Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain

Biochemistry

Volumn 40, Issue 30, 2001, Pages 8930-8939

  Elleman, T C ^a   Domagala, T ^b   McKern, N M ^a   Nerrie, M ^b   Lonnqvist B ^c   Adams, T E ^a   Lewis, J ^a,b   Lovrecz, G O ^a,b   Hoyne, P A ^a   Richards, K M ^a   Howlett, G J ^d   Rothacker, J ^b   Jorissen, R N ^b   Lou, M ^a,b   Garrett, T P J ^a,b   Burgess, A W ^b   Nice, E C ^b   Ward, C W ^a,b  

^a CSIRO   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTORS (EGFRS);

AMINO ACIDS; ANTIBODIES; CENTRIFUGATION; CHEMICAL BONDS; MUTAGENS;

BIOCHEMISTRY;

ARGININE; DIMER; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUTAMINE; GLYCINE; LIGAND; LYSINE; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR ALPHA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPETITIVE INHIBITION; HUMAN; LIGAND BINDING; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; ULTRACENTRIFUGATION;

ANIMALS; BINDING, COMPETITIVE; BIOSENSING TECHNIQUES; CELL LINE; CHICKENS; CHO CELLS; CRICETINAE; DIMERIZATION; EPIDERMAL GROWTH FACTOR; GROWTH INHIBITORS; HUMANS; LIGANDS; MICE; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SEQUENCE DELETION; TRANSFECTION; TRANSFORMING GROWTH FACTOR ALPHA;

GALLUS GALLUS; MURINAE;

EID: 0035979381     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi010037b     Document Type: Article

References (53)