Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin

Organic Letters

Volumn 3, Issue 26, 2001, Pages 4239-4242

  Sternson, Scott M ^a   Wong, Jason C ^a   Grozinger, Christina M ^a   Schreiber, Stuart L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ENZYME INHIBITOR; HISTONE DEACETYLASE; HYDROXAMIC ACID; PEPTIDE; TRAPOXIN A;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ENZYME INHIBITORS; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; PEPTIDES; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035961036     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol016915f     Document Type: Article

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