Ligand-binding enhances the affinity of dimerization of the extracellular domain of the epidermal growth factor receptor

Journal of Biochemistry

Volumn 122, Issue 1, 1997, Pages 116-121

  Odaka, Masafumi ^a,c   Kohda, Daisuke ^a,d   Lax, Irit ^b   Schlessinger, Joseph ^b   Inagaki, Fuyuhiko ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d BIOMOL ENG RESEARCH INSTITUTE   (Japan)

Author keywords

Epidermal growth factor; Epidermal growth factor receptor; Laser light scattering; Ligand induced dimerization; Ligand receptor binding stoichiometry

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; DISSOCIATION CONSTANT; EXTRACELLULAR FLUID; LIGAND BINDING; LIGHT SCATTERING; PROPRIOCEPTION; PROTEIN DOMAIN; RECEPTOR BINDING; STOICHIOMETRY;

EID: 0030737618     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021718     Document Type: Article

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