Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): Implications for mechanism of action

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 3, 2000, Pages 732-738

  Adrian, Peter V ^a,c   Zhao, Wenjun ^b   Black, Todd A ^b   Shaw, Karen J ^b   Hare, Roberta S ^b   Klugman, Keith P ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b MERCK RESEARCH LABORATORIES   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EVERNIMICIN; GUANINE; ISOLEUCINE; RIBOSOME PROTEIN; SERINE; THYMINE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE MUTATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STREPTOCOCCUS PNEUMONIAE;

AMINO ACID SEQUENCE; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MICROBIAL; HUMANS; ISOLEUCINE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; PNEUMOCOCCAL INFECTIONS; RIBOSOMAL PROTEINS; SEQUENCE ANALYSIS, DNA; STREPTOCOCCUS PNEUMONIAE; TRANSFORMATION, BACTERIAL;

EID: 0033996649     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.3.732-738.2000     Document Type: Article

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