Evernimicin binds exclusively to the 50S ribosomal subunit and inhibits translation in cell-free systems derived from both gram-positive and gram- negative bacteria

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 5, 2000, Pages 1121-1126

  Mcnicholas, Paul M ^a   Najarian, David J ^a   Mann, Paul A ^a   Hesk, David ^a   Hare, Roberta S ^a   Shaw, Karen J ^a   Black, Todd A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AVILAMYCIN; EVERNIMICIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL FREE SYSTEM; GENETIC TRANSCRIPTION; GRAM NEGATIVE SEPSIS; GRAM POSITIVE BACTERIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RABBIT; REGRESSION ANALYSIS; RETICULOCYTE; RIBOSOME; STAPHYLOCOCCUS AUREUS; WHEAT GERM;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BINDING, COMPETITIVE; CARBON RADIOISOTOPES; CELL-FREE SYSTEM; ESCHERICHIA COLI; PROTEIN BIOSYNTHESIS; RABBITS; RIBOSOMES; STAPHYLOCOCCUS AUREUS;

EID: 0034052755     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.5.1121-1126.2000     Document Type: Article

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