Conditional Liver-specific Expression of Simian Virus 40 T Antigen Leads to Regulatable Development of Hepatic Neoplasm in Transgenic Mice

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13989-13994

  Manickan, Elanchezhiyan ^a   Satoi, Jujin ^a   Wang, Timothy C ^b   Liang, T Jake ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; ANTIGENS; DISEASES; GENES; LIVING SYSTEMS STUDIES; PROTEINS; TISSUE; VIRUSES;

TRANSCRIPTIONAL ACTIVATORS;

BIOLOGICAL ORGANS;

BETA GALACTOSIDASE; RNA; TETRACYCLINE; VIRUS T ANTIGEN; ALBUMINOID; ANTIINFECTIVE AGENT; MAJOR URINARY PROTEINS; PROTEIN;

ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; ENZYME ACTIVITY; LIVER TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIMIAN VIRUS 40; TISSUE SPECIFICITY; TRANSGENIC MOUSE; ADENOMA; ANIMAL; BIOSYNTHESIS; CROSS BREEDING; GENE EXPRESSION REGULATION; GENE TRANSFER; GENETICS; GENOTYPE; HYPERPLASIA; LACTOSE OPERON; LIVER; METABOLISM; PATHOLOGY; PROMOTER REGION; SPLEEN; TRANSACTIVATION; TRANSGENE; VIROLOGY;

ANIMALIA; MUS MUSCULUS; SIMIAE; SIMIAN VIRUS 40;

ADENOMA; ALBUMINS; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CROSSES, GENETIC; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENOTYPE; HYPERPLASIA; LAC OPERON; LIVER; LIVER NEOPLASMS; MICE; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); PROTEINS; SPLEEN; TETRACYCLINE; TRANS-ACTIVATION (GENETICS); TRANSGENES;

EID: 0035958001     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009770200     Document Type: Article

References (33)

1. Kranias, E. G. (2000) Annu. Rev. Physiol. 62, 965-969
2. Sigmund, C. D. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 1425-1429
3. Jamieson, B. D., and Zack, J. A. (1999) AIDS 13, S5-S11
4. Gossen, M., Freundlieb, S., Bender, G., Muller, G., Hillen, W., and Bujard, H. (1995) Science 268, 1766-1769
5. Hennighausen, L., Wall, R. J., Tillmann, U., Li, M., and Furth, P. A. (1995) J. Cell. Biochem. 59, 463-472
6. Sutherland, H. G., Kearns, M., Morgan, H. D., Headley, A. P., Morris, C., Martin, D. I., and Whitelaw, E. (2000) Mamm. Genome 11, 347-355
7. Agha-Mohammadi, S., and Lotze, M. T. (2000) J. Clin. Invest, 105, 1177-1183
8. Sauer, B. (1998) Methods 14, 381-392
9. Sandgren, E. P., Quaife, C. J., Pinkert, C. A., Palmiter, R. D., and Brinster, R. L. (1989) Oncogene 4, 715-724
10. Shiota, G., Rhoads, D. B., Wang, T. C., Nakamura, T., and Schmidt, E. V. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 373-377
11. Held, W. A., Mullins, J. J., Kuhn, N. J., Gallagher, J. F., Gu, G. D., and Gross, K. W. (1989) EMBO J. 8, 183-191
12. Derman, E. (1981) Proc. Natl. Acad. Sci. U. S. A. 78, 5425-5429
13. Hogan, B., Constantini, F., and Lacy, E. (1994) Manipulating the Mouse Embryo: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
14. Efrat, S., Fusco-DeMane, D., Lemberg, H., al Emran, O., and Wang, X. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3576-3580
15. Furth, P. A., St. Onge, L., Boger, H., Gruss, P., Gossen, M., Kistner, A., Bujard, H., and Hennighausen, L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9302-9306
16. Araki, K., Hino, O., Miyazaki, J., and Yamamura, K. (1991) Carcinogenesis 12, 2059-2062
17. Bennoun, M., Rissel, M., Engelhardt, N., Guillouzo, A., Briand, P., and Weber-Benarous, A. (1993) Am. J. Pathol. 143, 1326-1336
18. Cullen, J. M., Sandgren, E. P., Brinster, R. L., and Maronpot, R. R. (1993) Vet. Pathol. 30, 111-118
19. Sepulveda, A. R., Finegold, M. J., Smith, B., Slagle, B. L., DeMayo, J. L., Shen, R. F., Woo, S. L., and Butel, J. S. (1989) Cancer Res. 49, 6108-6117
20. Hino, O., Kitagawa, T., Nomura, K., Ohtake, K., Cui, L., Furuta, Y., and Aizawa, S. (1991) Jpn. J. Cancer Res. 82, 1226-1233
21. Ewald, D., Li, M., Efrat, S., Auer, G., Wall, R. J., Furth, P. A., and Hennighausen, L. (1996) Science 273, 1384-1386
22. Gossen, M., and Bujard, H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5547-5551
23. Passman, R. S., and Fishman, G. I. (1994) J. Clin. Invest. 94, 2421-2425
24. Kistner, A., Gossen, M., Zimmermann, F., Jerecic, J., Ullmer, C., Lubbert, H., and Bujard, H. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 10933-10938
25. Sundstrom, L. (1998) APMIS Suppl. 84, 37-42
26. Wang, Y., Krushel, L. A., and Edelman, G. M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3932-3936
27. Li, L. P., Schlag, P. M., and Blankenstein, T. (1997) Hum. Gene Ther. 8, 1695-1700
28. Wakita, T., Taya, C., Katsume, A., Kato, J., Yonekawa, H., Kanegae, Y., Saito, I., Hayashi, Y., Koike, M., and Kohara, M. (1998) J. Biol. Chem. 273, 9001-9006
29. Wang, Y., DeMayo, F. J., Tsai, S. Y., and O'Malley, B. W. (1997) Nat. Biotechnol. 15, 239-243
30. No, D., Yao, T. P., and Evans, R. M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3346-3351
31. Rivera, V. M., Clackson, T., Natesan, S., Pollock, R., Amara, J. F., Keenan, T., Magari, S. R., Phillips, T., Courage, N. L., Cerasoli, F., Jr., Holt, D. A., and Gilman, M. (1996) Nat. Med. 2, 1028-1032
32. Serguera, C., Bohl, D., Rolland, E., Prevost, P., and Heard, J. M. (1999) Hum. Gene Ther. 10, 375-383
33. Kawamura, T., Furusaka, A., Koziel, M., Chung, R. T., Wang, T. C., Schmidt, E. V., and Liang, T. J. (1997) Hepatology 25, 1014-1021