein kinase C m by various inhibitors. Differentiation from protein kinase C isoenzymes. FEBS Lett 392: 77-80.
9. HERGET T, BROAD S, ROZENGURT E, 1994. Overexpression of the myristoylated alanine-rich C-kinase substrate in Rat1 cells increases sensitivity to calmodulin antagonists. Eur J Biochem 225: 549-556.
10. 1B-adrenoceptors, pertussis toxin-sensitive G proteins, and protein kinase C. Circulation 92: 2259-2265.
11. LAWSON CS, DOWNEY JM, 1993. Preconditioning: state of the art myocardial protection. Cardiovasc Res 27: 542-550.
12. 1 adenosine receptors in rabbit heart. Circulation 84: 350-356.
13. LIU Y, YTREHUS K, DOWNEY JM, 1994. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium. J Mol Cell Cardiol 26: 661-668.
14. LORCA T, CRUZALEGUI FH, FESQUET D, CAVADORE J-C, MERY J, MEANS A, DOREE M, 1993. Calmodulin-dependent protein kinase II mediated inactivation of MPF and CSF upon fertilization of Xenopus eggs. Nature 366: 270-273.
15. JOHANNES F-J, PRESTLE J, EIS S, OBERHAGEMANN P, PFIZENMAIER K, 1994. PKCμ is a novel, atypical member of the protein kinase C family. J Biol Chem 269: 6140-6148.
16. JOHANNES F-J, PRESTLE J, DIETERICH S, OBERHAGEMANN P, LINK G, PFIZENMAIER K, 1995. Characterization of activators and inhibitors of protein kinase Cμ. Eur J Biochem 227: 303-307.
17. MITCHELL MB, MENG X, AO L, BROWN JM, HARKEN AH, BANERJEE A, 1995. Preconditioning of isolated rat heart is mediated by protein kinase C. Circ Res 76: 73-81.
18. 2+/calmodulin-dependent protein kinase V from rat cerebrum. J Biol Chem 268: 9143-9147.
19. 1-adrenergic signal transduction pathway or protein kinase C in the isolated rat heart. Cardiovasc Drugs Ther 10: 125-136.
20. MURRY CE, JENNINGS RB, REIMER KA, 1986. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 75: 1124-1136.
21. PRZYKLENK K, KLONER RA, 1996. Role of protein kinase C in ischemic preconditioning: in search of the "pure and simple truth". Basic Res Cardiol 91: 41-43.
22. SIMKHOVICH BZ, PRZYKLENK K, HALE SL, KLONER RA, 1995. Subcellular distribution of protein kinase C is not altered by brief preconditioning ischemia in rabbit myocardium. Circulation 92(Suppl. I): I-137 (Abstract).
23. SPEECHLY-DICK ME, MOCANU MM, YELLON DM, 1994. Protein kinase C: its role in ischemic preconditioning in the rat. Circ Res 75: 586-590.
24. VALVERDE AM, SINNETT-SMITH J, VAN LINT J, ROZENGURT E, 1994. Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain. Proc Natl Acad Sci USA 91: 8572-8576.
25. VAN LINT J, SINNETT-SMITH J, ROZENGURT E, 1995. Expression and characterization of PKD, a phorbol ester and diacylglycerol-stimulated serine protein kinase. J Biol Chem 270: 1455-1461.
26. VOGT A, HTUN P, ARRAS M, PODZUWEIT T, SCHAPER W, 1996. Intramyocardial infusion of tool drugs for the study of molecular mechanisms in ischemic preconditioning. Basic Res Cardiol 91: 389-400.
27. WALKER DM, WALKER JM, PUGSLEY WB, PATTISON CW, YELLON DM, 1995. Preconditioning in isolated super-fused human muscle. J Mol Cell Cardiol 27: 1349-1357.
28. WATSON JE, KARMAZYN M, 1991. Concentration-dependent effects of protein kinase C-activating and -nonactivating phorbol esters on myocardial contractility, coronary resistance, energy metabolism, prostacyclin synthesis, and ultrastructure in isolated rat hearts. Effects of amiloride. Circ Res 69: 1114-1131.
29. YELLON DM, ALKHULAIFI AM, PUGSLEY WB, 1993. Preconditioning the human myocardium. Lancet 342: 276-277.
30. ZUGAZA JL, SINNETT-SMITH J, VAN LINT J, ROZENGURT E, 1996. Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. EMBO J 15: 6220-6230.